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| 1 | Frictional behaviors of rough soft contact on wet and dry pipeline surfaces:With application to deepwater pipelaying显示文摘Elastic rubbers are widely used in nature and engineering.In order to better understand soft rough contact under dry and wet conditions during deepwater pipelaying process,various polyurethane(PU)discs both in PU-pipe and PU-steel sliding combinations have been investigated by using self-developed tribometer.The tribological test results show that the friction coefficient can be clearly seen:PU90 | TAN GuiBin WANG DeGuo LIU ShuHai WANG Hao ZHANG SiWei | 2013 | Science China(Technological Sciences)2013，56，12： | 4 |
| 2 | Berberine alleviates non-alcoholic hepatic steatosis partially by promoting SIRT1 deacetylation of CPT1A in mice显示文摘Background:Berberine effectively alleviates non-alcoholic fatty liver disease(NAFLD).Nevertheless,the mechanism is incompletely comprehended.It has been reported that SIRT1 mediates lipid metabolism in liver and berberine promotes the expression of SIRT1 in hepatocytes.We hypothesized that SIRT1 mediated the effect of berberine on NAFLD.Methods:The effects of berberine on NAFLD were evaluated in C57BL/6J mice fed a high-fat diet(HFD)and in mouse primary hepatocytes and cell lines exposed to palmitate.The change of fatty acid oxidation(FAO)and the activity of CPT1A were observed in HepG2 cells.Quantitative real-time polymerase chain reaction and Western blot were employed to observe the expression of SIRT1 and lipid metabolism-related molecules.The interaction between SIRT1 and CPT1A was investigated by using co-immunoprecipitation assay in HEK293T cells.Results:Berberine treatment attenuated hepatic steatosis,reduced triglyceride(190.1611.2 lmol/g liver vs 113.667.6 lmol/g liver,P<0.001)and cholesterol(11.362.5 lmol/g liver vs 6.360.4 lmol/g liver,P<0.001)concentration in the liver,and improved lipid and glucose metabolism disorders compared with the HFD group.The expression of SIRT1 was reduced in the liver of NAFLD patients and mouse models.Berberine increased the expression of SIRT1 and promoted the protein level of CPT1A and its activity in HepG2 cells.SIRT1 overexpression mimicked the effect of berberine on reducing triglyceride levels in HepG2 cells,whereas SIRT1 knock-down attenuated the effect of berberine.Mechanistically,berberine increased the expression of SIRT1.SIRT1 deacetylated CPT1A at the Lys675 site,which suppressed its ubiquitin-dependent degradation,thereby promoting FAO and alleviating non-alcoholic liver steatosis.Conclusions:Berberine promoted SIRT1 deacetylation of CPT1A at the Lys675 site,which reduced the ubiquitin-dependent degradation of CPT1A and ameliorated non-alcoholic liver steatosis. | Peng Wang Ruikai Li Yuqi Li Siwei Tan Jie Jiang Huiling Liu Xiuqing Wei | 2023 | Gastroenterology Report2023，11，1： | 0 |
| 3 | Circumventing chemo-mechanical failure of Sn foil battery anode by grain refinement and elaborate porosity design显示文摘Tin (Sn) metal foil is a promising anode for next-generation high-energy–density lithium-ion batteries (LIBs) due to its high capacity and easy processibility. However, the pristine Sn foil anode suffers nonuniform alloying/dealloying reaction with lithium (Li) and huge volume variation, leading to electrode pulverization and inferior electrochemical performance. Herein, we proposed that reduced grain size and elaborate porosity design of Sn foil can circumvent the nonuniform alloy reaction and buffer the volume change during the lithiation/delithiation cycling. Experimentally, we designed a three-dimensional interconnected porous Sn (3DIP-Sn) foil by a facile chemical alloying/dealloying approach, which showed improved electrochemical performance. The enhanced structure stability of the as-fabricated 3DIP-Sn foil was verified by chemo-mechanical simulations and experimental investigation. As expected, the 3DIP-Sn foil anode revealed a long cycle lifespan of 4400 h at 0.5 mA cm^(−2) and 1 mAh cm^(−2) in Sn||Li half cells. A 3DIP-Sn||LiFePO_(4) full cell with LiFePO_(4) loading of 7.1 mg cm^(−2) exhibited stable cycling for 500 cycles with 80% capacity retention at 70 mA g^(−1). Pairing with high-loading commercial LiNi0.6Co0.2Mn0.2O_(2) (NCM622, 18.4 mg cm^(−2)) cathode, a 3DIP-Sn||NCM622 full cell delivered a high reversible capacity of 3.2 mAh cm^(−2). These results demonstrated the important role of regulating the uniform alloying/dealloying reaction and circumventing the localized strain/stress in improving the electrochemical performance of Sn foil anodes for advanced LIBs. | Shuibin Tu Xin Ai Xiancheng Wang Siwei Gui Zhao Cai Renming Zhan Yuchen Tan Weiwei Liu Hui Yang Chenhui Li Yongming Sun | 2021 | Journal of Energy Chemistry2021，30，11： | 0 |
| 4 | Stress-Regulation Design of Lithium Alloy Electrode toward Stable Battery Cycling显示文摘Metallic tin(Sn)foil is a promising candidate anode for lithium-ion batteries(LIBs)due to its metallurgical processability and high capacity.However,it suffers low initial Coulombic efficiency and inferior cycling stability due to its uneven alloying/dealloying reactions,large volume change and stress,and fast electrode structural degradation.Herein,we report an undulating LiSn electrode fabricated by a scalable two-step procedure involving mechanical lithography and chemical prelithiation of Sn foil.With the combination of experimental measurements and chemo-mechanical simulations,it was revealed the obtained undulating LiSn/Sn electrode could ensure better mechanical stability due to the pre-swelling state from Sn to Li x Sn and undulating structure of lithography in comparison with plane Sn,homogenize the electrochemical alloying/dealloying reactions due to the activated surface materials,and compensate Li loss during cycling due to the introduction of excess Li from Li_(x)Sn,thus enabling enhanced electrochemical performance.Symmetric cells consisting of undulating LiSn/Sn electrode with an active thickness of∼5 um displayed stable cycling over 1000 h at 1 mA cm^(-2) and 1 mAh cm^(-2) with a low average overpotential of<15 mV.When paired with commercial LiNi_(0.6)Co_(0.2)Mn_(0.2)O_(2)(NCM622)cathode with high mass loading of 15.8 mg cm^(-2),the full cell demonstrated a high capacity of 2.4 mAh cm^(-2) and outstanding cycling stability with 84.9% capacity retention at 0.5 C after 100 cycles.This work presents an advanced LiSn electrode with stress-regulation design toward high-performance LIBs,and sheds light on the rational electrode design and processing of other high-capacity lithium alloy anodes. | Chunhao Li Shuibin Tu Xin Ai Siwei Gui Zihe Chen Wenyu Wang Xiaoxiao Liu Yuchen Tan Hui Yang Yongming Sun | 2023 | Energy & Environmental Materials2023，6，1： | 0 |
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