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您的检索式：作者名="Stephan A.Jonker"
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| 1 | Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus显示文摘New hexalobine type alkaloid,5-(200,300-epoxy-300-methylbutyl)-3-(30-hydroxy-30-methyl-10-acetyloxy-but-20-yl)indole(1)alongside the known hexalobines 3-(20,30-dihydroxy-30-methylbutyl)-5-(300-methylcrotonoyl)indole(2),3,5-hexalobine C(3)and 3,5-hexalobine D(4)were isolated from fruits of Hexalobus monopetalus.Compounds 3 and 4 exhibited antifungal activity against Candida albicans. | Hamisi M.Malebo Stephan A.Jonker Reiner Waibel Mayunga H.H.Nkunya | 2014 | Natural Products and Bioprospecting2014，4，2： | 0 |
| 2 | Antifungal Enantiomeric Styrylpyrones from Sanrafaelia ruffonammari and Ophrypetalum odoratum显示文摘Phytochemical investigation of Sanrafaelia ruffonammari Verd and Ophrypetalum odoratum Diels that belongs to the rare genera confined to East African coastal forests led to the isolation of enantiomeric styrylpyrone dimer,(±)-5-methoxy-7-phenyl-[4-methoxy-2-pyronyl]-1-(E)-styryl-2-oxabicyclo-[4.2.0]-octa-4-en-3-one(1)alongside(?)-6-styryl-7,8-epoxy-4-methoxypyran-2-one(2)and the enantiomeric(?)-(3)and(-)-6-styryl-7,8-dihydroxy-4-methoxypyran-2-ones(4).Their structures were established by means of spectroscopic methods.In this paper we reveal for the first time the occurrence of styrylpyrones in East African biodiversity.(?)-6-Styryl-7,8-epoxy-4-methoxypyran-2-one(2)and the dihydroxystyrylpyrone enantiomer(3)showed in vitro antifungal activity against Candida albicans at a concentration of 24.4 and 26.2 lM with zones of inhibition of 17 and 9 mm,respectively.Compound 2 exhibited strong activity in the brine shrimp test with LC50=1.7 lg/mL.Their high cytotoxic and antifungal activities render them candidates for further scientific attention for drug development programs against cancer and microbial infections. | Hamisi M.Malebo Charles Kihampa Clarence A.Mgina Fortunatus Sung’hwa Reiner Waibel Stephan A.Jonker Mayunga H.H.Nkunya | 2014 | Natural Products and Bioprospecting2014，4，2： | 0 |
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