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5篇 您的检索式:作者名="Sun Luning"
    题名 作者 年代 出处 被引量
1Physics-constrained bayesian neural network for fluid flow reconstruction with sparse and noisy data显示文摘In many applications,flow measurements are usually sparse and possibly noisy.The reconstruction of a high-resolution flow field from limited and imperfect flow information is significant yet challenging.In this work,we propose an innovative physics-constrained Bayesian deep learning approach to reconstruct flow fields from sparse,noisy velocity data,where equationbased constraints are imposed through the likelihood function and uncertainty of the reconstructed flow can be estimated.Specifically,a Bayesian deep neural network is trained on sparse measurement data to capture the flow field.In the meantime,the violation of physical laws will be penalized on a large number of spatiotemporal points where measurements are not available.A non-parametric variational inference approach is applied to enable efficient physicsconstrained Bayesian learning.Several test cases on idealized vascular flows with synthetic measurement data are studied to demonstrate the merit of the proposed method.Luning Sun Jian-Xun Wang 2020Theoretical & Applied Mechanics Letters2020,10,3:5
2Construction of the Chinese Veteran Clinical Research (CVCR) Platform for the assessment of non-communicable diseases显示文摘Tan Jiping Li Nan Gao Jing Guo Yuhe Hu Wei Yang Jinsheng Yu Baocheng Yu Jianmin Du Wei Zhang Wenjun Cui Lianqi Wang Qingsong Xia Xiangnan Li Jianjun Zhou Peiyi Zhang Baohe Liu Zhiying Zhang Shaogang Sun Lanying Liu Nan Deng Ruixiang Dai Wenguang Yi Fang Chen Wenjun Zhang Yongqing Xue Shenwu Cui Bo Zhao Yiming Wang Luning 2014Chinese Medical Journal2014,,3:3
3Combination of two multiplex genome-edited soybean varieties enables customization of protein functional properties显示文摘Dear Editor,Soybean(Glycine max)is a major source of plant-based protein for people worldwide,providing a healthy,affordable,and environmentally friendly alternative to animal-based protein(Montgomery,2003).It has been estimated that there are currently over 12000 food products that contain soy protein(Montgomery,2003).Different food applications of soy protein require distinct properties that affect its function and sensory features.For instance,the sensory quality of soymilk is significantly affected by protein emulsibility,whereas tofu quality is determined by protein-gelling ability(Kinsella,1979).Mengyan Bai Cuicui Yuan Huaqin Kuang Qian Sun Xinchen Hu Luning Cui Wenxin Lin Chunyan Peng Peng Yue Shikui Song Zebin Guo Yuefeng Guan 2022Molecular Plant2022,15,7:1
4A new weapon for gene therapy-RNA interference technology application' s summary 显示文摘Song Xiaoyu Sun Luning Zhang Haipeng 2004Journal of International Pathology and Clinical Medicine2004,24,4:1
5Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study显示文摘A simple and rapid liquid chromatography–tandem mass spectrometry(LC–MS/MS) method was developed and validated for simultaneous determination of acetaminophen and oxycodone in human plasma. Acetaminophen-d4 and oxycodone-d3 were used as internal standards. The challenge encountered in the method development that the high plasma concentration level of acetaminophen made the MS response saturated while the desired lower limit of quantification(LLOQ) for oxycodone was hard to reach was well solved. The analytes were extracted by protein precipitation using acetonitrile. The matrix effect of the analytes was avoided by chromatographic separation using a hydrophilic C18 column coupled with gradient elution. Multiple reaction monitoring in positive ion mode was performed on tandem mass spectrometer employing electrospray ion source. The calibration curves were linear over the concentration ranges of 40.0–8000 ng/m L and 0.200–40.0 ng/m L for acetaminophen and oxycodone,respectively. This method, which could contribute to high throughput analysis and better clinical drug monitoring, was successfully applied to a pharmacokinetic study in healthy Chinese volunteers.Wei Lu Shunbo Zhao Meng Gong Luning Sun Li Ding 2018Journal of Pharmaceutical Analysis2018,8,3:0
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