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19篇 您的检索式:作者名="Strode C"
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1Improved hemostasis with major hepatic resection in the current surgical era显示文摘Background: Major hepatic resection, predominantly performed for oncologic intent, is a complex procedure with the potential for severe intraoperative hemorrhage. The current surgical era has the ability to improve hemostasis throughout the performance of major hepatic resections which decreases blood transfusions and the detrimental effects associated with transfusion. We evaluated hemostasis and outcomes in the current surgical era of performing hepatic resections. Methods: Utilizing the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) database all major hepatic resections performed between 2012 and 2016 were analyzed in regards to hemostasis. Hemostasis was evaluated by the need for and magnitude of blood transfusions. Additional perioperative variables (including operative time, length of hospital stay, and mortality rates) were analyzed to assess for outcomes with hemostasis. The NSQIP results were compared to previous publications involving major hepatic resections to detect improvement in hemostasis and outcomes in the current surgical era. Results: A total of 22777 major hepatic resections met the inclusion criteria for analysis in the NSQIP database. An additional 21198 cases were compiled within the selected publications for comparative analysis. The transfusion rate in the current surgical era was 13.3% versus 38.7% in the previous era ( P = 0.0001). When a transfusion was required in the current surgical era there was a two-fold reduction in the number of units transfused (1.5 U vs. 3.8 U, P = 0.0001). Statistically significant improvements in operative time and length of hospital stay were presented within the current surgical era ( P = 0.0001). When a transfusion was required there was an increased relative risk score of 7 for mortality (4.9% vs. 0.7%, P = 0.0001), however, improvement in mortality rates did not reach statistical significance across surgical eras (1.3% vs. 4.0%, P = 0.0001). Conclusions: The conduction of major hepatic resection in the current surgical era is more hemostatic. Correlated with improved hemostasis are better outcomes for both clinical and financial endpoints. These findings should encourage continued and increased performance of major hepatic resections.Christopher W Mangieri Matthew A Strode Bradley C Bandera 2019Hepatobiliary & Pancreatic Diseases International2019,18,5:3
2The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic- based insecticide resistance in malaria vectors显示文摘DAVID J P STRODE C VONTAS J 2005Proc Natl Acad Sci USA2005,,:1
3Genomic analysis of detoxification genes in the mosquito Aedes aegypti 显示文摘STRODE C WONDJI C S DAVID J P 2008In- sect Biochem Mol Biol2008,38,1:1
4The Anopheles gambiae detoxification chip:A highly specific microarray to study metabolic-based insecticide in malaria vectors 显示文摘DAVID J P STRODE C VONTAS J 2005Proc Natl Acad Sci USA2005,102,11:1
5The Anopheles gambiae detoxification chip : a highly specific microarray to study metabolic-based insecticide in malaria vectors 显示文摘David JP Strode C Vontas J 2005Proc Natl Acad Sci USA2005,102,11:1
6The Anopheles gambiae de- toxification chip: a highly specific microarray to study metabolic- based insecticide resistance in malaria vectors 显示文摘David JP Strode C Vontas J 2005Proc Natl Acad Sci U S A2005,102,11:1
7Genomie analysis of de toxification genes in the mosquito Aedes aegypti 显示文摘Strode C Wondji C S David J P 2008Insect Biochemistry and Molecular Biology2008,38,1:1
8Differential expression of the detoxificatin genes in the different life stages of the ma laria vector Anopheles gambiae显示文摘Strode C Steen K Ortelli F 2006Insect Molecular Biology2006,15,:1
9Cross-induction of detnx- itcation genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti: impact on larval tolerance to chemical in- secticides 显示文摘Poupardin R Reynaud S Strode C 2008Insect Biochem Mol Biol2008,38,5:1
10The Anopheles gambiae detoxificationchip:a highly specific microarray to study metabolic-based insecticide resistance inmalaria vectors显示文摘David JP Strode C Vontas J 2005Proc Natl Acad Sci USA2005,102,11:1
11Genomic analysis of detoxification genes in the mosquito Aedes aegypti显示文摘Strode C Wondji CS David JP 2008Insect Biochem Mol Biol2008,38,1:1
12Genomic Analysis of Detoxification Genes in the Mosquito Aedes Aegypti显示文摘Poupardin R Reynaud S Strode C 2008Insect Biochemistry and Molecular Biology2008,38,1:1
13The Anopheles gambiae detoxi- fication chip: a highly specific mlcroarray to study metabolic-based insecticide resistance in malaria vectors 显示文摘David JP Strode C Vontas J 2005Proc Natl Acad Sci USA2005,102,:1
14Genomic analysis of detoxification genes in the mosquito Aedes aegypti 显示文摘Strode C Wondji CS David JP 2008Insect Biochem Mol Biol2008,38,1:1
15The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic- based insecticide resistance in malaria vectors 显示文摘David JP Strode C VontasJ 2005Proc Natl Acad Sei USA2005,102,11:1
16Evidence of multiple pyrethroid resistance mechanisms in the malaria vector Anopheles gambiae sensu stricto from Nigeria显示文摘AWOLOLA T S ODUOLA O A STRODE C 2009Trans R Soc Trop Med Hyg2009,103,11:1
17The Anopheles gambiae detoxi- fication ehip:a highly specific mieroarray to study metabolic-based insecticide resistance in malaria vectors 显示文摘David J P Strode C Vontas J 2005Proe Natl Acad Sci USA2005,102,11:1
18The anopheles gambiae detoxification chip:A highly specific microarray to study metabolicbased insecticide resistance in malaria vectors显示文摘David JP Strode C Vontas J 2005Genetics2005,102,11:1
19Cross-induction of detoxi- fication genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti : impact on larval tolerance to chemical in- secticide显示文摘Poupardin R Reynaud S Strode C 2008Insect Biochem Mol Biol2008,38,5:1
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