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| 1 | National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed. | Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun | 2012 | World Journal of Gastroenterology2012，18，32： | 8 |
| 2 | Effect of hysteresis on water flow in a sand column with a fluctuating capillary fringe显示文摘 | Lehmann P Stauffer F Hinz C | 1998 | Journal of Contaminant Hydrology1998，33，： | 1 |
| 3 | Linkage of a gene for macular corneal dystrophy to chromosome 16显示文摘 | Vance JM Jaonasson F Lennon F Sarrica J Damji KF Stauffer J | 1996 | Am J Hum Genet1996，58，4： | 1 |
| 4 | Imidazo 显示文摘 | Stauffer F Maira SM Furet P | 2008 | Bioorg Med Cbem Lett2008，18，3： | 1 |
| 5 | Estimation of the evapotranspiration rate from diurnal groundwater level fluctua tions in the Okavango Delta, Botswana显示文摘 | Bauer P Thabeng G Stauffer F | 2004 | Journal of Hydrology2004，288，： | 1 |
| 6 | Habitat selection by birds of ripari- an ommunities: Evaluating effects of habitat alterations 显示文摘 | Stauffer D F Best L B | 1980 | Journal of Wildlife Management1980，44，1： | 1 |
| 7 | Efficient Hopfield pattern recognition on a scale-free neural network显示文摘 | Stauffer D Aharony A Costa L F | 2003 | European Physical Journal B2003，32，3： | 1 |
| 8 | Identification and characterization of NVP-BEZ235,a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity 显示文摘 | Maira SM Stauffer F Brueggen J | 2008 | Mol Cancer Ther2008，7，7： | 1 |
| 9 | Identification and character- ization of NVP-BEZ235, a new orally available dual phosphatidylinos- itol 3-kinase/mammalian target of raparnycin inhibitor with potent in vivo antitumor activity 显示文摘 | Maira SM Stauffer F Brueggen J | 2008 | Mol Cancer Ther2008，7，7： | 1 |
| 10 | Identification and character- Lzation of NVP-BEZ235, a new orally available dual phosphatidylinos- itol 3-kinase/mammalian target of raparnycin inhibitor with potent in Avo antitumor activity 显示文摘 | Maira SM Stauffer F Brueggen J | 2008 | Mol Cancer Ther2008，7，7： | 1 |
| 11 | Retrieval and Interpretative Computer Programs for Mass Spectrometry显示文摘 | Mclafferty F W Stauffer D A | 1985 | J Chem Inf Comput Sci1985，25，3： | 1 |
| 12 | New aro- matase inhibitors from the 3-pyridyl arylether and l-aryl pyrrolo pyridine series显示文摘 | STAUFFER F FURET P FLOERSHEIMER A | 2012 | Bioorg Med Chem Lett2012，22，5： | 1 |
| 13 | Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-10- nase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity 显示文摘 | MAIRA S M STAUFFER F BRUEGGEN J | 2008 | Mol Cancer Ther2008，7，7： | 1 |
| 14 | Identification and characterization of NVP-BEZ235,a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity显示文摘 | Maira SM Stauffer F Brueggen J | 2008 | Mol Cancer Ther2008，7，： | 1 |
| 15 | Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature:implications for clinical imaging显示文摘 | Schnell CR Stauffer F Allegrini PR | 2008 | Cancer Res2008，68，： | 1 |
| 16 | Dynamic gust, landing, and taxi loads determination in the design of the L-1011 显示文摘 | Stauffer W A Hoblit F M | 1973 | Journal of Aircraft1973，10，8： | 1 |
| 17 | Identification and characterization of NVP-BEZ235,a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity显示文摘 | Maira SM Stauffer F Brueggen J | 2008 | Mol Cancer Ther2008，7，7： | 1 |
| 18 | Estimation of the evapotranspiration rate from diurnal groundwater level fluctuations in the Okavango Delta, Botswana显示文摘 | Bauer P Thabeng G Stauffer F | 2004 | Journal of Hydrology2004，288，34： | 1 |
| 19 | Application of advanced methods to design loads determination for the L-1011 transport 显示文摘 | Stauffer W A Lewoh J G Hoblit F M | 1973 | Journal of Aircraft1973，10，8： | 1 |
| 20 | Imidazo quinolines as inhibitors of the PI3K/PKB - pathway 显示文摘 | Stauffer F Maira SM Furet P | 2008 | Bioorg Med Chem Lett2008，18，3： | 1 |
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