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1篇 您的检索式:作者名="Soad M.Toaima"
    题名 作者 年代 出处 被引量
1Astragalus kahiricus根提取物对乙醇诱导的大鼠肝细胞凋亡的肝保护作用(英文)显示文摘The hepatoprotective activity of the ethanol extract of Astragalus kahiricus(Fabaceae) roots against ethanol-induced liver apoptosis was evaluated and it showed very promising hepatoprotective actions through different mechanisms.The extract counteracted the ethanol-induced liver enzymes leakage and glutathione depletion.In addition,it demonstrated anti-apoptotic effects against caspase-3 activation and DNA fragmentation that were confirmed by liver histopathological examination.Moreover,the phytochemical study of this extract led to the isolation of four cycloartane-type triterpenes identified as astrasieversianin II(1),astramembrannin II(2),astrasieversianin XIV(3),and cycloastragenol(4).The structures of these isolates were established by HRESI-MS and 1D and 2D NMR experiments.The antimicrobial,antimalarial,and cytotoxic activities of the isolates were further evaluated,but none of them showed any activity.Rasha M.Allam Dina A.Selim Asser I.Ghoneim Mohamed M.Radwan Salwa M.Nofal Amani E.Khalifa Ola A.Sharaf Soad M.Toaima Aya M.Asaad Nadia A.El-Sebakhy 2013中国天然药物2013,11,4:0
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