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13篇 您的检索式：作者名="Storek M"

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		题名	作者	年代	出处	被引量
	1	Hematopoietic cell transplantation for Crohn’s disease;is it time?显示文摘AIM: To review all studies in the literature that have assessed Hematopoietic cell transplantation (HCT) and Crohn’s disease (CD) with the ultimate aims of determining if this is a viable treatment option for those with CD. A secondary aim was to review the above literature and determine if the studies shed further light on the mechanisms involved in the pathogenesis of CD. METHODS: An extensive Medline search was performed on all articles from 1970 to 2005 using the ; bone marrow transplant, stem cell, hematopoietic cell, Crohn’s disease and inflammatory bowel disease. RESULTS: We identified one case in which a patient developed CD following an allogeneic HCT from a sibling suffering with CD. Evidence for transfer of the genetic predisposition to develop CD was also identified with report of a patient that developed severe CD following an allogeneic HCT. Following HCT it was found that the donor (that had no signs or symptoms of CD) and the recipient had several haplotype mismatches in HLA class Ⅲ genes in the IBD3 locus including a polymorphism of NOD2/CARD15 that has been associated with CD. Thirty three published cases of patients with CD who underwent either autologous or allogeneic HCT were identified. At the time of publication 29 of these 33 patients were considered to be in remission. The median follow-up time was seven years, and twenty months for allogeneic and autologous HCT respectively.For patients who underwent HCT primarily for treatment of their CD there have been no mortalities related to transplant complications. CONCLUSION: Overall these preliminary data suggest that both allogeneic and autologous HCT may be effective in inducing remission in refractory CD. Thissupports the hypothesis that the hematolymphatic cells play a key role in CD and that resetting of the immune system may be a critical approach in the management or cure of CD.	Y Leung M Geddes J Storek R Panaccione PL Beck	2006	World Journal of Gastroenterology2006，12，41：	5
	2	Factors influencing T -lymphopoiesis after allogeneic hematopoietic cell transplantation显示文摘	JOSEPH A DAWSON M A	2002	Transplantation2002，73，7：	1
	3	Allogeneic peripheral blood stem c ell transplantation may be associated with a high risk of chronic graft-versus -host disease显示文摘	Gooley T Sidak M	1997	Blood1997，90，12：	1
	4	Factors influencing T-lymphopoiesis after allogeneic hematopoietic cell transplantation 显示文摘	Storek J Joseph A Dawson M A	2002	Transplantation2002，73，7：	1
	5	Allogeneic peripheral blood stem cell transplantation may be associated with a high risk of chronic graft-versus-host disease显示文摘	Storek J Gooley T Siadak M	1997	Blood1997，90，12：	1
	6	Safety and pharmacokinetics of the complement inhibitor TT30 in a phase I trial for untreated PNH patients 显示文摘	Risitano AM Storek M Sahelijo L	2015	Blood2015，126，23：	1
	7	Immune reconstitution to cytomegalovirus after allogeneic hematopoietic stem cell transplantation: impact of host factors, drug therapy, and subclinical reactivation显示文摘	Hakki M Riddell SR Storek J	2003	Blood2003，102，8：	1
	8	Reconstitution of the immune system after hematopoietic stem cell transplantation in humans显示文摘	Storek J Geddes M Khan F	2008	Semin Immunopathol2008，30，4：	1
	9	Reconstitution of the immune system after hematopoietic stem cell transplantation in humans 显示文摘	Storek J Geddes M Khan F	2008	Semin Immunopathol2008，30，4：	1
	10	Immune reconstitution after hematopoietic cell transplantation 显示文摘	BOSH M KHAN F M STOREK J	2012	Curr Opin Hematol2012，19，4：	1
	11	Immune recon- stitution after allogeneic marrow transplantation compared with blood stem cell transplantation 显示文摘	STOREK J DAWSON M A STORER B	2001	Blood2001，97，：	1
	12	Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain显示文摘	Storek B Reinhardt M Wang C	2008	Proc Natl Acad Sci USA2008，105，3：	1
	13	Reconstitution of the immune system after hematopoietic stem cell transplantation in humans 显示文摘	Storek J Geddes M Khan F	2008	Semin Immunopathol2008，30，4：	1

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