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| 1 | Roux-en-Y versus BillrothⅠreconstruction after distal gastrectomy for gastric cancer:A meta-analysis显示文摘AIM:To conduct a meta-analysis to compare Rouxen-Y(R-Y) gastrojejunostomy with gastroduodenal Billroth Ⅰ(B-Ⅰ) anastomosis after distal gastrectomy(DG) for gastric cancer.METHODS:A literature search was performed to identify studies comparing R-Y with B-Ⅰ after DG for gastric cancer from January 1990 to November 2012 in Medline,Embase,Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in The Cochrane Library.Pooled odds ratios(OR) or weighted mean differences(WMD) with 95%CI were calculated using either fixed or random effects model.Operative outcomes such as operation time,intraoperative blood loss and postoperative outcomes such as anastomotic leakage and stricture,bile reflux,remnant gastritis,reflux esophagitis,dumping symptoms,delayed gastric emptying and hospital stay were the main outcomes assessed.Meta-analyses were performed using RevMan 5.0 software(Cochrane library).RESULTS:Four randomized controlled trials(RCTs) and 9 non-randomized observational clinical studies(OCS) involving 478 and 1402 patients respectively were included.Meta-analysis of RCTs revealed that R-Y reconstruction was associated with a reduced bile reflux(OR 0.04,95%CI:0.01,0.14;P < 0.00 001) and remnant gastritis(OR 0.43,95%CI:0.28,0.66;P = 0.0001),however needing a longer operation time(WMD 40.02,95%CI:13.93,66.11;P = 0.003).Metaanalysis of OCS also revealed R-Y reconstruction had a lower incidence of bile reflux(OR 0.21,95%CI:0.08,0.54;P = 0.001),remnant gastritis(OR 0.18,95%CI:0.11,0.29;P < 0.00 001) and reflux esophagitis(OR 0.48,95%CI:0.26,0.89;P = 0.02).However,this reconstruction method was found to be associated with a longer operation time(WMD 31.30,95%CI:12.99,49.60;P = 0.0008).CONCLUSION:This systematic review point towards some clinical advantages that are rendered by R-Y compared to B-Ⅰ reconstruction post DG.However there is a need for further adequately powered,welldesigned RCTs comparing the same. | Jun-Jie Xiong Kiran Altaf Muhammad A Javed Quentin M Nunes Wei Huang Gang Mai Chun-Lu Tan Rajarshi Mukherjee Robert Sutton Wei-Ming Hu Xu-Bao Liu | 2013 | World Journal of Gastroenterology2013，19，7： | 33 |
| 2 | Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma显示文摘AIM:To conduct a meta-analysis to determine the safety and efficacy of laparoscopic liver resection(LLR) and open liver resection(OLR) for hepatocellular carcinoma(HCC).METHODS:PubMed(Medline),EMBASE and Science Citation Index Expanded and Cochrane Central Register of Controlled Trials in the Cochrane Library were searched systematically to identify relevant comparative studies reporting outcomes for both LLR and OLR for HCC between January 1992 and February 2012.Two authors independently assessed the trials for inclusion and extracted the data.Meta-analysis was performed using Review Manager Version 5.0 software(The Cochrane Collaboration,Oxford,United Kingdom).Pooled odds ratios(OR) or weighted mean differences(WMD) with 95%CI were calculated using either fixed effects(Mantel-Haenszel method) or random effects models(DerSimonian and Laird method).Evaluated endpoints were operative outcomes(operation time,intraoperative blood loss,blood transfusion requirement),postoperative outcomes(liver failure,cirrhotic decompensation/ascites,bile leakage,postoperative bleeding,pulmonary complications,intraabdominal abscess,mortality,hospital stay and oncologic outcomes(positive resection margins and tumor recurrence).RESULTS:Fifteen eligible non-randomized studies were identified,out of which,9 high-quality studies involving 550 patients were included,with 234 patients in the LLR group and 316 patients in the OLR group.LLR was associated with significantly lower intraoperative blood loss,based on six studies with 333 patients [WMD:-129.48 mL;95%CI:-224.76-(-34.21) mL;P = 0.008].Seven studies involving 416 patients were included to assess blood transfusion requirement between the two groups.The LLR group had lower blood transfusion requirement(OR:0.49;95%CI:0.26-0.91;P = 0.02).While analyzing hospital stay,six studies with 333 patients were included.Patients in the LLR group were found to have shorter hospital stay [WMD:-3.19 d;95%CI:-4.09-(-2.28) d;P < 0.00001] than their OLR counterpart.Seven studies including 416 patients were pooled together to estimate the odds of developing postoperative ascites in the patient groups.The LLR group appeared to have a lower incidence of postoperative ascites(OR:0.32;95%CI:0.16-0.61;P = 0.0006) as compared with OLR patients.Similarly,fewer patients had liver failure in the LLR group than in the OLR group(OR:0.15;95%CI:0.02-0.95;P =0.04).However,no significant differences were found between the two approaches with regards to operation time [WMD:4.69 min;95%CI:-22.62-32 min;P = 0.74],bile leakage(OR:0.55;95%CI:0.10-3.12;P = 0.50),postoperative bleeding(OR:0.54;95%CI:0.20-1.45;P = 0.22),pulmonary complications(OR:0.43;95%CI:0.18-1.04;P = 0.06),intra-abdominal abscesses(OR:0.21;95%CI:0.01-4.53;P = 0.32),mortality(OR:0.46;95%CI:0.14-1.51;P = 0.20),presence of positive resection margins(OR:0.59;95%CI:0.21-1.62;P = 0.31) and tumor recurrence(OR:0.95;95%CI:0.62-1.46;P = 0.81).CONCLUSION:LLR appears to be a safe and feasible option for resection of HCC in selected patients based on current evidence.However,further appropriately designed randomized controlled trials should be undertaken to ascertain these findings. | Jun-Jie Xiong Kiran Altaf Muhammad A Javed Wei Huang Rajarshi Mukherjee Gang Mai Robert Sutton Xu-Bao Liu Wei-Ming Hu | 2012 | World Journal of Gastroenterology2012，18，45： | 25 |
| 3 | Validation of the moderate severity category of acute pancreatitis defined by determinant-based classification显示文摘BACKGROUND: Recent international multidisciplinary consultation proposed the use of local(sterile or infected pancreatic necrosis) and/or systemic determinants(organ failure) in the stratification of acute pancreatitis. The present study was to validate the moderate severity category by international multidisciplinary consultation definitions.METHODS: Ninety-two consecutive patients with severe acute pancreatitis(according to the 1992 Atlanta classification) were classified into(i) moderate acute pancreatitis group with the presence of sterile(peri-) pancreatic necrosis and/or transient organ failure; and(ii) severe/critical acute pancreatitis group with the presence of sterile or infected pancreatic necrosis and/or persistent organ failure. Demographic and clinical outcomes were compared between the two groups.RESULTS: Compared with the severe/critical group(n=59), the moderate group(n=33) had lower clinical and computerized tomographic scores(both P<0.05). They also had a lower incidence of pancreatic necrosis(45.5% vs 71.2%, P=0.015),infection(9.1% vs 37.3%, P=0.004), ICU admission(0% vs27.1%, P=0.001), and shorter hospital stay(15±5 vs 27±12days; P<0.001). A subgroup analysis showed that the moderate group also had significantly lower ICU admission rates, shorter hospital stay and lower rate of infection compared with the severe group(n=51). No patients died in the moderate group but7 patients died in the severe/critical group(4 for severe group).CONCLUSIONS: Our data suggest that the definition of moderate acute pancreatitis, as suggested by the international multidisciplinary consultation as sterile(peri-) pancreatic necrosis and/or transient organ failure, is an accurate category of acute pancreatitis. | Tao Jin Wei Huang Xiao-Nan Yang Ping Xue Muhammad A Javed Kiran Altaf Robert Sutton Qing Xia | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，3： | 13 |
| 4 | Potentialfor reduction of odorous compounds in seine manure through diet modification 显示文摘 | A L K B Kephart M W A Verstegen | 1998 | J Anim Sci (Submitted)1998，，： | 1 |
| 5 | Potential for reduction of odorous compounds in swine manure through diet modification显示文摘 | Sutton A L Kephart K B Verstegen M W A | 1999 | Journal of Animal Science1999，77，： | 1 |
| 6 | Relaxing price competition through product differentiation显示文摘 | Shaked A Sutton J | 1982 | Review of Economic Studies1982，49，1： | 1 |
| 7 | On the fracture of solids characterized by one or two parameters:theory and practice显示文摘 | Chao Y J Yang S Sutton M A | 1994 | Journal of the Mechanics of Physics and Solids1994，42，： | 1 |
| 8 | Non-invasive neuroimaging using near-infrared light 显示文摘 | STRANGMAN G BOAS D A SUTTON J P | 2002 | Biological Psychia- try2002，52，7： | 1 |
| 9 | Advances in light microscope stereo vision显示文摘 | Schreier H W Garcia D Sutton M A | 2004 | Experimetal Mechanics2004，44，3： | 1 |
| 10 | Application of digital correlation methods to rigid body mechanics显示文摘 | PETERSW H RANSON W F SUTTON M A | 1983 | Optical Engineering1983，22，6： | 1 |
| 11 | Unvoluntary unemployment as a perfect equilibrium in a Bargaining Model显示文摘 | Shaked A J Sutton | 1984 | Econometrica1984，52，： | 1 |
| 12 | A comparison of the effects of tramadol and morphine on gastric emptying in man显示文摘 | Murphy DB Sutton A Prescott LF | 1997 | Anaesthesia1997，52，12： | 1 |
| 13 | Effects of adding fiber sources to reduced-crude protein,amino acid-supplemented diets on nitrogen excretion,growth performance,and carcass traits of finishing pigs1,2显示文摘 | Shriver J A Carter S D Sutton A L | 2003 | Journal of Animal Science2003，81，： | 1 |
| 14 | Advances in light microscope stereo vision显示文摘 | Schreier H W Garcia D Sutton M A | 2004 | Experimental Mechanics2004，44，3： | 1 |
| 15 | GEM-2:A new multifrequency electro- magnetic sensor显示文摘 | Won I J Keiswetter D A Fields G RA and Sutton L C | 1996 | Journal of Environmental and Engineering Geophysics1996，1，2： | 1 |
| 16 | Atmospheric ammonia : E- mission, deposition and environmental impacts - Introduction 显示文摘 | Sutton M A Lee D S Dollard G J | 1998 | Atmospheric Environment1998，32，： | 1 |
| 17 | The benefits and development of windows with improved passenger containment显示文摘 | Now~41 R Sutton A | 2011 | Proceedings of Ihc Institution of Meehanieal Engineers Part F: Journal of Rail and Rapid Transit2011，225，3： | 1 |
| 18 | Metrology in a scanning electron microscope: Theoretical developments and experimental validation显示文摘 | Sutton M A Li N Garcia D | 2006 | Measurement Science and Technology2006，17，10： | 1 |
| 19 | Microstructural studies of friction stir welds in 2024-T3 aluminum显示文摘 | B Yang A P Reynolds R Taylor | 2002 | Material Science and Egineering2002，323，1： | 1 |
| 20 | Digital image correlation using Newton-Raphson method of partial differential correction显示文摘 | Bruck H A McNeill S R Sutton M A | 1989 | Experimental Mechanics1989，29，3： | 1 |
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