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3篇 您的检索式：作者名="Stephan Tanner"

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		题名	作者	年代	出处	被引量
	1	Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans : FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture显示文摘	André Bartholome Andreas Kampk?tter Stephan Tanner Helmut Sies Lars-Oliver Klotz	2010	Archives of Biochemistry and Biophysics2010，，1：	1
	2	BAALC, a novel marker of human hematopoietic progenitor cells显示文摘	Claudia D Baldus Stephan M Tanner Donna F Kusewitt Sandya Liyanarachchi Changsun Choi Michael A Caligiuri Clara D Bloomfield Albert de la Chapelle	2003	Experimental Hematology2003，，11：	1
	3	Human iPSC-derived iMSCs improve bone regeneration in mini-pigs显示文摘Autologous bone marrow concentrate(BMC)and mesenchymal stem cells(MSCs)have beneficial effects on the healing of bone defects.To address the shortcomings associated with the use of primary MSCs,induced pluripotent stem cell(iPSC)-derived MSCs(iMSCs)have been proposed as an alternative.The aim of this study was to investigate the bone regeneration potential of human iMSCs combined with calcium phosphate granules(CPG)in critical-size defects in the proximal tibias of mini-pigs in the early phase of bone healing compared to that of a previously reported autograft treatment and treatment with a composite made of either a combination of autologous BMC and CPG or CPG alone.iMSCs were derived from iPSCs originating from human fetal foreskin fibroblasts(HFFs).They were able to differentiate into osteoblasts in vitro,express a plethora of bone morphogenic proteins(BMPs)and secrete paracrine signaling-associated cytokines such as PDGF-AA and osteopontin.Radiologically and histomorphometrically,HFF-iMSC+CPG transplantation resulted in significantly better osseous consolidation than the transplantation of CPG alone and produced no significantly different outcomes compared to the transplantation of autologous BMC+CPG after 6 weeks.The results of this translational study imply that iMSCs represent a valuable future treatment option for load-bearing bone defects in humans.	Pascal Jungbluth Lucas-Sebastian Spitzhorn Jan Grassmann Stephan Tanner David Latz Md Shaifur Rahman Martina Bohndorf Wasco Wruck Martin Sager Vera Grotheer Patric Kropil Mohssen Hakimi Joachim Windolf Johannes Schneppendahl James Adjaye	2019	Bone Research2019，7，4：	0

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