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| 1 | Age distribution,polyps and rectal cancer in the Egyptian population-based cancer registry显示文摘AIM:To describe the clinical and epidemiologic profiles of the disease and to compare the findings with those generated from the previous hospital-based studies.METHODS:The Gharbiah cancer registry is the only population-based cancer registry in Egypt since 1998.We analyzed the data of all colorectal cancer patients included in the registry for the period of 1999-2007.All medical records of the 1364 patients diagnosed in Gharbiah during the study period were retrieved and the following information abstracted:age,residence,diagnosis date,grade,stage,topology,clinical characteristics,and histology variables.Egyptian census data for 1996 and 2006 were used to provide the general population's statistics on age,sex,residence and other related demographic factors.In addition to age-and sex-specific incidence rate analyses,we analyze the data to explore the incidence distribution by rural-urban differences among the 8 districts of the province.We also compared the incidence rates of Gharbiah to the rates of the Surveillance Epidemiology and End Results(SEER) data of the United States.RESULTS:Over the 9 year-period,1364 colorectal cancer cases were included.The disease incidence under age 40 years was relatively high(1.3/10 5) while the incidence in the age groups 40 and over was very low(12.0/10 5,19.4/10 5 and 21.2/10 5 in the age groups 40-59 years,60-69 years and > 70 years,respectively).The vast majority of tumors(97.2%) had no polyps and 37.2% of the patients presented with primary lesions in the rectum.Colorectal cancer was more common in patients from urban(55%) than rural(45%) areas.Regional differences in colon and rectal cancer incidence in the 8 districts of the study province may reflect different etiologic patterns in this population.The registry data of Egypt shows a slightly higher incidence of colorectal cancer than the United States in subjects under age 40 years.The results also shows significantly lower incidence of colorectal cancer in subjects over age 40 years compared to the same age group in the United States SEER.CONCLUSION:Low rate of polyps,low incidence in older subjects,and high rate of rectal cancer in Egypt.Future studies should explore clinical and molecular disease patterns. | Darlene Veruttipong Amr S Soliman Samuel F Gilbert Taylor S Blachley Ahmed Hablas Mohamed Ramadan Laura S Rozek Ibrahim A Seifeldin | 2012 | World Journal of Gastroenterology2012,18,30: | 12 |
| 2 | Magnitude of modulation of gene expression in aneuploid maize depends on the extent of genomic imbalance显示文摘Aneuploidy has profound effects on an organism,typically more so than polyploidy,and the basis of this contrast is not fully understood.A dosage series of the maize long arm of chromosome 1(1L)was used to compa re relative global gene expression in diffe rent types and degrees of aneuploidy to gain insights into how the magnitude of genomic imbalance as well as hypoploidy affects global gene expression.While previously available methods require a selective examination of specific genes,RNA sequencing provides a whole-genome view of gene expression in aneuploids.Most studies of global aneuploidy effects have concentrated on individual types of aneuploids because multiple dose aneuploidies of the same genomic region are difficult to produce in most model genetic organisms.The genetic toolkit of maize allows the examination of multiple ploidies and 1-4 doses of chromosome arms.Thus,a detailed examination of expression changes both on the varied chromosome arms and elsewhere in the genome is possible,in both hypoploids and hyperploids,compared with euploid controls.Previous studies observed the inverse trans effect,in which genes not varied in DNA dosage were expressed in a negative relationship to the varied chromosomal region.This response was also the major type of changes found globally in this study.Many genes varied in dosage showed proportional expression changes,though some were seen to be partly or fully dosage compensated.It was also found that the effects of aneuploidy were progressive,with more severe aneuploids producing effects of greater magnitude. | Adam F·Johnson Jie Hou Hua Yang Xiaowen Shi Chen Chen Md Soliman Islam Tieming Ji Jianlin Cheng James A·Birchler | 2020 | Journal of Genetics and Genomics2020,47,2: | 3 |
| 3 | An investigation of the forces on three dimensional bluff bodies in rough wall turbulent boundary layers显示文摘 | Lee B E Soliman B F | 1977 | Journal of Fluids Engineering1977,97,: | 2 |
| 4 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017,25,2: | 2 |
| 5 | CD15(Leu M1)immunoreactivily:prognostic factor for sporadic and hereditary medullary thyroid cancer显示文摘 | Langle F Soliman T Neuhold N | 1994 | WorldJ Surg1994,18,4: | 1 |
| 6 | The Wadi Natrum: chemical composition and microbial mass developments in alkaline brines of eutrophic desert lakes 显示文摘 | Imhoff J F Sahl H G Soliman G S H | 1979 | Geomicrob J1979,1,: | 1 |
| 7 | A genetic variant BDNF polymorphism aters extinction learning in both mouse and human 显示文摘 | Soliman F Glatt CE Kevin G | 2010 | Science2010,327,5967: | 1 |
| 8 | Effects of enhancing mitochondrial oxidative phosphorylation with reducing equivalents and ubiquinone on 1-methyl-4-phenylpyridinium toxicity and complex I-IV damage in neuroblastoma cells 显示文摘 | MAZZIO E A SOLIMAN K F A | 2004 | Biochem Pharmacol2004,67,9: | 1 |
| 9 | Limiting shear creep of epoxy adhesive at the FRP-concrete interface using muhi- walled carbon nanotubes显示文摘 | Soliman E Kandil U F Taha M R | 2012 | Intemational Journal of Adhesion and Adhesives2012,33,: | 1 |
| 10 | Modeling and querying possible repairs in duplicate detection 显示文摘 | Beskales G Soliman M A Ilyas I F | 2009 | Proceedings of the VLDB Endowment2009,2,1: | 1 |
| 11 | Ship stability criteria based on chaotic transients from incursive fractals 显示文摘 | Thompson J M T Rainey F C T Soliman M S | 1995 | Philosophical Transactions of the Royal Society1995,332,1: | 1 |
| 12 | Influence of paraffin wax characteristics on the formulation of wax- based binders and their debinding fromgreen molded parts using two comparative techniques 显示文摘 | Zaky M T Soliman F S Farag A S | 2009 | J Mater Proc Techn2009,209,1819: | 1 |
| 13 | PD-L1 expression is in- creased in a subset of basal type breast cancer cell 显示文摘 | SOLIMAN H KHALIL F ANTONIA S | 2014 | PLoS 0ne2014,9,88: | 1 |
| 14 | The Wadi Natrun: Chemical composition and microbial mass developments in alkaline brines of Eutrophic Desert Lakes显示文摘 | Imhoff J F Sahl H G Soliman G S H | 1979 | GeomicrobiologyJournal1979,,3: | 1 |
| 15 | The Wadi Natrun : chemical composition and microbial mass developments in alkaline brines of eutrophic desert lakes显示文摘 | Imhoff J F Sahl H G Soliman G S H | 1979 | Geomicrob J1979,1,3: | 1 |
| 16 | In vitro screening for the tumo- ricidal properties of international medicinal herbs 显示文摘 | Mazzio E A Soliman K F | 2009 | Phytother Res2009,23,3: | 1 |
| 17 | Oxidation resistance of the aluminide coatingformed on carbon steels显示文摘 | SOLIMAN H M MOHAMED K E ABDEI-AZIM M E HAMMAD F H | 1997 | Journal of Materials Science&Technology1997,13,: | 1 |
| 18 | Frequency distribution of void ratio of granular materials determined by an image analyzer 显示文摘 | BHATIA S K SOLIMAN A F | 1990 | Soils and Foundations1990,30,1: | 1 |
| 19 | Efficient search for the top-k probable nearest neighbors in uncertain databases 显示文摘 | Bekales G Soliman M A Ilyas I F | 2008 | Proc of the VLDB Endowment2008,1,1: | 1 |
| 20 | Clinical characterization and NPHP1 mutations in nephronophthisis and as- sociated ciliopathies: a single center experience 显示文摘 | SOLIMAN N A HILDEBRANDT F OTTO E A | 2012 | Saudi J Kidney Dis Transpl2012,23,5: | 1 |