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87篇 您的检索式:作者名="Sumner K"
    题名 作者 年代 出处 被引量
1PI_3激酶参与AT_1受体介导Ang II调节SHR脑神经元电活动的信号转导显示文摘目的 探索AT1受体介导AngII调节SHR和WKY鼠脑神经元电活动的信号转导机制。 方法 原代培养SHR和WKY新生鼠脑干和下丘脑神经元 ,用全细胞膜片钳以电流箝方式记录神经元的放电活动 ,观察AngII及各种信号分子抑制剂对脑神经元放电频率的影响。结果 AngⅡ (10 0nmol·L-1)可使WKY新生鼠脑神经元的放电频率从 (0 .4 4± 0 .0 8)Hz增加到 (1.39± 0 .16 )Hz。这种效应在SHR鼠更加显著。由AngⅡ引起的这两种鼠脑神经元放电频率的增加均可被AT1受体拮抗剂Losartan完全消除。使用PKC抑制剂calphostinC和钙调蛋白激酶II抑制剂KN 93能完全阻断AngⅡ对WKY鼠脑神经元的作用 ,但对SHR鼠脑神经元的放电频率仅阻抑约 5 0 %。磷脂酰肌醇 3(PI3 )激酶抑制剂LY2 94 0 0 2 (10 μmol·L-1)对SHR鼠脑神经元的放电频率可产生部分阻断作用 ,但对WKY鼠脑神经元无明显影响。结论 AngII增加SHR和WKY鼠脑神经元放电频率的作用均由AT1受体介导。PI3杜剑青 孙成文 唐敬师 Colin Sumners Mohan K Raizada 2003西安交通大学学报(医学版)2003,24,6:2
2Cu+- and Cu2x-sensitive PEBBLE fluorescent nanosensors u- sing DsRed as the recognition element 显示文摘Sumner J P Westerberg N M Stoddard A K 2006Sens Actuators B2006,113,:1
3Serotonin trans- porter (SERF) mRNA and binding site densities in male rat brain affected by sex steroids 显示文摘McQueen J K Wilson H Sumner B E 1999Brain Res Mol Brain Res1999,63,2:1
4Strengthening Steel Structures and Bridges with High Modulus Carbon Fiber Reinforced Polymer:Resin Selections and Scaled Monopole Behavior显示文摘Schnerch D Stanford K Sumner E 2004Transportation Research Record2004,1892,:1
5Inverse kinematics for re- duced deformable models显示文摘Der K G Sumner R W Popovi6 J 2006ACM Transactions on Graphics2006,25,3:1
6Effect of temperature and screw speed on fumonisin B1 in extrusion-cooked corn grits 显示文摘Katta K S Jackson L S Sumner S S 1999Cereal Chemistry1999,76,1:1
7Effect of temperature and screw speed on fumonisin B1 in extrusioncooked corn grits显示文摘Katta K S Jackson L S Sumner S S 1999Cereal Chemistry1999,76,1:1
8Osteogenic differentiation of rat bone marrow stromal cells by various intensities of low-intensity pulsed ultrasound显示文摘Angle S R Sena K Sumner D R 2011Ultrasonics2011,51,3:1
9Comparison of time, frequency, and phase measurements in induced polarization 显示文摘Zonge K Sauck W Sumner J 2006Geophysical Prospecting2006,20,3:1
10The use of predictive microbiology by the Australian meat industry 显示文摘Sumner J Krist K 2002International Journal of Food Microbiology2002,73,23:1
11Integration, of partial differential equation for transient radial flow of gascondensate fluids in porous structures显示文摘Eilerts C K Sumner E F 1965SPEJ1965,1965,:1
12A WD40 repeat protein from Medicago truncatula is necessary for tissue-specific anthocyanin and proanthocyanidin biosynthesis but not for trichome development 显示文摘Pang Y Wenger J P Saathoff K Peel G J Wen J Huhman D Allen S N Tang Y Cheng X Tadege M Ratct P Mysore K S Sumner L W Marks M D Dixon R A 2009Plant Physiology2009,151,3:1
13Sex stetoid control of mood, mental state and memory显示文摘Fink G Sumner B E McQeen J K 1998Clin Exp Pharrnacol1998,25,10:1
14Impedance-based earth fault location for a non-directly grounded distribution systems显示文摘Jia K Thomas D Sumner M 2012IET Generation transmission & distribu- tion2012,6,12:1
15The use of predictive microbiology by the Australian meat industry显示文摘Sumner J Krist K 2002Food Microblol2002,73,:1
16The use of predictive microbiology by the Australian meat industry显示文摘SUMNER J KRIST K 2002International Journal of Food Microbiology2002,73,23:1
17Amelioration of acid soilinfertility lay phosphogypsum 显示文摘ALVA A K SUMNER M E 1990Plant and Soil1990,128,:1
18Convection- al magnetic shielding 显示文摘Sumner T J Pendlebury J M Smith K F 1987Journal of Physics D: Ap- plied Physics1987,20,9:1
19Cu^+- and Cu^2+- sensitive PEBBLE fluorescent nanosensors using DsRed as the recognition element显示文摘SUMNER J P WESTERBERG N M STODDARD A K 2006Sens Actuators: B2006,113,2:1
20Modulation of VEGF expression in rat bone marrow stromal cells by GDF-5显示文摘SENA K SUMNER D R VIRDI A S 2007Connective Tissue Research2007,48,6:1
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