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| 1 | Attention deficit hyperactivity disorder and gastrointestinal morbidity in a large cohort of young adults显示文摘BACKGROUND Although the association of attention deficit hyperactivity disorder(ADHD)with psychiatric disorders is well known,its association with somatic diseases is unclear.Only few studies have investigated the gastrointestinal(GI)morbidity in adult patients with ADHD.AIM To measure gastrointestinal comorbidity and its burden on healthcare in young adults with ADHD.METHODS The cohort included subjects aged 17-35 years recruited to the Israel Defense Forces in 2007-2013,33380 with ADHD and 355652 without(controls).The groups were compared for functional and inflammatory conditions of the gastrointestinal tract and clinic and specialist visits for gastrointestinal symptoms/disease during service(to 2016).Findings were analyzed by generalized linear models adjusted for background variables.RESULTS Compared to controls,the ADHD group had more diagnoses of functional gastrointestinal disorders(referred to as FGID),namely,dyspepsia[odds ratio(OR):1.48,95%confidence interval(CI):1.40-1.57,P<0.001],chronic constipation(OR:1.64,95%CI:1.48-1.81,P<0.001),and irritable bowel syndrome(OR:1.67,95%CI:1.56-1.80,P<0.001)but not of organic disorders(inflammatory bowel disease,celiac disease).They had more frequent primary care visits for gastrointestinal symptoms[rate ratio(RR):1.25,95%CI:1.24-1.26,P<0.001]and referrals to gastrointestinal specialists(RR:1.96,95%CI:1.88-2.03,P<0.001)and more episodes of recurrent gastrointestinal symptoms(RR:1.29,95%CI:1.21-1.38,P<0.001).Methylphenidate use increased the risk of dyspepsia(OR:1.49,95%CI:1.28-1.73,P<0.001)and constipation(OR:1.42,95%CI:1.09-1.84,P=0.009).CONCLUSION ADHD in young adults is associated with an excess of FGID and increased use of related health services.Research is needed to determine if an integrative approach treating both conditions will benefit these patients and cut costs. | Sivan Kedem Shlomit Yust-Katz Dan Carter Zohar Levi Ron Kedem Adi Dickstein Salah Daher Lior H Katz | 2020 | World Journal of Gastroenterology2020，26，42： | 2 |
| 2 | Adiponectin and human pregnancy 显示文摘 | Mazaki T S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，： | 1 |
| 3 | Adiponectin and human pregnancy显示文摘 | Mazaki T S Kanety H Sivan E | 2005 | Curt Diab Rep2005，5，4： | 1 |
| 4 | Adiponectin and human pregnancy 显示文摘 | Mazaki-Tovi S Kanety H Sivan E | 2005 | J Curr Diab Rep2005，5，： | 1 |
| 5 | Adiponectin and human pregnancy显示文摘 | Mazaki -Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，4： | 1 |
| 6 | Adiponectin, and human preg- nancy显示文摘 | Mazaki - Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，4： | 1 |
| 7 | The maximally achievable accuracy of linear optimal regulators and linear optimal filters显示文摘 | KWAKERNAAK H SIVAN R | 1972 | IEEE Trans Autom Control1972，17，1： | 1 |
| 8 | Adiponectin and human pregnancy显示文摘 | Mazaki-Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，4： | 1 |
| 9 | Establish- mentand characterization of new cellular lymphomamodel ex- pressing transgenic human MDRI显示文摘 | Findling-Kagan S Sivan H Ostrovsky O | 2005 | Leuk Res2005，9，4： | 1 |
| 10 | Adiponectin and human pregnancy显示文摘 | Maza ki-Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，4： | 1 |
| 11 | Adiponectin and human pregnancy 显示文摘 | Mazaki Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，4： | 1 |
| 12 | Establishment and characterization of new cellular lymphomamodel expressing transgenie human MDR1 显示文摘 | Findling-Kagan S Sivan H Ostrovsky O | 2005 | Leuk Res2005，29，4： | 1 |
| 13 | Adiponectin and human preg- nancy 显示文摘 | Mazaki-Tovi S Kanety H Sivan E | 2009 | J Curt Diab Rep2009，5，5： | 1 |
| 14 | Adiponectin and Human Pregnancy显示文摘 | Mazaki Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，4： | 1 |
| 15 | The Maximally Achievable Accuracy of Linear Optimal Regulators and Linear Optimal Filters 显示文摘 | Kwakemaak H Sivan R | 1972 | IEEE Transactions on Automatic Control (S0018-9286)1972，17，1： | 1 |
| 16 | Adiponectin and human pregnancy显示文摘 | Mazaki-Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，： | 1 |
| 17 | A self-aligned elevated source/drain MOSFET显示文摘 | PFIESTER J R SIVAN R D LIAW H M | 1990 | IEEE ElectronDevice Letters1990，11，9： | 1 |
| 18 | Establishment and characterization of new cellular lymphoma model expressing transgenic human MDRI显示文摘 | Findling-Kagan S Sivan H Ostrovsky O | 2005 | Leuk Res2005，29，4： | 1 |
| 19 | Adiponectin and human pregnancy 显示文摘 | Mazaki-Tovi S Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，4： | 1 |
| 20 | Adiponectin and human pregnancy 显示文摘 | Mazaki TS Kanety H Sivan E | 2005 | Curr Diab Rep2005，5，： | 1 |
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