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| 1 | Up-regulation of hypoxia-inducible factor-1α enhanced the cardioprotective effects of ischemic postconditioning in hyperlipidemic rats显示文摘Hyperlipidemia 是在 ischemic 心疾病的发展的一个独立风险因素,它能增加心肌的危险性到 ischemia/reperfusion (I/R ) 损害。Ischemic postconditioning (PostC ) 现在作为新奇策略被表明了处于正常条件对心肌的 I/R 损害利用自然的保护。然而, hyperlipidemic 动物上的 PostC 的效果留下逃犯。PostC 减少心肌的 I/R 损害,这在我们的以前的学习被显示出,并且组织缺氧可诱导的 factor-1 (HIF-1 ) 可以在正常老鼠上在 PostC 的 cardioprotective 机制起一个重要作用。这里,我们测试了 hyperlipidemic 老鼠上的 PostC 的 cardioprotection 与起来调整的 HIF-1 表示被联系的假设。男 Wistar 老鼠用一本高脂肪的食谱被喂 8 个星期,然后随机把组划分了成五:假冒, I/R, dimethyloxalylglycine (DMOG )+ I/R, PostC,和 DMOG + PostC 组织。I/R 损害导致的有害索引包括了梗塞尺寸,血浆肌酸 kinase (CK ) 活动和 caspase-3 活动。,结果与 I/R 组相比证明 PostC 能减少梗塞尺寸,它与血浆 CK 的重要底层一致活动和 caspase-3 活动,和那它在 hyperlipidemic 老鼠增加了 HIF-1 的表示。当 DMOG 在 PostC 前被给起来调整 HIF-1 蛋白质水平时, I/R 损害的度被稀释。在结论,这些数据建议 HIF-1 的起来规定可以是对在 hyperlipidemic 老鼠的 I/R 损害的 PostC 的 cardioprotective 机制之一。 | Xiaoyu Li Huanxin Zhao Ye Wu Suli Zhang Xiaoqin Zhao Yan Zhang Jin Wang Jie Wang Huirong Liu | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 9 |
| 2 | Gold-iridium bifunctional electrocatalyst for oxygen reduction and oxygen evolution reactions显示文摘Carbon supported gold-iridium composite(Au Ir/C) was synthesized by a facile one-step process and was investigated as the bifunctional catalyst for oxygen reduction reaction(ORR) and oxygen evolution reaction(OER). The physical properties of the Au Ir/C composite were characterized by transmission electron microscopy(TEM), X-ray diffraction(XRD) and X-ray photoelectron spectroscopy(XPS). Although the Au and Ir in the Au Ir/C did not form alloy, it is clear that the introduction of Ir decreases the average Au particle size to 4.2 nm compared to that in the Au/C(10.1 nm). By systematical analysis on chemical state of metal surface via XPS and the electrochemical results, it was found that the Au surface for the Au/C can be activated by potential cycling from 0.12 V to 1.72 V, resulting in the increased surface roughness of Au,thus improving the ORR activity. By the same potential cycling, the Ir surface of the Ir/C was irreversibly oxidized, leading to degraded ORR activity but uninfluenced OER activity. For the Au Ir/C, Ir protects Au against being oxidized due to the lower electronegativity of Ir. Combining the advantages of Au and Ir in catalyzing ORR and OER, the Au Ir/C catalyst displays an enhanced catalytic activity to the ORR and a comparable OER activity. In the 50-cycle accelerated aging test for the ORR and OER, the Au Ir/C displayed a satisfied stability, suggesting that the Au Ir/C catalyst is a potential bifunctional catalyst for the oxygen electrode. | Lizhi Yuan Zhao Yan Luhua Jiang Erdong Wang Suli Wang Gongquan Sun | 2016 | Journal of Energy Chemistry2016，25，5： | 2 |
| 3 | Macrophage polarization is involved in liver fibrosis induced byβ_(1)-adrenoceptor autoantibody显示文摘Accumulating evidence suggests that liver injury can be induced by the over-expression ofβ_(1)-adrenergic receptors(β_(1)-ARs).High titers of autoantibodies specific toβ_(1)-adrenergic receptors(β_(1)-AA)are detected in the sera of heart failure patients,potentially playing agonist-like roles.However,the role ofβ_(1)-AA in liver function has not been characterized.In this study,we collect the sera of primary biliary cholangitis(PBC)patients,a condition which easily develops into liver fibrosis,and analyze the relationship between PBC andβ_(1)-AA.A passive immunization model is established to assess the effect ofβ_(1)-AA on the liver.Subsequently,the effect ofβ_(1)-AA on macrophages is investigated in vitro.Results show that PBC patients have a high titer and ratio ofβ_(1)-AA,compared to controls.Liver injury and fibrosis are induced byβ_(1)-AA.In vitro experiments with ROS probe demonstrate thatβ_(1)-AA induces macrophages to produce ROS and secrete TNFα.These effects can be partially reversed by metoprolol,a blocker forβ_(1)-AR.Results from the transwell and phagocytosis assays show thatβ_(1)-AA promotes macrophage migration and phagocytosis.FCM tests suggest thatβ_(1)-AA induces the alteration of M1 rather than M2 markers in macrophages.Finally,the Annexin V/PI assay indicates that macrophage culture supernatants stimulated byβ_(1)-AA cause hepatocyte apoptosis.Overall,these results suggest thatβ_(1)-AA is involved in PBC.Theβ_(1)-AA-induced activation,phagocytosis and phenotypic modification of macrophages may play an important role in the development of hepatic fibrosis and injury. | Ye Wu Xiongxiong Fan Haicun Yu Jingyi Liu Yanru Duan Suli Zhang Li Yan Yunhui Du Huirong Liu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，8： | 1 |
| 4 | The study on compatibility of polymer matrix resins with liquid oxygen显示文摘 | Ge Wang Xiaodong Li Rui Yan Suli Xing | 2006 | Materials Science & Engineering B2006，，1： | 1 |
| 5 | The importance of proleptic branch traits in biomass production of poplar in high-density plantations显示文摘Branch phenotypic traits determine tree crown architecture,which in turn governs leaf display,light interception,and biomass production.Sylleptic and proleptic branches are the obviously different branch phenotypes in the poplar crown.Many studies have focused on the influence of sylleptic branch numbers(SBN)on biomass production,but the research on the influence of proleptic branch phenotypes was only a few.To explore the relationship between proleptic branch traits and biomass generation production in a high-density poplar plantation,we investigated the branch phenotypic traits of three poplar genotypes,all of which have high survival rates in forests(>95%)and significantly different crown architecture and biomass performance in the high-density plantations(1667 stems ha−1).The plantation site was established in 2007.A terrestrial laser scanner was used to measure branch characteristics such as length,angle of origin and termination,and azi-muth angle.A hierarchical cluster analysis performed on branch characteristics showed that SBN,crown depth,and proleptic branch curvature(PBC)were clustered with bio-mass production and leaf area index(LAI).Among all of the monitored traits,PBC played the second most important role in biomass production after SBN and was significantly correlated with SBN,LAI,and biomass production.The positive correlation between PBC and SBN indicated that a larger PBC was associated with more sylleptic branches within the monitored genotypes planted in the high-density plantation,providing greater leaf area and biomass produc-tion.The results of this study will improve the identification of high-production poplar varieties for cultivation in high-density plantations for biofuel production. | Changjun Ding Ningning Wang Qinjun Huang Weixi Zhang Juan Huang Suli Yan Boyi Chen Dejun Liang Yufeng Dong Yingbai Shen Xiaohua Su | 2022 | Journal of Forestry Research2022，33，2： | 1 |
| 6 | The inhibitory effect of BKca channels induced by autoantibodies against angiotensin Ⅱ type 1 receptor is independent of ATIR显示文摘 | Peng Wang Suli Zhang Jie Ren Li Yan Lina Bai Li Wang Pengli Wang Jingwei Bian Xiaochen Yin Huirong Liu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，6： | 1 |
| 7 | Atomically dispersed dual Fe centers on nitrogen-doped bamboo-like carbon nanotubes for efficient oxygen reduction显示文摘Interfacial atomic configuration between dual-metal active species and nitrogen-carbon substrates is of great importance for improving the intrinsic activity of catalysts toward oxygen reduction reaction(ORR).Thus,from the atomic-scale engineering we develop a high intrinsic activity ORR catalyst in terms of incorporating atomically dispersed dual Fe centers(single Fe atoms and ultra-small Fe atomic clusters)into bamboo-like N-doped carbon nanotubes.Benefiting from atomically dispersed dual-Fe centers on the atomic interface of Fe-Nx/carbon nanotubes,the fabricated dual Fe centers catalyst exhibits an extremely high ORR activity(E_(onset)=1.006 V;E_(1/2)=0.90 V),beyond state-of-the-art Pt/C.Remarkably,this catalyst also shows a superior kinetic current density of 19.690 mA·cm^(−2),which is 7 times that of state-of-the-art Pt/C.Additionally,based on the excellent catalyst,the primary Zn-air battery reveals a high power density up to 137 mW·cm^(−2) and sufficient potential cycling stability(at least 25 h).Undoubtedly,given the unique structure–activity relationship of dual-Fe active species and metal-nitrogen-carbon substrates,the catalyst will show great prospects in highly efficient electrochemical energy conversion devices. | Ligang Ma Junlin Li Zhiwei Zhang Hao Yang Xueqin Mu Xiangyao Gu Huihui Jin Ding Chen Senlin Yan Suli Liu Shichun Mu | 2022 | Nano Research2022，15，3： | 0 |
| 8 | Versatile functions of RNA m6A machinery on chromatin显示文摘m6A,a conserved and abundant modification on RNA,regulates RNA processing and function.RNA m6A machinery,including writers,erasers,and readers of m6A,is indispensable for m6A installation and function.Intriguingly,recent studies have revealed that m6A machinery can be recruited to chromatin by pleiotropic factors,including nascent RNA,transcription factors,regulatory RNA,histone modifications,and epigenetic machinery.Consequently,recruitment of m6A machinery can directly regulate chromatin biology,such as transcription,DNA damage repair,and DNA recombination beyond installation of m6A on nascent mRNA.Here,we discuss recent evidence showing that m6A machinery is targeted to chromatin and the direct biological consequences along with the underlying mechanisms. | Tanjing Song Suli Lv Neng Li Xuefeng Zhao Xianyun Ma Yingying Yan Weixia Wang Lidong Sun | 2022 | Journal of Molecular Cell Biology2022，14，3： | 0 |
| 9 | A New Position Calibration Method for MUSER Images显示文摘The Mingantu Spectral Radioheliograph(MUSER),a new generation of solar dedicated radio imagingspectroscopic telescope,has realized high-time,high-angular,and high-frequency resolution imaging of the Sun over an ultra-broadband frequency range.Each pair of MUSER antennas measures the complex visibility in the aperture plane for each integration time and frequency channel.The corresponding radio image for each integration time and frequency channel is then obtained by inverse Fourier transformation of the visibility data.However,the phase of the complex visibility is severely corrupted by instrumental and propagation effects.Therefore,robust calibration procedures are vital in order to obtain high-fidelity radio images.While there are many calibration techniques available—e.g.,using redundant baselines,observing standard cosmic sources,or fitting the solar disk—to correct the visibility data for the above-mentioned phase errors,MUSER is configured with non-redundant baselines and the solar disk structure cannot always be exploited.Therefore it is desirable to develop alternative calibration methods in addition to these available techniques whenever appropriate for MUSER to obtain reliable radio images.In the case where a point-like calibration source contains an unknown position error,we have for the first time derived a mathematical model to describe the problem and proposed an optimization method to calibrate this unknown error by studying the offset of the positions of radio images over a certain period of the time interval.Simulation experiments and actual observational data analyses indicate that this method is valid and feasible.For MUSER’s practical data the calibrated position errors are within the spatial angular resolution of the instrument.This calibration method can also be used in other situations for radio aperture synthesis observations. | Zhichao Zhou Yihua Yan Linjie Chen Wei Wang Suli Ma | 2022 | Research in Astronomy and Astrophysics2022，22，10： | 0 |
| 10 | Valorization of Camellia oleifera oil processing byproducts to value-added chemicals and biobased materials: A critical review显示文摘The C.oleifera oil processing industry generates large amounts of solid wastes,including C.oleifera shell(COS)and C.oleifera cake(COC).Distinct from generally acknowledged lignocellulosic biomass(corn stover,bamboo,birch,etc.),Camellia wastes contain diverse bioactive substances in addition to the abundant lignocellulosic components,and thus,the biorefinery utilization of C.oleifera processing byproducts involves complicated processing technologies.This reviewfirst summarizes various technologies for extracting and converting the main components in C.oleifera oil processing byproducts into value-added chemicals and biobased materials,as well as their potential applications.Microwave,ultrasound,and Soxhlet extractions are compared for the extraction of functional bioactive components(tannin,flavonoid,saponin,etc.),while solvothermal conversion and pyrolysis are discussed for the conversion of lignocellulosic components into value-added chemicals.The application areas of these chemicals according to their properties are introduced in detail,including utilizing antioxidant and anti-in-flammatory properties of the bioactive substances for the specific application,as well as drop-in chemicals for the substitution of unrenewable fossil fuel-derived products.In addition to chemical production,biochar fabricated from COS and its applications in thefields of adsorption,supercapacitor,soil remediation and wood composites are comprehensively reviewed and discussed.Finally,based on the compositions and structural characteristics of C.oleifera byproducts,the development of full-component valorization strategies and the expansion of the appli-cationfields are proposed. | Xudong Liu Yiying Wu Yang Gao Zhicheng Jiang Zicheng Zhao Wenquan Zeng Mingyu Xie Sisi Liu Rukuan Liu Yan Chao Suli Nie Aihua Zhang Changzhu Li Zhihong Xiao | 2024 | Green Energy & Environment2024，9，1： | 0 |
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