|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification and primary genetic analysis of Arabidopsis stomatal mutants in response to multiple stresses显示文摘In response to variable environmental conditions, guard cells located in the leaf epidermis can integrate and cope with a multitude of complicated stimuli, thereby making stomata in an appro- priate state. However, many signaling components in guard cell signaling remain elusive. In our laboratory, a tool for non-invasive remote infrared thermal images was used to screen an ethyl methane sulfonate-mutagenized population for Arabidopsis stomatal response mutants under multiple stresses (ABA, H2O2, CO2, etc.). More than forty 'hot' or 'cold' mutants were isolated (above or below 0.5℃ in con- trast to normal plantlets). Identification and primary genetic analysis of these mutants show that they are monogenic recessive mutations and there exist distinct difference in stomata apertures compared to wild type. These mutants in response to various environmental stresses and hormones were comprehen- sively investigated, which enables us to further un- derstand the cross-talk in different signal transduction pathways. | SONG Yuwei KANG Yanli LIU Hao ZHAO Xiaoliang WANG Pengtao AN Guoyong ZHOU Yun MIAO Chen SONG Chunpeng | 2006 | Chinese Science Bulletin2006，51，21： | 11 |
| 2 | 血清CA19-9水平可能做为非小细胞肺癌转移的一个指标(英文)显示文摘Objective:The aim of our study was to evaluate the serum levels of CA19-9 in patients with non-small cell lung cancer(NSCLC)and to analyze the relationship between serum levels of CA19-9 and metastasis.Methods:Serum levels of CA19-9 in 1200 NSCLC patients from February 2006 to August 2011 were evaluated retrospectively.The relationship between serum levels of CA19-9 and sites of metastasis were analyzed.Results:Of the 1200 patients,528 were stage IV and the positive rate of CA19-9 was 32%(169 cases)and 288 stage III,positive rate 20%(58 cases);144 stage II,positive rate 12%(17 cases);240 stage I,positive rate 3%(7 cases).There were statistical differences from stage I to stage IV(P<0.01).The total positive rate in the 1200 cases was 21%.Furthermore,of the 528 stage IV cases,350 had bone metastasis and the positive rate of CA19-9 was 43%(150 cases)in bone metastatic cases.In turn,in CA19-9 positive patients(169 cases)of stage IV, the positive rate of bone metastasis was 89%(150/169).There was no statistical difference of positive rate of CA19-9 between adenocarcinoma and squamous carcinoma(P>0.05).Conclusion:Positive rate of CA19-9 increases accordingly from stage I to stage IV.The serum levels of CA19-9 may be as an indicator for metastases in patients with NSCLC,especially for bone metastasis in stage IV diseases. | Xing'an Liu Guoyong Shan Song Zhang Kaijian Lei | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，12： | 1 |
| 3 | An efficient procedure for protection of carbonyls catalyzed by sulfamic acid 显示文摘 | Wang Bo Gu Yanlong Song Guoyong | 2005 | J Mol Catal2005，233，： | 1 |
| 4 | An efficient procedure for protection of carbonyls catalyzed by sulfamic acid显示文摘 | Wang Bo Gu Yanlong Song Guoyong | 2005 | Journal of Molecular Catalysis A:Chemical2005，233，： | 1 |
| 5 | The involvement of a P38-like MAP kinase in ABA-induced and H2O2-mediated stomatal closure in Vicia faba L.显示文摘 | Jing Jiang Pengtao Wang Guoyong An Pengcheng Wang Chun-Peng Song | 2008 | Plant Cell Reports2008，，2： | 1 |
| 6 | Iridium abnormal N-heterocyclic earbene complexes via highly selective C-H activation 显示文摘 | SONG Guoyong WANG Xinjiao LI Yongxin | 2008 | Organometall2008，27，6： | 1 |
| 7 | A novel ABCD1 G1202A mutation in a Chinese patient with pure adrenomyeloneuropathy and literature review显示文摘Adrenomyeloneuropathy(AMN)is a kind of varied disease caused by ABCD1 gene mutation and characterized by very-long-chain fatty acids(VLCFA)accumulation.It is diag-nosed by clinical features,high VLCFAs levels and ABCD1 gene mutation.AMN is rarely reported in Chinese population.In this study,we report the genetic and clinical features of a Chinese pure AMN patient.Meanwhile,we conducted a literature review of AMN cases to summarize the characteristics of AMN.We report a rare Chinese pure AMN case with slowly progressive weakness of the lower extremities,caused by a novel c.1202G>A mutation in ABCD1 gene.The literature review indicates that spastic paraplegia is the mainly clinical manifestation in patients with AMN.VLCFAs and ABCD1 gene test should be performed in patients with spastic paraplegia of the lower limbs to diagnose AMN. | Yu Zhang Guoyong Zhang Wenhui Chen Zheng Pu Lu Song Xinghua Tang Zhenguo Liu | 2021 | Genes & Diseases2021，8，5： | 0 |
| 8 | Epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China:a hospital-based retrospective study显示文摘Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death.China has the largest population of patients with traumatic spinal cord injury.Previous studies of traumatic spinal cord injury in China have mostly been regional in scope;national-level studies have been rare.To the best of our knowledge,no national-level study of treatment status and economic burden has been performed.This retrospective study aimed to examine the epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China at the national level.We included 13,465 traumatic spinal cord injury patients who were injured between January 2013 and December 2018 and treated in 30 hospitals in 11 provinces/municipalities representing all geographical divisions of China.Patient epidemiological and clinical features,treatment status,and total and daily costs were recorded.Trends in the percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department and cost of care were assessed by annual percentage change using the Joinpoint Regression Program.The percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department did not significantly change overall(annual percentage change,-0.5%and 2.1%,respectively).A total of 10,053(74.7%)patients underwent surgery.Only 2.8%of patients who underwent surgery did so within 24 hours of injury.A total of 2005(14.9%)patients were treated with high-dose(≥500 mg)methylprednisolone sodium succinate/methylprednisolone(MPSS/MP);615(4.6%)received it within 8 hours.The total cost for acute traumatic spinal cord injury decreased over the study period(-4.7%),while daily cost did not significantly change(1.0%increase).Our findings indicate that public health initiatives should aim at improving hospitals’ability to complete early surgery within 24 hours,which is associated with improved sensorimotor recovery,increasing the awareness rate of clinical guidelines related to high-dose MPSS/MP to reduce the use of the treatment with insufficient evidence. | Hengxing Zhou Yongfu Lou Lingxiao Chen Yi Kang Lu Liu Zhiwei Cai David BAnderson Wei Wang Chi Zhang Jinghua Wang Guangzhi Ning Yanzheng Gao Baorong He Wenyuan Ding Yisheng Wang Wei Mei Yueming Song Yue Zhou Maosheng Xia Huan Wang Jie Zhao Guoyong Yin Tao Zhang Feng Jing Rusen Zhu Bin Meng Li Duan Zhongmin Zhang Desheng Wu Zhengdong Cai Lin Huang Zhanhai Yin Kainan Li Shibao Lu Shiqing Feng | 2024 | Neural Regeneration Research2024，19，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员