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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Improvement of Regeneration of Jycopersicon Pennelli Protoplasts by Decreasing Ethylene Production显示文摘 | Jansen C E Snel E A M | 1991 | Plant Cell Report1991，9，： | 1 |
| 3 | The us of chlorophyll fluores- cence nomenclalure in Dlant stress physiology 显示文摘 | Van kooten O Snel JFH | 1990 | Ptoto- synth Research1990，25，3： | 1 |
| 4 | In vivo analysis of carpal kin-ematics and comparative review of the literature显示文摘 | Moojen TM Snel JG Ritt MJ et a1 | | 0，，： | 1 |
| 5 | Comparative assessment of largescale data sets of protein-protein interactions显示文摘 | von Mering C Krause R Snel B | 2002 | Nature2002，417，： | 1 |
| 6 | Long-term omeprazole treatment in resistant gastroesophageal reflux disease:efficacy,safety,and influence on gastric mucosa显示文摘 | Klinkenberg-Knol EC Nelis F Dent J Snel P Mitchell B Prichard P | 2000 | Gastroenterology2000，118，： | 1 |
| 7 | The genomesequence of Bifidobacterium longum reflects its adaptation to thehuman gastrointestinal tract 显示文摘 | Schell M A Karmirantzou M Snel B | 2002 | Proc Natl Acad Sci USA2002，99，14： | 1 |
| 8 | Pectus excavatum reconstruction with silicone implants:long-term results and a review of the english-lan- guage literature显示文摘 | Snel B J Spronk CA Werker PM | 2009 | Ann Plast Surg2009，62，2： | 1 |
| 9 | The use of chlorophyll fluorescence nomenclature in plant stress physiology显示文摘 | Kooten O V Snel J F H | 1990 | Photosynthesis Research1990，25，3： | 1 |
| 10 | The use of chlorophyll fluorescence nomenclature in plant stress physiology显示文摘 | Van Kooten O Snel J F H | 1990 | Photosynthesis Research1990，25，： | 1 |
| 11 | Risk factors for hemiplegic shoulder pain:A systematic review显示文摘 | Snels IAK Beckerman H Lankhorst GJ | 2002 | Phys Rehabi Med2002，14，34： | 1 |
| 12 | The use of chlorophyll fluorescence nomenclature in plant stress physiology显示文摘 | Kooten 0 V Snel J F H | 1990 | Photosynthesis Research1990，，25： | 1 |
| 13 | Biomo lecular interactions measured by atomic force microscopy显示文摘 | Willemsen O H Snel M M Cambi A | 2000 | BiophysicalJournal2000，79，6： | 1 |
| 14 | ConserVation of gene order: a fingerprint of proteins that physically interact显示文摘 | Dandekar Thomas Berend Snel Martijn Huynen and Peer Bork | 1998 | Trends in Biochemical Sciences1998，23，： | 1 |
| 15 | The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract显示文摘 | Schell M A Karmirantzou M Snel B | 2002 | PNAS2002，99，14： | 1 |
| 16 | The use of chlorophyII fluorescence nomenclature in plant stress physiology 显示文摘 | VAN KOOTEN O SNEL J F H | 1990 | Photosynthesis Research1990，25，3： | 1 |
| 17 | The use of chlorophyll fluorescence nomenclature in plant stress physiology显示文摘 | Van Kooteu O Snel J F H | 1990 | Photosyn RES1990，25，： | 1 |
| 18 | The use of chlorophyll fluorescence nomenclature in plant stress physiology显示文摘 | KOOTEN O SNEL J E H | 1990 | Photosynthesis Research1990，25，3： | 1 |
| 19 | Compara- tive assessment of large-scale data sets of protein-protein interactions 显示文摘 | VON MERING C KRAUSE R SNEL B | 2002 | Nature2002，417，6887： | 1 |
| 20 | The use of chlorophyll fluorescence nomen- clature in plant stress physiology 显示文摘 | Kooten O Snel J F | 1990 | Photosynthesis Research1990，25，3： | 1 |
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