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| 1 | Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease: Responders versus nonresponders显示文摘瞄准:探索直肠的氮的氧化物(没有) 作为处理的简历标记,在 ulcerative (UC ) 和 Crohn 的反应是疾病(CD ) ,并且检验在之间的关系直肠没有,没有 synthases (NOS ) 的粘膜表示,和支持 inflammatory cytokines。方法:有 UC 的 22 个病人并且 24 在类固醇治疗期间与 CD 被监视。直肠没有层次被测量,临床的活动在天被估计 1, 3, 7 和 28。NOS 和支持 inflammatory cytokines 的粘膜存在被免疫组织化学和 RT-PCR 分析。结果:显著地显示的活跃 UC 和 CD 增加了直肠没有层次(10950 +/- 1280 每十亿分开的 7610 和 5040 +/-(ppb ) ,分别地) 作为与控制相比(154 +/- 71 ppb, P <
0.001 ) 。直肠不在 UC 和 CD 与疾病活动微弱地相关(r = 0.34 为 UC 和 r = 0.48 为 CD, P <
0.01 ) 。在 12 个病人,一堂类固醇倔强的功课导致了结肠切除术。仅仅稍微有的这些病人没增加层次(UC:620 +/- 270 ppb;CD:1260 +/- 550 ppb ) 与那些相比与治疗学的回答(UC:18860 +/- 530 ppb, P <
0.001;CD:10060 +/- 3200 ppb, P <
0.05 ) 。结论:直肠没有水平是在是的 IBD 的治疗反应的一个有用简历标记低没有层次预言差的临床的回答到类固醇治疗。 | Tryggve Ljung Sofie Lundberg Mark Varsanyi Catharina Johansson Peter T Schmidt Max Herulf Jon O Lundberg Per M Hellstr(o|¨)m | 2006 | World Journal of Gastroenterology2006,12,21: | 10 |
| 2 | Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry显示文摘Background In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan- Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77–470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48–68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41–2657.01). Conclusions The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients. | Martijn S.van Mourik Nathalie van der Velde Giulio Mannarino Marie-Pierre Thibodeau Jean-Bernard Masson Gennaro Santoro Jan Baan Sofie Jansen Jana Kurucova Martin Thoenes Cornelia Deutsch ANDreas W.Schoenenberger ANDrea Ungar Peter Bramlage M Marije Vis | 2019 | Journal of Geriatric Cardiology2019,16,6: | 3 |
| 3 | Engineering properties of inorganic polymer concretes (IPCs)显示文摘 | M Sofi J S J van Deventer P A Mendis | 2007 | Cement and Concrete Research2007,37,: | 1 |
| 4 | A signal for an abuse liability for pregabalin—results from the Swedish spontaneous adverse drug reaction reporting system显示文摘 | Sofie Schwan Anders Sundstr?m Elisabet Stjernberg Ebba Hallberg P?r Hallberg | 2010 | European Journal of Clinical Pharmacology2010,,9: | 1 |
| 5 | Engineering Properties of Inorganic Polymer Concretes (IPCs)显示文摘 | Sofi M Deventer J S J Mendis P A | 2007 | Cement and Concrete Research2007,37,: | 1 |
| 6 | Engineering properties of inorganic polymer concretes (IPCs)显示文摘 | SOFI M DEVENTER J S J VAN MENDIS P A | 2007 | Cem Concr Res2007,37,: | 1 |
| 7 | Utilizing bupreorphine - naloxone to treat illicit and prescription - opioid dependence 显示文摘 | Sofie M Roonald F Kathryn G | 2014 | Neuro- psychiatric Disease and Treatment2014,10,: | 1 |
| 8 | Engineering properties of inorganic polymer concretes(IPCs)显示文摘 | Sofi M Van Deventer b Mendis P A | 2007 | Cement and Concrete Research2007,,37: | 1 |
| 9 | Postprocedural hyper- glycemia in ST elevation myocardial infarction submitted to percutaneous coronary intervention: a prognostic indi- cator and a marker of metabolic derangement显示文摘 | Lazzeri C Chiostri M Sofi A | 2010 | J Card- iovasc Med ( Hagerstown)2010,11,1: | 1 |
| 10 | Engineering properties of inorganic polymer concretes(IPCs)显示文摘 | Sofi M Van Deventer J S J Mendis P A | 2007 | Cement and Concrete Research2007,37,2: | 1 |
| 11 | Nonstationary re- sponse envelope probability densities of nonlinear oscil- lators 显示文摘 | SPANOS P D SOFI A PAOLA M D | 2007 | Journal of Applied Mechanics2007,74,2: | 1 |
| 12 | Engineering Properties of Inorganic Polymer Concretes (IPCs) 显示文摘 | Sofi M Van Deventer J S J Mendis P A | 2007 | Cement and Concrete Research2007,37,: | 1 |
| 13 | Influence of ambient temperature on early age concrete behaviour of anchorage zones显示文摘 | Sofi M Mendis P Baweja D | 2014 | Construction and Building Materials2014,53,4: | 1 |
| 14 | Approximate solution of the Fokker-Planck-Kolmogorov equation显示文摘 | SOFI A | 2002 | Prob Eng Mech2002,17,: | 1 |
| 15 | Nonstationary response envelope probability densities of nonlinear oscillators显示文摘 | Spanos P D Sofi A Di Paola M | 2007 | Journal of Applied Mechanics2007,74,: | 1 |
| 16 | Nonstationary response envelope probability densities of nonlinear oscillators 显示文摘 | Spanos P D Sofi A Di Paola M | 2007 | Journal of Applied Mechanics2007,74,2: | 1 |
| 17 | Metabolic programming in dendritic cells tailors immune responses and homeostasis显示文摘It is being increasingly acknowledged that immune cells depend on certain metabolic traits to perform their functions and that the extracellular environment can influence cell metabolism and vice versa.Dendritic cell(DC)subsets traffic through highly diverse environments from the bone marrow,where they develop,to the various peripheral tissues,where they differentiate and capture antigens,before they migrate to the lymph node to present antigens and prime T cells.It is plausible that DC subsets modulate their stimulatory abilities in response to unique metabolic programming.The metabolic requirements of DCs are just recently being discovered,and subset-and context-specific metabolic phenotypes in DCs are highly intertwined with DC functions.In this review,we present the current knowledge on the intrinsic and extrinsic determinants of DC metabolism,how they regulate DC function with examples from tumor biology and in interaction with the microbiota,and discuss how this can be applied therapeutically. | Sofie Hedlund Møller Limei Wang Ping-Chih Ho | 2022 | Cellular & Molecular Immunology2022,19,3: | 1 |
| 18 | Frequent periodic leg movement during sleep is associated with left ventricular hy- pertrophy and adverse cardiovascular outcomes显示文摘 | Mirza M Shen WK Sofi A | 2013 | J Am Soc Echocardiogr2013,26,7: | 1 |
| 19 | Influence of high temperature on end-of-season tundra CO2 exchange显示文摘 | SOFIE M IVAN N MARK H | 2001 | Ecosystems2001,4,3: | 1 |
| 20 | Effect of amlodipine and lisinopril on microalbuminuria in patients with essential hypertension: a prospective study显示文摘 | Jalal S Sofi FA Abass S M | 2010 | Indian J Nephrol2010,20,1: | 1 |