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    题名 作者 年代 出处 被引量
1甲状腺影像报告和数据系统在超声检查甲状腺结节中的应用显示文摘目的探讨甲状腺影像报告和数据系统(thyroid imaging reporting and data system,TI-RADS)在超声检查甲状腺结节中的诊断价值。方法收集292例(423个)甲状腺结节患者的超声资料,以组织病理学结果为参照标准,采用TI-RADS分级诊断标准进行回顾性评价。结果 423个甲状腺结节中,TI-RADS分级为1-5级者其恶性结节所占百分率分别为0(0/129)、6.3%(11/176)、33.3%(10/30)、86.8%(46/53)和100%(35/35)。对甲状腺良性结节超声检查TI-RADS分级的灵敏度、特异度、正确率、阳性预测值和阴性预测值分别为96.3%(309/321)、83.3%(85/102)、93.1%(394/423)、94.8%(309/326)和87.6%(85/97),阳性似然比、阴性似然比及Youden指数分别为5.77、0.04和79.6%。TI-RADS分级的良、恶性结节在形态、边界、内部回声、回声质地、内部构成和钙化灶方面所占比例的差异均有统计学意义(P〈0.001)。结论在甲状腺结节的超声检查中,应用TI-RADS分级诊断标准对临床诊断和治疗具有重要的指导价值。马步云 Parajuly Shyam Sundar 彭玉兰 时莹瑜 2011中国普外基础与临床杂志2011,18,8:50
2甲状腺乳头状癌的超声造影表现及其病理基础显示文摘目的探讨甲状腺乳头状癌的超声造影表现及其病理基础。方法对72例甲状腺结节患者进行常规超声和彩色多普勒超声检查,将TI-RADS≥3级的86个结节进行超声造影(CEUS)检查,经过手术和病理证实均为甲状腺乳头状癌;分析结节及甲状腺的CEUS表现,术后结节及甲状腺的病理进行CD34免疫组织化学染色。结果 86个结节的Adler血流分级分别为:0级26个,Ⅰ级34个,Ⅱ级23个,Ⅲ级3个。CEUS增强强度为低增强71个,等增强12个,高增强3个。结节与周围组织的平均强度、峰值强度、曲线下面积和CD34计数的差异有统计学意义(P<0.001),均明显低于周围组织。结论甲状腺乳头状癌的CEUS增强强度以低增强为主,其病理基础是与周围组织的微血管密度差异。马步云 金亚 Parajuly Shyam Sundar 赵海娜 姜勇 周洁宏 2014四川大学学报(医学版)2014,45,6:27
3Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs显示文摘Objective:To evaluate in ritro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential.Methods:A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use.The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi(Aspergillus funigaius),yeast(Candida albicans),gram-negative(Acirelobacter haumannii and Pseudornnruis aeruginosa)and gram-positive bacteria(Staphglococcus aureus).The activities were tested at three different concentrations of 1.00,0.10 and 0.01 mg/mL.The data was analysed using Gene data Screener program.Results:The measured antimicrobial activities indicated that out of the 58 plant extracts,15 extracts showed anti-fungal activity and 23 extracts exhibited anti-bacterial activity.Eight plant extracts have exhibited both anti-bacterial and anti-fungal activities.For instance,Eucommia ulmoides,Pohgonum cuspidcrtum,Poria cocas and Uncaria rhineophylla showed activity against both bacterial and fungal strains,indicating their broad spectrum of activity.Conclusions:The results revealed that the ethanol extracts of 30 plants out of the selected 58 possess significant antimicrobial activities.It is interesting to note that the findings from the current study are consistent with the traditional use.A clear correlation has also been found between the antimicrobial activity and the flavonoid content of the plant extracts which is in agreement with the literature.Hence.the results presented here can be used to guide the selection of potential plant species for the isolation and structure elucidation of novel antimicrobial compounds in order to establish the structure-activity relationship.This in turn is expected to lead the way to the discovery of novel antimicrobial agents for therapeutic use.Lin Zhang Anjaneya S.Ravipati Sundar R Koyyalamudi Sang Chul Jeong Narsimha Reddy John Bartlett Paul T.Smith Mercedes de la Cruz Maria Cndida Monteiro ngeles Melguizo Ester Jimnez Francisca Vicente 2013Asian Pacific Journal of Tropical Medicine2013,6,9:23
4Metallothionein:An overview显示文摘Metallothioneins (MTs) were discovered in 1957 by Margoshes and Vallee and identified as low-molecular weight and sulphydryl rich proteins. It is not surprising that most mammalian tissues contain age related basal levels of MTs since they are involved in metalloregulatory processes that include cell growth and multiplication. In an effort to understand the biology of this intriguing tumor, various biomarkers such as oncogenes, p53 tumor suppressor gene, waf 1 protein, proliferating cell nuclear antigen, telomerase, microsatellite markers and cytogenetic changes have been examined. One biomarker which has recently shown to be expressed in various human tumors but still less reported in carcinoma is MT. Immunohistochemical detection of MT proteins in cold acetone-fixed paraffin embedded liver sections was performed by the streptavidin-avidin-biotin immuno- peroxidase complex method.N Thirumoorthy KT Manisenthil Kumar A Shyam Sundar L Panayappan Malay Chatterjee 2007World Journal of Gastroenterology2007,13,7:21
5改良前外侧入路治疗老年复杂胫骨平台骨折的临床效果显示文摘目的探讨采用改良前外侧入路治疗老年Schatzker V型及VI型骨折的优势。方法对我院2016~2018年收治的35例老年复杂性胫骨平台骨折患者(Schatzker V型及VI型)的临床资料进行分析。均采用改良前外侧入路进行手术治疗。术后即刻及1、2、3、6、12个月对患者进行X线片检查,测量胫骨平台内翻角(tibial plateau angle,TPA)及后倾角(posterior slope angle,PA),采用Rasmussen放射学评分评价手术复位及骨折愈合情况,采用Rasmussen膝关节功能评分及美国纽约特种外科医院(HSS)评分系统,对患者膝关节功能康复进行评价。结果本组共35例,其中男15例,女20例,年龄61~81岁,平均(69.46±6.15)岁。Schatzker分型V型20例,VI型15例。术后即刻X线片显示共30例获解剖复位,5例关节面遗留<2 mm台阶。Rasmussen放射学评分12~18分,平均(16.26±1.93)分。各时间点TPA值相比,差异无统计学意义(F=0.05,P=0.99)。各时间点内侧PA值相比,差异无统计学意义(F=0.08,P=0.99)。各时间点外侧PA值相比,差异无统计学意义(F=0.07,P=0.98)。术后HSS评分为79~95分,平均(86.51±4.29)分。Rasmussen膝关节功能评分为18~29分,平均(25.54±2.96)分。膝关节活动范围为90°~135°,平均(120.37±10.99)°。所有患者术后1年随访均显示骨折愈合。结论采用改良前外侧入路治疗老年Schatzker V型及VI型胫骨平台骨折具有术中软组织损伤小的特点,且Rasmussen评分及HSS评分显示术后膝关节功能恢复满意。刘燊 Shyam Sundar Thakur 程鑫 郝岩 张晓雷 郝丁宇 张磊 周先虎 冯世庆 2019中国骨与关节杂志2019,8,7:19
6结节性筋膜炎的组织病理学分型及其超声表现显示文摘目的分析结节性筋膜炎的组织病理学分型及其相应二维及彩色多普勒超声声像图特征,探讨超声诊断结节性筋膜炎的价值。方法分析27例经手术病理证实的结节性筋膜炎患者的二维和彩色多普勒超声声像图特征及与其组织病理学分型的相关性。结果结节性筋膜炎超声声像图表现多样,共有特征为皮下或肌层内弱回声团块,病变多数小于3 cm。不同组织病理学分型的超声表现具有一定特征。按照病变部位可分为皮下型、筋膜型及肌内型,其中皮下型多与深筋膜关系密切;筋膜型具有特征性的沿浅筋膜和皮下脂肪小叶的纤维间隔伸展,呈'星状'突起的超声表现。根据病变结构不同可分为黏液型、细胞型和纤维型,黏液型团块内部可有小片状无回声区,边缘有血流;细胞型团块内部及边缘有血流,且边缘血流明显,而纤维型无明显血流。结论不同分型结节性筋膜炎具有一定特征;二维及彩色多普勒超声可作为结节性筋膜炎诊断的重要辅助检查。张静漪 邱逦 Shyam Sundar Parajuly 2011中国医学影像技术2011,27,4:15
7滑膜肉瘤的二维及彩色多普勒超声特征显示文摘目的探讨滑膜肉瘤的二维及彩色多普勒声像图特征。方法回顾性分析26例经手术病理证实的滑膜肉瘤患者的超声声像图特征。结果 26例滑膜肉瘤中,17例发生于中青年,二维超声显示均未累及关节腔,表现为弱回声团块,其中20例内部回声不均匀,19例伴液化,7例伴钙化;血流分级:0级5例,Ⅰ级1例,Ⅱ级7例,Ⅲ级13例。15例位于关节旁,与11例非关节旁病灶在深度、最大径、边界、形态、血流信号等方面的差异均无统计学意义(P均>0.05)。20例病变体积较大,与6例体积较小者在病变位置、形态、内部回声及血流信号方面的差异均有统计学意义(P均<0.05)。结论滑膜肉瘤的超声表现具有一定特征性,有助于提高诊断准确率。唐远姣 冷钱英 Parajuly Shyam Sundar 邱逦 2014中国医学影像技术2014,30,2:10
8一种新型的T形一维镉配位聚合物[Cd(C_5H_4NCOO)·(C_5H_5NCOO)·(NO_3)·(H_2O)]_n(英文)显示文摘Cd(NO3)2· 6H2O和 4-(4-羧基吡啶 )氨基苯甲醛通过温和条件下的水热反应制备了一种新型的中性 T形一维链状配位聚合物,聚合 [(异烟酸根)( 4-羧酸根基吡啶铵)水合硝酸镉 ]。该配合物显示了蓝色荧光性质。曾锡瑞 熊仁根 游效曾 S.Shanmuga Sundar Raj Hoong-Kun Func 2000无机化学学报2000,16,4:10
9超声引导下乳腺肿瘤穿刺活检术的护理配合流程显示文摘近年来,乳腺疾病的发病率呈上升趋势,乳腺癌的高发病率及年轻化,严重威胁女性的身体和心理健康。由于乳腺肿瘤病理性质的判定,对选择不同的治疗方案和外科术式具有重要的临床意义比。目前,对乳腺肿瘤多采用高频超声引导下粗针穿刺活检术(ultrasound—guidedpuncturebiopsy,UPB),梁丽 彭玉兰 Parajuly Shyam Sundar 李伟 2013护士进修杂志2013,28,5:9
10Diagnostic value of contrast enhanced ultrasound for splenic artery complications following acute pancreatitis显示文摘AIM:To assess the value of contrast-enhanced ultrasound(CEUS)in diagnosing splenic artery complications(SACs)after acute pancreatitis(AP).METHODS:One hundred and eighteen patients with AP were enrolled in the study.All patients were examined by CEUS and contrast-enhanced computed tomography(CECT).CECT was accepted as a gold standard for the diagnosis of SACs in AP.The diagnostic accuracy of splenic CEUS and pancreatic CEUS was compared with that of CECT.Splenic infarction was the diagnostic criterion for splenic artery embolism and local dysperfusion of the splenic parenchyma was the diagnostic criterion for splenic arterial stenosis.The incidence of splenic sub-capsular hemorrhage,splenic artery aneurysms,and splenic rupture was all lower than that of SACs.RESULTS:Nine patients were diagnosed as having SACs after AP by CECT among the 118 patients.The patients with SACs were diagnosed with severe acute pancreatitis(SAP).Among them,6 lesions were diagnosed as splenic artery embolism,5 as splenic artery aneurysms,and 1 as splenic arterial stenosis.No lesion was diagnosed by pancreatic CEUS and 5 lesions were diagnosed by splenic CEUS.By splenic CEUS,4 cases were diagnosed as splenic artery embolism and 1 as splenic arterial stenosis.The accuracy of splenic CEUS in diagnosis of SACs in SAP was 41.7%(5/12),which was higher than that of pancreatic CEUS(0%).CONCLUSION:Splenic CEUS is a supplementary method for pancreatic CEUS in AP patients,which can decrease missed diagnosis of SACs.Di-Ming Cai Shyam Sundar Parajuly Wen-Wu Ling Yong-Zhong Li Yan Luo 2014World Journal of Gastroenterology2014,20,4:8
11东莨菪亭(7-羟基-6-甲氧基香豆素)对7 ,12-二甲基苯并蒽诱导的皮肤乳头状瘤小鼠相关关键信号蛋白的影响(英文)显示文摘目的:东莨菪亭(7-羟基-6-甲氧基香豆素)是从常绿钩吻中提取的有效成分,前期体外研究证实了其抗肿瘤潜能,本研究评价其在小鼠体内的抗肿瘤作用。方法:30只健康小鼠随机分为正常对照组、模型组、溶剂对照组和低、高剂量东莨菪亭组,每组6只。正常对照组小鼠不接受任何干预,其余小鼠背部涂抹100μg 7 ,12-二甲基苯并蒽(7 ,12-di methylbenz[a]anthra-cene ,DMBA)(每周一次)和1 %巴豆油(每周2次)诱导皮肤乳头状瘤,共24周。溶剂组小鼠在造模基础上每天予2 %酒精口服,低剂量(50 mg/kg)和高剂量(100 mg/kg)东莨菪亭组小鼠每天予东莨菪亭治疗。治疗24周后,检测碱性磷酸酶、超氧化物歧化酶、过氧化氢酶、谷胱甘肽过氧化物酶和谷胱甘肽S-转移酶活性;信号蛋白及其受体,包括芳香烃受体(Aryl hydrocarbon receptor , AhR)、p53、细胞色素P450亚酶1A1(cytochrome P450 1A1 , CYP1A1)、增殖细胞核抗原(proliferating cell nuclear antigen,PCNA)、信号转导和转录激活因子3(signal transducer and activator of transcription-3 ,Stat-3)、存活素、金属基质蛋白酶2、cyclin D1、c-myc、金属蛋白酶组织抑制因子2和半胱氨酸蛋白酶3(caspase-3) ,采用逆转录聚合酶链反应、蛋白印迹法或免疫沉淀法检测。结果:致癌物DMBA和巴豆油可以诱导毒性反应,生化指标中相关酶活性升高,AhR、CYP1A1、PCNA、Stat-3、存活素、MMP-2、cyclin D1和c-myc表达上调,p53、caspase-3和TI MP-2表达下调。荷瘤小鼠采用东莨菪亭治疗后,生化指标中相关酶的活性下降,蛋白表达和毒性生物标志物恢复正常。结论:东莨菪亭可能通过下调AhR表达来下调一些重要信号蛋白的表达,其作用机制可能是通过竞争性抑制存活素的表达。分裂原活化蛋白激酶可能也起到关键作用。东莨菪亭或许可作为化疗的替代药物用于治疗肿瘤。Soumya Sundar Bhattacharyya Saili Paul Suman Dutta Naoual Boujedaini Anisur Rahman Khuda-Bukhsh 2010中西医结合学报2010,8,7:7
12Role of surgery and transplantation in the treatment of hepatic metastases from neuroendocrine tumor显示文摘Neuroendocrine tumors(NET) are a heterogeneous group of cancers, with indolent behavior. The most common primary origin is the gastro-intestinal tract but can also appear in the lungs, kidneys, adrenals, ovaries and other organs. In general, NET is usually discovered in the metastatic phase(40%-80%). The liver is the most common organ involved when metastases occur(40%-93%), followed by bone(12%-20%) and lung(8%-10%).A number of different therapeutic options are available for the treatment of hepatic metastases including surgical resection, transplantation, ablation, trans-arterial chemoembolization, chemotherapy and somatostatin analogues. Recently, molecular targeted therapies have been used, usually in combination with other treatment options, to improve outcomes in patients with metastases. This article emphasizes on the role of surgery in the treatment of liver metastases from NET.Sayee Sundar Alagusundaramoorthy Roberto Gedaly 2014World Journal of Gastroenterology2014,20,39:7
13天然植物化学成分东莨菪亭聚合物纳米胶囊的制备及其对人黑色素瘤A375细胞的作用(英文)显示文摘目的:东莨菪亭(7-羟基-6甲氧基香豆素,化学式C10H8O4,简称HMC)是从常绿钩吻(Gelsemium sem pervirens)中提取的一种天然香豆素类化合物,被认为具有抗癌活性。本研究将HMC制成聚乳酸聚乙醇酸共聚物(polylactic-co-glycolic acid,PLGA)纳米颗粒胶囊,通过多项指标观察其与非纳米HMC相比,在被细胞摄取、生物利用度及对细胞凋亡的影响(抗癌活性)等方面是否有所提高。方法:人黑色素瘤A375细胞用来检测HMC及纳米HMC颗粒(nano-7-hydroxy-6-methoxy coumarin,NHMC)的被细胞摄取率及抗癌活性;通过动态光散射确定NHMC的颗粒大小、多分散性指数及电动电位;扫描电子显微镜及原子力显微镜检测纳米颗粒的表面形态。结果:HMC制成纳米颗粒胶囊的包封率超过85%。NHMC颗粒的平均直径小于110nm,其多分散性系数为0.237,提高了其被细胞摄取率及生物活性。NHMC被细胞摄取的时间(15min)明显少于非纳米HMC(30min)。测定细胞内某些信号分子mRNA的表达,表明NHMC作用细胞后能够下调细胞周期素D1(cyclin-D1)、增殖细胞核抗原(PCNA)、存活素(survivin)及信号转导和转录活化因子3(Stat-3)的表达并上调p53及半胱天冬酶3(caspase-3)的表达。与非纳米HMC相比,NHMC能够更快地被细胞摄取并引起更多的肿瘤细胞凋亡。NHMC对正常皮肤细胞无明显细胞毒性。结论:使用生物可降解材料PLGA制成的小分子纳米颗粒NHMC能够更快速地被细胞摄取并引起更多的肿瘤细胞凋亡,而对正常皮肤细胞无明显细胞毒性。提取天然药用植物中的有效成分制成纳米颗粒胶囊有望成为更好地发挥其药效的途径。Anisur Rahman Khuda-Bukhsh Soumya Sundar Bhattacharyya Saili Paul Naoual Boujedaini 2010中西医结合学报2010,8,9:6
14乳腺脓肿行超声引导抽脓灌洗术的围手术期护理显示文摘乳腺脓肿是乳腺外科常见疾病,病人多是产后哺乳的妇女,以初产妇更为多见,常由于急性乳腺炎处理不当或不及时所致[1]。乳腺脓肿一经确诊,必须采取手术引流。传统的外科切开引流创伤大,换药时疼痛剧烈,治疗时间长,愈合后瘢痕明显,严重者可导致乳房变形,故难以被患者接受[2]。近年来,随着高频超声设备的不断发展,超声引导穿刺抽脓灌洗术因其经济、微创、有效率高及术后几乎无疤痕、美观性高等优点,逐渐在临床上得到广泛应用[3]。2009年1月~2013年1月,我院应用该技术治疗乳腺脓肿30例,效果满意。现将围手术期护理报告如下。梁丽 马步云 Parajuly Shyam Sundar 陈启锐 于波洋 2014护士进修杂志2014,29,5:6
15美洲远志根提取物对苯并芘致肺癌小鼠的抗肿瘤作用(英文)显示文摘目的:研究美洲远志(Polygala senega)根的乙醇提取物对苯并芘致肺癌小鼠的抗肿瘤作用。方法:瑞士白化小鼠被分为5组,每组6只。组1为对照组,予口服橄榄油;组2予苯并芘(50mg/kg体质量,溶于橄榄油中),每周2次,连续4周;组3除予与组2相同的苯并芘外,再予48%乙醇;组4予与组2相同的苯并芘,并同时给予美洲远志的乙醇提取物,每日1次,连续16周;组5仅给予美洲远志的乙醇提取物,每日1次,连续16周。16周后,处死所有小鼠并检测和评价以下指标:2,2-二苯基-1-苦基肼(2,2-diphenyl-1-picrylhydrazyl,DPPH)法测定美洲远志乙醇提取物的抗氧化功效;分别称取各组小鼠的肺组织质量及体质量;彗星实验及酶联免疫吸附法检测DNA损伤情况;分别测定过氧化氢酶、超氧化物歧化酶、谷胱甘肽过氧化物酶、谷胱甘肽还原酶、脂质过氧化反应及总含硫化合物含量。结果:给予美洲远志乙醇提取物治疗的组4小鼠与组3模型组小鼠相比,体质量明显增加而肺组织质量明显降低(P<0.01)。彗星实验结果显示组4小鼠的DNA损伤较组3小鼠明显减轻(P<0.01)。酶联免疫吸附法测定p53蛋白水平,组4明显高于组3(P<0.01)。组2和组3的模型小鼠与组1比较,脂质过氧化反应水平明显升高,而抗氧化标志物的水平明显降低(P<0.05),组4小鼠的这些指标被明显逆转(P<0.01)。结论:美洲远志对于化学制剂致小鼠肺癌有明确的治疗效果。Saili Paul Soumya Sundar Bhattacharyya Asmita Samaddar Naoual Boujedaini Anisur Rahman Khuda-Bukhsh 2011中西医结合学报2011,9,3:4
16打通迈向5G之路显示文摘本文介绍了通往5G的标准演进及5G带来的益处。Kalyan Sundar 2018电子产品世界2018,25,1:4
17A phylogenetic census of global diversity of gut anaerobic fungiand a new taxonomic framework显示文摘Obligate anaerobic fungi of the phylum Neocallimastigomycota play a key role in digesting fibrous feeds in the gut ofherbivores, but little is known about their global diversity. In this study, the collective diversity of gut anaerobic fungi wasexamined using all curated internal transcribed spacer 1 (ITS1) sequences of anaerobic gut fungi available in GenBank.The 262,770 quality-checked fungal ITS1 sequences downloaded from GenBank were assigned to 274 operational taxonomic units (OTUs) at the approximate species level. Of these approximate species-equivalent (Sp-eq) OTUs, 119 wererepresented by at least five ITS1 sequences, with 38 containing known species and 81 containing no known species. Basedon a rarefaction analysis, the currently available ITS1 sequences represent nearly all the major species of gut anaerobicfungi, but much more sequencing effort is needed to assess the actual richness of minor OTUs. One dataset of ITS1reference sequences (referred to as AF-RefSeq) and one comprehensive taxonomic framework are also presented, and theyare shown to be suitable for taxonomic classification of most of the ITS1 sequences in GenBank. The results of the presentstudy may help guide future studies involving taxonomic and phylogenetic analysis of ITS1 sequences of anaerobic fungiand targeted isolation and characterization of new anaerobic fungi.Shyam Sundar Paul Dengpan Bu Jianchu Xu Kevin D.Hyde Zhongtang Yu 2018Fungal Diversity2018,,2:4
18A Galeazzi-variant type fracture-dislocation in adults显示文摘有在近似或远侧的桡尺骨的关节(DRUJ ) 的脱臼任何一个的半径或尺骨的 ObjectiveFracture 不是普通损害并且内在地是不稳定的。这里,我们报导一个案例系列,与与 DRUJ 的脱臼联系的两个骨头前臂破裂,作为 Galeazzi 变体的类型破裂脱臼,并且试着分析学习基于 6 个病人有的这损害 pattern.MethodsThe 不同年龄(20 ~ 45 年) 的 Galeazzi 变体的类型破裂脱臼。所有破裂是关上的类型。二破裂包含了一样的水平,三破裂在半径和尺骨柄的不同层次。在彻底的检查和调查以后,他们与有限接触被对待没有为 DRUJ.ResultsAll 案例的另外的固定的动态压缩板被跟随在上面为 24 个星期。最大的发生发生在在 31 和 40 年之间的年龄组。半径和尺骨的所有破裂在 12 个星期的平均时间被统一。在最后的后续的手腕和肘,旋后和内转的运动的范围是正常的。没有在任何在成年人的 cases.ConclusionGaleazzi 变体的 DRUJ 的随后的 re-subluxation 或脱臼是有手腕损害的前臂的一个新 undescribed 模式。稳定的开的减小和两个骨头前臂破裂的内部固定是强制的,为破坏 DRUJ 愈合在一个演员组到 3 ~ 4 星期固定列在后面。Raju Vaishya Sundar Kumar Shrestha Abhishek Vaish 2013Chinese Journal of Traumatology2013,16,6:4
19Self-Assembled Al Nanostructure/ZnO Quantum Dot Heterostructures for High Responsivity and Fast UV Photodetector显示文摘Light confinement induced by spontaneous near-surface resonance is inherently determined by the location and geometry of metallic nanostructures(NSs),offering a facile and effective approach to break through the limitation of the light-mater interaction within the photoactive layers.Here,we demonstrate high-performance Al NS/ZnO quantum dots(Al/ZnO) heterostructure UV photodetectors with controllable morphologies of the self-assembled Al NSs.The Al/ZnO heterostructures exhibit a superior light utilization than the ZnO/Al heterostructures,and a strong morphological dependence of the Al NSs on the optical properties of the heterostructures.The inter-diffusion of Al atoms into ZnO matrixes is of a great benefit for the carrier transportation.Consequently,the optimal photocurrent of the Al/ZnO heterostructure photodetectors is significantly increased by 275 times to ~1.065 mA compared to that of the pristine ZnO device,and an outstanding photoresponsivity of 11.98 A W-1 is correspondingly achieved under 6.9 MW cm-2 UV light illumination at 10 V bias.In addition,a relatively fast response is similarly witnessed with the Al/ZnO devices,paving a path to fabricate the high-performance UV photodetectors for applications.Sisi Liu Ming‑Yu Li Jianbing Zhang Dong Su Zhen Huang Sundar Kunwar Jihoon Lee 2020Nano-Micro Letters2020,12,9:3
20Attention deficit hyperactivity disorder and comorbidity: A review of literature显示文摘Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with onset in early childhood.It is a clinically heterogenous condition with comorbidity posing a distinct challenge to diagnosing and managing these children and adolescents.This review aims to provide an overview of comorbidity with ADHD including other neurodevelopmental disorders,learning disorders,externalising and internalising disorders.Challenges in screening for,diagnosing and managing comorbidity with ADHD are summarised.Also,methodological challenges and future directions in research in this interesting field are highlighted.Sundar Gnanavel Pawan Sharma Pulkit Kaushal Sharafat Hussain 2019World Journal of Clinical Cases2019,7,17:3
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