2篇
您的检索式：作者名="Solomon Rotimi"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Evaluation of antioxidant enzymes performances and DNA damage induced by bisphenol A and diisobutylphthalate in Hyperiodrilus africanus-earthworms显示文摘Background:Bisphenol A(BPA)and diisobuthylphthalate(DIBP)have found wide applications as plasticizers;however,they are covalently bonded to materials and are subsequently leached into the environment.Methods:This study evaluated the effects of BPA,DIBP and mixtures of BPA and DIBP on the antioxidant enzymes[superoxide dismutase(SOD),peroxidase(POD)]activities using standard methods and DNA profile of earthworm(Hyperiodrilus africanus)using randomly amplified polymerase chain reaction(RAPD-PCR)method.A total of 2 kg soil samples collected from FADAMA Farm,Federal University of Agriculture,Abeokuta were spiked to obtain 1,2.5,5 and 10 ppm of BPA,DIBP and mixtures of BPA and DIBP.Earthworms were exposed to the unpolluted and spiked soil samples and were collected on the 7th and 14th day for SOD,POD and DNA analysis.Results:SOD activity was more pronounced at 5 and 10 ppm concentrations.POD activity was increased in all concentrations,including the control,meanwhile POD activity induced by BPA and DIBP was significantly higher(p<0.05)at 10 ppm compared to other concentrations.RAPD-PCR analysis revealed varying DNA fragment lengths due to excessive oxidative stress generated by the treatments,resulting in DNA damage.BPA and DIBP mixtures generated more fragments of DNA on day 14 than other treatments.Conclusions:This study established that antioxidant activity decreases with exposure time to BPA and DIBP,while DNA damage increases with exposure time. | Olanrewaju Olujimi Rhoda Ayoola Oluwafunmilayo Olayinka Oluwatosin Dosumu Solomon Rotimi Adeyinka Aladesida | 2020 | Emerging Contaminants2020，6，1： | 0 |
| 2 | Mathematical modeling of malaria transmission dynamics in humans with mobility and control states显示文摘Malaria importation is one of the hypothetical drivers of malaria transmission dynamics across the globe.Several studies on malaria importation focused on the effect of the use of conventional malaria control strategies as approved by the World Health Organization(WHO)on malaria transmission dynamics but did not capture the effect of the use of traditional malaria control strategies by vigilant humans.In order to handle the aforementioned situation,a novel system of Ordinary Differential Equations(ODEs)was developed comprising the human and the malaria vector compartments.Analysis of the system was carried out to assess its quantitative properties.The novel computational algorithm used to solve the developed system of ODEs was implemented and benchmarked with the existing Runge-Kutta numerical solution method.Furthermore,simulations of different vigilant conditions useful to control malaria were carried out.The novel system of malaria models was well-posed and epidemiologically meaningful based on its quantitative properties.The novel algorithm performed relatively better in terms of model simulation accuracy than Runge-Kutta.At the best model-fit condition of 98%vigilance to the use of conventional and traditional malaria control strategies,this study revealed that malaria importation has a persistent impact on malaria transmission dynamics.In lieu of this,this study opined that total vigilance to the use of the WHO-approved and traditional malaria management tools would be the most effective control strategy against malaria importation. | Gbenga Adegbite Sunday Edeki Itunuoluwa Isewon Jerry Emmanuel Titilope Dokunmu Solomon Rotimi Jelili Oyelade Ezekiel Adebiyi | 2023 | Infectious Disease Modelling2023，8，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员