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| 1 | Patients with irritable bowel syndrome-diarrhea have lower disease-specific quality of life than irritable bowel syndrome-constipation显示文摘AIM: To determine effect of irritable bowel syndrome(IBS) subtype on IBS-specific quality of life(QOL) questionnaire and its subscales.METHODS: We studied IBS patients visiting our functional gastroenterology disorder clinic at a tertiary care center of Unites States.IBS and IBS subtype were diagnosed using Rome-Ⅲ questionnaire.QOL was assessed using IBS-QOL questionnaire.IBSQOL assesses quality of life along eight subscales: dysphoria,interference with activities,body image,health worry,food avoidance,social reactions,sexual health,and effect on relationships.IBS-QOL and its subscales were both scored on a range of 0-100 with higher scores suggestive of better QOL.Results of overall IBS-QOL scores and subscale scores are expressed as means with 95%CI.We compared mean IBS-QOL score and its subscales among various IBSsubtypes.Analysis of variance(ANOVA) was used to compare the mean difference between more than two groups after controlling for age and gender.A posthoc analysis using Bonferroni correction was used only when P value for ANOVA was less than 0.05.RESULTS: Of 542 patients screened,243 had IBS as per Rome-Ⅲ criteria.IBS-mixed(IBS-M) was the most common IBS subtype(121 patients,49.8%) followed by IBS- diarrhea(IBS-D)(56 patients,23.1%),IBSconstipation(IBS-C)(54 patients,22.2%) and IBSunspecified(IBS-U)(12 patients,4.9%).Overall IBSQOL scores were significantly different among various IBS-subtypes(P = 0.01).IBS-QOL of patients with IBS-D(61.6,95%CI: 54.0-69.1) and IBS-M(63.0,95%CI: 58.1-68.0) was significantly lower than patients with IBS-C(74.5,95%CI: 66.9-82.1)(P = 0.03 and 0.02 respectively).IBS-D patients scored significantly lower than IBS-C on food avoidance(45.0,95%CI: 34.8-55.2 vs 61.1,95%CI: 50.8-71.3,P = 0.04) and interference with activity(59.6,95%CI: 51.4-67.7 vs 82.3,95%CI: 74.1-90.6,P < 0.001).IBS-M patients had more interference in their activities(61.6,95%CI: 56.3-66.9 vs 82.3,95%CI: 74.1-90.6,P = 0.001) and greater impact on their relationships(73.3,95%CI: 68.4-78.2 vs 84.7,95%CI: 77.2-92.2,P = 0.02) than IBS-C patients.Patients with IBS-M also scored significantly lower than IBS-C on food avoidance(47.2,95%CI: 40.7-53.7 vs 61.1,95%CI: 50.8-71.3,P = 0.04) and social reaction(66.1,95%CI: 61.1-71.1 vs 80.0,95%CI: 72.1-87.7,P = 0.005).CONCLUSION: IBS-D and IBS-M patients have lower IBS-QOL than IBS-C patients.Clinicians should recognize food avoidance,effects on daily activities and relationship problems in these patients. | Prashant Singh Kyle Staller Kenneth Barshop Elaine Dai Jennifer Newman Sonia Yoon Shahar Castel Braden Kuo | 2015 | World Journal of Gastroenterology2015，21，26： | 9 |
| 2 | 听力损失及耳鸣的生物工程学解决方案显示文摘现代科技的发展促进了能明显改善听障及耳鸣患者生活质量及交流能力的装置的产生与发展。文章回顾了听力损失及相关的听觉功能障碍的生物工程学解决方案,并对各项技术的未来发展方向作出展望。 | Koch DB Staller S Jaax K Martin E 郑华平(译) 王永华(译) | 2006 | 国际耳鼻咽喉头颈外科杂志2006，30，6： | 1 |
| 3 | Miniemulsion polymerization of aerylated methyl oleate for pressure sensitive adhesives显示文摘 | SHANA BUNKER CHRISTELIE STALLER | 2003 | International Journal of Adhesion&Adhesive2003，23，： | 1 |
| 4 | Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL显示文摘 | Staller P Sulitkova J Lisztwan J | | 0，，6955： | 1 |
| 5 | Chemokine receptor CX-CR4 downregulated by yon Hippel-Lindau tumour suppressor pVHL显示文摘 | Staller P Sulitkova J Lisztwan H | 2003 | Nature2003，425，： | 1 |
| 6 | Miniemulsion Polymerization of Acrylated Methyl Oleate for Pressure Sensitive 显示文摘 | Bunker S Staller C Willenbacher N | 2003 | International Journal of Adhesion Adhesives2003，23，1： | 1 |
| 7 | Mutual requirement of Cdk4 and Myc in malignant transformation: evidence for cyclin D1/Cdk4 and pl6INK4A as upstream regulations of Myc显示文摘 | Haas K Staller P Geisen C | 1997 | Oncogene1997，15，2： | 1 |
| 8 | Miniemulsion polymerization of acrylated methyl oleate for pressure sensitive adhesives 显示文摘 | Shana Bunker Christelle Staller Norbert Willenbacher | 2003 | International Journal of Adhesion and Adhesives2003，23，1： | 1 |
| 9 | International journal of adhesion adsheives,miniemulsion polymerization of acrylated methyl oleate for pressure sensitive adhesives显示文摘 | Christelle Staller | 2003 | Norbert Willenbacher and Richard Wool2003，23，1： | 1 |
| 10 | Chemokine receptor CX-CR4 downregulated by von Hippel-Lindau tumour suppressorpVHL显示文摘 | Staller P Sulitkova J Lisztwan J | 2003 | Nature2003，425，6955： | 1 |
| 11 | Chemokine receptor CXCR4 downregul ated by von Hippel-Lindau tumour suppressor pVHL显示文摘 | Staller P Sulitkova J Lisztwan J | 2003 | Nature2003，425，6955： | 1 |
| 12 | Control of cell proliferation by Myc显示文摘 | Bouchard C Staller P Eilers M | 1998 | Trends Cell Biol1998，8，： | 1 |
| 13 | Migration of sternal wire into ascending aorta显示文摘 | Hazelrigg SR Staller B | 1994 | Ann Thorac Surg1994，57，4： | 1 |
| 14 | Pediatric outcomes with nucleus 24 contour;north american clinical trial显示文摘 | staller S Parkinson A Arcaroli J | 2002 | Ann Otol Rhinol Laryngol2002，189，3： | 1 |
| 15 | Miniemusion polymerization of acrylated methyl oleate for pressure sensitive adhesives显示文摘 | BUNKER S STALLER C WILLENBACHER N | 2003 | International Journal of Adhesion &Adhesive2003，23，1： | 1 |
| 16 | Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL显示文摘 | Staller P Sulitkova J Lisztwan J | 2003 | Nature2003，425，： | 1 |
| 17 | Chemokiue receptor CXCR4 downregulated by yon Hippel- Lindautumour suppressor pVHL 显示文摘 | Staller P Sulitkova J Lisztwan J | 2003 | Nature2003，425，6955： | 1 |
| 18 | Star Tracker with Regional Electronic Shutter 显示文摘 | YADID-PECHT O PAIN CMOS Active Pixel Sensor B STALLER C | 1997 | IEEE Journal of Solid-State Circuits1997，32，2： | 1 |
| 19 | Chemokine receptor CXCR4 downregulated by yon Hippel-Lindau turnout suppressor pVHL 显示文摘 | Staller P Sulitkova J Lisztwan J | 2003 | Nature2003，425，6955： | 1 |
| 20 | Chemokine receptor CXCR4 downregulated by von Hippel-Iindau tumour suppressor pVHL显示文摘 | Staller P Sulitkova J Lisztwan J | 2003 | Nature2003，，425： | 1 |
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