|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | BmCH25H,a vertebrate interferon-stimulated gene(ISG)homolog,inhibits BmNPV infection dependent on its hydroxylase activity in Bombyx mori显示文摘Cholesterol-25-hydroxylase(CH25H)has been identified as an interferon-stimulated gene(ISG)in mammals that exerts its antiviral effects by catalyzing the conversion of cholesterol to 25-hydroxycholesterol(25HC).However,invertebrates lack an antiviral system homologous to vertebrate interferons(IFNs)because the genomes of invertebrates do not encode IFN-like cytokines.Nevertheless,CH25H is present in insect genomes and it therefore deserves further study of whether and by which mechanism it could exert an antiviral effect in invertebrates.In this study,the Bombyx mori CH25H(BmCH25H)gene,of which the encoded protein has high homology with other lepidopteran species,was identified and located on chromosome 9.Interestingly,we found that the expression of BmCH25H was significantly upregulated in B.mori nucleopolyhedrovirus(BmNPV)-infected BmN cells and silkworm(B.mori)larvae at the early infection stage.The inhibitory effect of BmCH25H on BmNPV replication was further demonstrated to depend on its catalytic residues to convert cholesterol to 25HC.More importantly,we demonstrated that during BmNPV infection,BmCH25H expression was increased through the Janus kinase–signal transducer and activator of transcription(JAK–STAT)pathway,similar to the induction of ISGs following virus infection in vertebrates.This is the first report that CH25H has antiviral effects in insects;the study also elucidates the regulation of its expression and its mechanism of action. | Hongyun Wu Junming Xia Shigang Fei Yeyuan Wang Mengmeng Zhang Yiyao Guo Xian Li Luc Swevers Jingchen Sun Min Feng | 2023 | Insect Science2023，30，2： | 2 |
| 2 | Accurate tracking control of linear synchronous motor machine tool axes 显示文摘 | Braembussche P V Swevers J Brussel H V | 1996 | Mechatronics1996，6，5： | 1 |
| 3 | Modeling of dry sliding friction dynamics: From heuristic model to physically motivated models and back显示文摘 | BENDER F A LAMPAERT V SWEVERS J | 2004 | Chaos2004，14，2： | 1 |
| 4 | Experimental design for Vibration Analysis on agricultural Spraying Ma- chines 显示文摘 | L Clijmans J Swevers J DeBaerdemaeker | 1998 | Proceedings of the International Conference on Noise and Vibration Engineering1998，，3： | 1 |
| 5 | The piRNA response to BmNPV infection in the silkworm fat body and midgut显示文摘Bombyx mori nucleopolyhedrovirus(BmNPV)is a DNA virus that causes huge losses to the silkworm industry but the piRNA responses during BmNPV infection in the silkworm remain uninvestigated.Here,silkworm piRNA profiles of uninfected and BmNPV-infected fat body and midgut were determined by high-through sequencing in the early stages of BmNPV infection.A total of 2675 and 3396 genome-derived piRNAs were identified from fat body and midgut,respectively.These genome-derived piRNAs mainly originated from unannotated instead of transposon regions in the silkworm genome.In total,572 piRNAs were associated with 280 putative target genes in fat body and 805 piRNAs with 380 target genes in midgut.Compared to uninfected tissues,322 and 129 piRNAs were significantly upregulated in BmNPV-infected fat body and midgut,respectively.In addition,276 and 117 piRNAs were significantly downregulated.Moreover,differentially expressed(DE)piRNAs during BmNPV infection differed significantly between fat body and midgut.Putative DE piRNA-targeted genes were associated with“response to stimulus”and“environmental information processing”in fat body after infection with BmNPV,which may indicate an active piRNA response to BmNPV infection in fat body.This study may lay the foundation for future research of the potential roles of the piRNA pathway and specific piRNAs in BmNPV pathogenesis. | Min Feng Anna Kolliopoulou Yao-Hong Zhou Shi-Gang Fei Jun-Ming Xia Luc Swevers Jing-Chen Sun | 2021 | Insect Science2021，28，3： | 1 |
| 6 | Friction Compensation of an XY Feed Table UsingFrictionModel-Based Feedforward and an Inverse-Model-Based Disturbance Observer显示文摘 | Zamberi Jamaludin Hendrik Van Brussel and Jan Swevers | 2009 | IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS2009，56，10： | 1 |
| 7 | The generalized maxwell- slip model: a novel model for friction simulation and compensation显示文摘 | F A1-Bender Lampaert V Swevers J | 2005 | IEEE Transactions On Automatic Control2005，50，11： | 1 |
| 8 | The genera- lized Maxwell-slip model: a novel model for friction simulation and compensation显示文摘 | Al-Bender F Lampaert V Swevers J | 2005 | IEEE Transactions on Automatic Control2005，50，11： | 1 |
| 9 | An integrated friction model structure with improved presliding behavior for accurate friction compens- ation显示文摘 | Swevers J Al-Bender F Ganseman C G | 2000 | IEEE Transactions on Automatic Control2000，45，4： | 1 |
| 10 | Robust linear control of an active suspension on a quarter car test-rig显示文摘 | LAUWERYS C SWEVERS J SAS P | 2005 | Control Engineering Practice2005，13，5： | 1 |
| 11 | Time-optimal path tracking for robots: A convex optimization approach显示文摘 | VERSCHEURE D DEMEULENAERE B SWEVERS J | 2009 | IEEE Transactions on Automatic Control2009，54，10： | 1 |
| 12 | An integ rated friction model structure with improved presliding behavior for accurate friction compensation显示文摘 | Al-Bender F Ganseman C G Projogo T | 2000 | IEEE Tran-Sactionson Automatic Control2000，45，4： | 1 |
| 13 | The generalized maxwell- slip model:a novel model for friction simulation and compensa- tion 显示文摘 | A1-Bender F Lampaert V Swevers J | 2005 | IEEE Transactions on Automatic Control2005，50，11： | 1 |
| 14 | Bombyx EcR(BmEcR) and Bombyx USP(BmCF1)combine to form a functional ecdysone receptor显示文摘 | Swevers L Cherbas L Cherbas P | | 0，，03： | 1 |
| 15 | Robust linear control of an active suspension on a quarter car test-rig显示文摘 | Christophe Lauwerys Jan Swevers Paul Sas | 2005 | Control Engineering Practice2005，13，5： | 1 |
| 16 | Accurate tracking control of linear synchronous motor machine tool axes显示文摘 | Braembussch P V D Swevers J Brussel H V | 1996 | Mechatronics1996，6，5： | 1 |
| 17 | Gain-scheduling contral of machine tools with varying structural flexibility 显示文摘 | SYMENS W VAN BRUSSEL H SWEVERS J | 2004 | CIRP Annals-Manufacturing Technology2004，53，： | 1 |
| 18 | An integrated friction model structure with improved presliding behavior for accurate friction compensation显示文摘 | SWEVERS J FARID A B GANSEMAN C G | 2000 | IEEE Transactions on Automatic Control2000，45，4： | 1 |
| 19 | Experimental robot identification using optimized periodic trajectories显示文摘 | Swevers J Ganseman C Schutter J D | 1996 | Mechan- ical Systems and Signal Processing1996，10，5： | 1 |
| 20 | Optimal robot dynamics excitation and identification显示文摘 | Chris G | 1997 | IEEE Trans Robot Automat1997，13，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员