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| 1 | 新生儿惊厥的诊断与处理(英文)显示文摘新生儿会发生各种形式的发作性运动,其中有些是癫癎性的惊厥,有些则不是。如何去识别是件困难的事。目前尚缺乏新生儿惊厥诊断与处理的全球性指南。该讲座在全面复习新生儿惊厥的文献并结合作者丰富的临床经验的基础上提出一个处理新生儿惊厥的方案。新生儿惊厥病因很多,缺氧-缺血性脑病和感染是最常见的原因,新生儿中风、遗传代谢病也逐渐被认识。病因是新生儿惊厥结局好坏的主要决定因素。视频-EEG是鉴别癫癎性惊厥与非癫癎惊厥的金标准。苯巴比妥依然是新生儿惊厥的首选药。足量苯巴比妥治疗无效时可考虑使用苯妥英、咪达唑仑或氯硝安定等。顽固性的惊厥,早期可试用吡哆醇、磷酸吡哆醛、叶酸和生物素治疗。对没有惊厥表现的脑电图发作的是否需要治疗有待于进一步的研究。 | Shashikant Subramani SESHIA Richard James HUNTSMAN Noel John LOWRY Mary SESHIA Jerome Yale YAGER Koravangattu SANKARAN 马丽亚 | 2011 | 中国当代儿科杂志2011，13，2： | 9 |
| 2 | Plant-Based Rasayana Drugs from Ayurveda显示文摘Rasayana tantra is one of the eight specialties of Ayurveda.It is a specialized practice in the form of rejuvenative recipes,dietary regimen,special health promoting behaviour and drugs.Properly administered Rasayana can bestow the human being with several benefits like longevity,memory,intelligence,freedom from diseases,youthful age,excellence of luster,complexion and voice,optimum strength of physique and sense organs,respectability and brilliance.Various types of plant based Rasayana recipes are mentioned in Ayurveda. Review of the current literature available on Rasayanas indicates that anti-oxidant and immunomodulation are the most studied activities of the Rasayana drugs.Querying in Pubmed database on Rasayanas reveals that single plants as well as poly herbal formulations have been researched on.This article reviews the basics of Rasayana therapy and the published research on different Rasayana drugs for specific health conditions.It also provides the possible directions for future research. | Subramani Paranthaman Balasubramani Padma Venkatasubramanian Subrahmanya Kumar Kukkupuni Bhushan Patwardhan | 2011 | Chinese Journal of Integrative Medicine2011，17，3： | 6 |
| 3 | Fabrication of Large Area High Density, Ultra-Low Reflection Silicon Nanowire Arrays for Efficient Solar Cell Applications显示文摘垂直地排列的高密度和硅 nanowire (SiNW ) 穿的高方面比率用一个模板和催化蚀刻进程在 Si 底层上被制作了。模板从聚苯乙烯(PS ) 被形成有直径 3050 nm 和密度 1010/cm2 的 nanospheres,由包含 PS 块共聚物的 nanophase 分离生产了。SiNWs 的长度被与 12.5 nm/s 的蚀刻的率改变蚀刻的时间控制。SiNWs 与一个高方面有 biomimetic 结构比率(100 ) ,高密度,和展览极端低的反射。约 0.1% 的极端低的反射比 750 nm 长为 SiNWs 被完成。排列得好的 SiNW/poly (3,4-ethylenedioxy-thiophene ): poly (styrenesulfonate )(PEDOT : PSS ) 异质接面太阳能电池被制作。n 类型硅 nanowire 表面遵守了 PEDOT : 通过一个简单、有效的答案过程形成核心鞘异质接面结构的 PSS。SiNWs 的大表面区域保证了 photogenerated 搬运人的有效收集。没有 nanowire 结构,比作平面房间, SiNW/PEDOT : PSS 异质接面太阳能电池从 0.4% ~ 5.7% 在功率变换效率从 2.35 mA/cm2 在电线走火电流密度展出了增加到 21.1 mA/cm2 和改进。 | Subramani Thiyagu B. Parvathy Devi Zingway Pei | 2011 | Nano Research2011，4，11： | 6 |
| 4 | Cytotoxic and antibacterial substances against multi-drug resistant pathogens from marine sponge symbiont:Citrinin,a secondary metabolite of Penicillium sp.显示文摘Objective:To Isolate,purify,characterize,and evaluate the bioaclive compounds from the sponge-derived fungus Penicillium sp.FF001 and to elucidate its structure.Methods:The fungal strain FF001 with an interesting bioactivity profile was isolated from a marine Fijian sponge Melophlus sp.Based on conidiophores aggregation,conidia development and mycelia morphological characteristics,the isolate FF001 was classically identified as a Penicillium sp.The bioactive compound was identified using various spectral analysis of UV,high resolution electrospray ionization mass spectra,1H and 13C NMR spectral data.Further minimum inhibitory concentrations(MICs)assay and brine shrimp cytotoxicity assay were also carried out to evaluate the biological properties of the purified compound.Results:Bioassay guided fractionation of the EtOAc extract of a static culture of this Penicillium sp.by different chromatographic methods led the isolation of an antibacterial,anticryptococcal and cytotoxic active compound,which was identified as citrinin(1).Further,citrinin(1)is reported for its potent antibacterial activity against methicillin-resistant Staphylococcus aureus(S.aureus),rifampicin-resistant 5.aureus,wild type S.aureus and vancomycin-resistant Enterococcus faecium showed MICs of 3.90,0.97,1.95 and7.81μg/mL,respectively.Further citrinin(1)displayed significant activity against the pathogenic yeast Cryptococcus neoformans(MIC 3.90μg/mL),and exhibited cytotoxicity against brine shrimp larvae LD_(50)of 96μg/mL.Conclusions:Citrinin(1)is reported from sponge associated Penicillium sp.from this study and for its strong antibacterial activity against multi-drug resistant human pathogens including cytotoxicity against brine shrimp larvae,which indicated that sponge associated Penicillium spp.are promising sources of natural bioactive metabolites. | Ramesh Subramani Rohitesh Kumar Pritesh Prasad William Aalbersberg | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，4： | 6 |
| 5 | A novel n-CeO2/n-CdO heterojunction nanocomposite for enhanced photodegradation of organic pollutants under visible light irradiation显示文摘In this study,a series of novel visible light driven n-CeO2/n-CdO heterojunction(CeO2/CdO)nanoco mposites we re successfully fabricated by simple ultrasonication method.Several characte rization tools including X-ray diffraction(XRD),scanning electro n microscopy(SEM),transmission electron microscopy(TEM)and UV-vis diffuse reflectance spectroscopy(UV-DRS),etc.,were utilized to investigate the physicochemical properties of the catalyst and confirm the formation of heterojunction.Under visible light irradiations,the photocatalytic activities of the as-prepared CeO2/CdO nanocomposites were evaluated by degrading of Congo red(CR)and Rhodamine B(RhB)solutions.As a result,the CeO2/CdO(mass percentage ratio 1:3)nanocomposite displays remarkable performance for CR and RhB degradation.The enhancement in the photocatalytic performance of CeO2/CdO(1:3)nanocomposite can be attributed not only to the strong visible-light absorption region,separating the photogenerated electronhole pairs but also to the formation of n-n type heterojunction.The results also indicate that the CeO2/CdO(1:3)nanocomposite has good stabilization and high reusability.In addition,the mechanism is proposed for the coupled semiconductors and possible reasons for the enhancement of visible-light photocatalytic efficiency are also discussed.This work can provide a new gateway to fabricate visible photocatalysts and promising candidate catalysts for poisonous wastewater treatment in the near future. | Karunamoorthy Saravanakumar Subramani Muthupoongodi Velluchamy Muthuraj | 2019 | Journal of Rare Earths2019，37，8： | 6 |
| 6 | Two Distinct Fluorescent Quantum Clusters of Gold Starting from Metallic Nanoparticles by pH-Dependent Ligand Etching显示文摘Two fl uorescent quantum clusters of gold,namely Au25 and Au8,have been synthesized from mercaptosuccinic acid-protected gold nanoparticles of 45 nm core diameter by etching with excess glutathione.While etching at pH~3 yielded Au_(25),that at pH 7-8 yielded Au_(8).This is the fi rst report of the synthesis of two quantum clusters starting from a single precursor.This simple method makes it possible to synthesize well-defined clusters in gram quantities.Since these clusters are highly fl uorescent and are highly biocompatible due to their low metallic content,they can be used for diagnostic applications. | Madathumpady Abubaker Habeeb Muhammed Subramani Ramesh Sudarson Sekhar Sinha Samir Kumar Pal Thalappil Pradeep | 2008 | Nano Research2008，1，4： | 5 |
| 7 | Hesperetin conjugated PEGylated gold nanoparticles exploring the potential role in anti-inflammation and anti-proliferation during diethylnitrosamine-induced hepatocarcinogenesis in rats显示文摘Liver cancer is the fifth most common cancer and one of the leading causes of death in the world, and second most common cause of death in men. Natural products emerge as the most enduring approaches in the development of anticancer targeting drug. Hesperetin(HP), one of the abundant flavonoids found naturally in citrus fruits, has received considerable attention in anti-cancer promotion and progression. The present study was conducted to decipher the role of 0.5 ml hesperetin conjugated gold nanoparticles(Au-m PEG(5000)-S-HP NPs) during diethylnitrosamine(DEN)-induced hepatocarcinogenesis in male Wistar albino rats and shows the better antioxidant that possesses anti-inflammatory,anti-proliferation and anticarcinogenic properties and may modulate signaling pathways.The confirmation of polymer functionalized gold nanoparticles and drug loaded polymer gold nanoparticles were characterized by HR-TEM with EDAX, and DLS with Zeta potential techniques. The drug encapsulation efficiency and release properties were carried out in PBS at pH 7.4 for Au-mPEG(5000)-S-HP and compared with the control pure hesperetin(HP).Here, we review the role of mast cell counts, tumor necrosis factor alpha(TNF-α), transcription factor nuclear factor-κB(NF-κB), levels of glycoconjugates, proliferating cell nuclear antigen(PCNA) and argyrophilic nucleolar organizing regions, are the master regulator of inflammation and proliferation, in the development of hepatocellular injury, liver fibrosis and HCC. DEN-administered animals showed increased mast cell counts, tumor necrosis factor alpha, transcription factor nuclear factor-κB, glycoconjugates, proliferating cell nuclear antigen, and argyrophilic nucleolar organizing regions. Whereas Au-mPEG(5000)-S-HP NPs supplementation considerably suppressed all the above abnormalities. These results suggest that the Au-m PEG(5000)-S-HP NPs exhibited the better potential anticancer activity by inhibiting cell inflammation and proliferation in DEN-induced hepatocellular carcinogenesis. | Gokuladhas Krishnan Jayakumar Subramaniyan Pramila Chengalvarayan Subramani Barath Muralidharan Devaki Thiruvengadam | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，5： | 4 |
| 8 | 结核病的性别差异:南印度某农村地区DOTS项目报告显示文摘背景:南印度 Tiruvallur 地区。目的:了解 14 岁以上成年人在结核感染和患病、就医途径、就医行为、诊断延误、接受 DOT的方便程度、疾病歧视以及治疗依从性等方面的性别差异。方法:相关数据主要来自:1)社区调查,2)在公立初级保健卫生机构(PHIS)主动就医的病人,3)转诊到 PHIS 进行痰涂片检查的可疑结核病人;4)DOTS 策略下的登记报告结核病人。并将社区调查结果与 PHIS 登记病人进行比较。结果:社区人群中 66%的男性和 57%的女性感染了结核菌;男性和女性的涂阳肺结核患病率分别为568/10 万和87/10 万。在 PHIS 就医的男性少于女性,男女之比为 68:100。女性占社区调查发现涂阳病人的 13%;占 PHIS 发现病人的 20%(P<0.05)。随着年龄的增长,男性和女性的登记率显著降低。女性感觉难于与家人讨论自己病情的比例要高于男性(21%∶14%),也更需要有人陪伴去接受 DOT(11%∶6%)。男性的治疗中断率比女性高 1 倍(19%∶8%;P<0.01)。结论:尽管女性发病后更容易遭受歧视和不便,但女性更易于利用医疗服务、接受 DOTS 策略登记以及依从治疗。而男性以及高龄病人在诊断和 DOT服务方面更需要帮助。 | R. Balasubramanian R. Garg T. Santha P. G. Gopi R. Subramani V. Chandrasekaran A. Thomas R. Rajeswari S. Anandakrishnan M. Perumal C. Niruparani G. Sudha K. Jaggarajamma T. R. Frieden P. R. Narayanan 刘小秋 | 2004 | 结核与肺部疾病杂志2004，7，4： | 4 |
| 9 | L-鸟氨酸及其取代衍生物的结构和性质分析(英文)显示文摘L-ornithine is a metabolic product of L-arginine and is found in the liver and other tissues after the enzyme arginase in the urea cycle catalyses the reaction.The presence of L-ornithine has an influence on certain biochemical activities such as the proliferation of collagen production and also has an effect on airway responsiveness.Therefore,it has a role to play in the availability of nitric oxide(NO).A brief reactivity study was carried out for various substituents at the α-C atom of this amino acid.Substituents such as chlorine and fluorine affect the reactivity of the entire molecule and may alter the properties of the amino acid.To understand the properties of molecule,a detailed study was done at the density functional theory(DFT) level and compared with ab initio calculations.Fukui functions were invoked to assess reactivity and stability.The descriptive properties were correlated to logP or pKa using available software to help build a model to quantitatively assess properties and reactivity.Results showed a random reactivity pattern upon halogen substitution and this indicates the need to exercise caution during docking and reactivity studies. | MOHAMED IMRAN P.K SUBRAMANI K | 2009 | 物理化学学报2009，25，11： | 4 |
| 10 | Marine actinomycetes: An ongoing source of novel bioactive metabolites显示文摘 | Ramesh Subramani William Aalbersberg | 2012 | Microbiological Research2012，，10： | 3 |
| 11 | A sulfur self-doped multifunctional biochar catalyst for overall water splitting and a supercapacitor from Camellia japonica flowers显示文摘A versatile use of a sulfur self-doped biochar derived from Camellia japonica(camellia)flowers is demonstrated as a multifunctional catalyst for overall water splitting and a supercapacitor.The native sulfur content in the camellia flower facilitates in situ self-doping of sulfur,which highly activates the camellia-driven biochar(SA-Came)as a multifunctional catalyst with the enhanced electron-transfer ability and long-term durability.For water splitting,an SA-Came-based electrode is highly stable and shows reaction activities in both hydrogen and oxygen evolution reactions,with overpotentials of 154 and 362 mV at 10 mA cm^(−2),respectively.For supercapacitors,SA-Came achieves a specific capacitance of 125.42 F g^(−1)at 2 A g^(−1)and high cyclic stability in a three-electrode system in a 1 M KOH electrolyte.It demonstrated a high energy density of 34.54 Wh kg^(−1)at a power density of 1600 W kg^(−1)as a symmetric hybrid supercapacitor device with a wide working potential range of 0-1.6 V. | Chengkai Xia Subramani Surendran Seulgi Ji Dohun Kim Yujin Chae Jaekyum Kim Minyeong Je Mi-Kyung Han Woo-Seok Choe Chang Hyuck Choi Heechae Choi Jung Kyu Kim Uk Sim | 2022 | Carbon Energy2022，4，4： | 3 |
| 12 | Characterization of a thermostable alkaline protease produced by marine Streptomyces?fungicidicus MML1614显示文摘 | Subramani Ramesh Mahalingam Rajesh Narayanasamy Mathivanan | 2009 | Bioprocess and Biosystems Engineering2009，，6： | 2 |
| 13 | Rectal ulcers and massive bleeding after hemorrhoidal band ligation while on aspirin显示文摘Endoscopic hemorrhoidal band ligation is a well-established nonoperative method for treatment of bleeding internal hemorrhoids(grade 1 to 3). It is a safe and effective technique with a high success rate. Complications with this procedure are uncommon. Although rectal ulceration due to band ligation is a rare complication, it can cause life-threatening hemorrhage especially when patients are on medications which impair hemostasis like aspirin or non steroidal antiinflammatory drugs. We present 2 cases of massive lower gastro-intestinal bleeding in patients who had a band ligation procedure performed 2 wk prior to the presentation and were on aspirin at home. Both the patients were hemodynamically unstable requiring resuscitation. They required platelet and blood transfusions and were found to have rectal ulcers on colonoscopy done subsequently. The rectal ulcers corresponded to the site of band ligation. The use of aspirin by these patients would have caused defects in the hemostasis and may have predisposed them to massive bleeding in the presence of rectal ulcers occurring after the band ligation procedure. Managing aspirin before and after the ligation may be difficult especially since adequate guidelines are unavailable. Stopping aspirin in all the cases might not be safe and the decision should be individualized. | Shruti Patel Ghulamullah Shahzad Kaleem Rizvon Krishnaiyer Subramani Prakash Viswanathan Paul Mustacchia | 2014 | World Journal of Clinical Cases2014，2，4： | 2 |
| 14 | Marine actinomycetes: An ongoing source of novel bioactive metabolites显示文摘 | Ramesh Subramani William Aalbersberg | 2012 | Microbiological Research2012，，10： | 2 |
| 15 | Molecular Recognition at the Liquid-liquid Interface of Colloidal Microcapsules 显示文摘 | Patra D Pagliuca C Subramani C | 2009 | Chem Commun [ J ]2009，，： | 1 |
| 16 | High resistive ferrite films by a solution process for electromagnetic compatible(EMC)devices显示文摘 | SUBRAMANI A K KONDO K TADA M ABE M YOSHIMURA M MATSUSHITA N | 2009 | J Magn Magn Mater2009，321，： | 1 |
| 17 | Thermal decomposition behav- ior of blocked diisocyanates derived from mixture of blocking agents 显示文摘 | Jung Min Lee Subramanis Young Soo Lee | 2005 | Macro- molecular Research2005，13，5： | 1 |
| 18 | Occult splenic rupture with cardiovascular collapse: a report of three cases in critically ill patients显示文摘 | Subramani K Thomas AN Reeve RS | 2002 | Intensive Care Med2002，28，12： | 1 |
| 19 | Chain extension studies of wa- ter-borne polyurethanes from methyl ethyl ketoxime/e-caprolactam- blocked aromatic isocyanates 显示文摘 | Subramani S Cheong I W Kim J H | 2004 | Progress in Organic Coatings2004，51，4： | 1 |
| 20 | Marine actinomyce- tes:an ongoing source of novel bioactive metabolites 显示文摘 | SUBRAMANI R AALBERSBERG W | 2012 | Microbiological Research2012，167，10： | 1 |
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