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| 1 | Contemporary approach to diagnosis and classification of renal cell carcinoma with mixed histologic features显示文摘Renal cell carcinoma (RCC) is an important contributor to cancer-specific mortality worldwide. Targeted agents that inhibit key subtype-specific signaling pathways have improved survival times and have recently become part of the standard of care for this disease. Accurately diagnosing and classifying RCC on the basis of tumor histology is thus critical. RCC has been traditionally divided into clear-cell and non-clearcell categories, with papillary RCC forming the most common subtype of non-clear-cell RCC. Renal neoplasms with overlapping histologies, such as tumors with mixed clear-cell and papillary features and hybrid renal oncocytic tumors, are increasingly seen in contemporary practice and present a diagnostic challenge with important therapeutic implications. In this review, we discuss the histologic, immunohistochemical, cytogenetic, and clinicopathologic aspects of these differential diagnoses and illustrate how the classification of RCC has evolved to integrate both the tumor's microscopic appearance and its molecular fingerprint. | Kanishka Sircar Priya Rao Eric Jonasch Federico A. Monzon Pheroze Tamboli | 2013 | Chinese Journal of Cancer2013，32，6： | 4 |
| 2 | Nanoporous membrane device for ultra high heat flux thermal management显示文摘High power density electronics are severely limited by current thermal management solutions which are unable to dissipate the necessary heat flux while maintaining safe junction temperatures for reliable operation.We designed,fabricated,and experimentally characterized a microfluidic device for ultra-high heat flux dissipation using evaporation from a nanoporous silicon membrane.With~100 nm diameter pores,the membrane can generate high capillary pressure even with low surface tension fluids such as pentane and R245fa.The suspended ultra-thin membrane structure facilitates efficient liquid transport with minimal viscous pressure losses.We fabricated the membrane in silicon using interference lithography and reactive ion etching and then bonded it to a high permeability silicon microchannel array to create a biporous wick which achieves high capillary pressure with enhanced permeability.The back side consisted of a thin film platinum heater and resistive temperature sensors to emulate the heat dissipation in transistors and measure the temperature,respectively.We experimentally characterized the devices in pure vaporambient conditions in an environmental chamber.Accordingly,we demonstrated heat fluxes of 665±74 W/cm^(2) using pentane over an area of 0.172mm×10mm with a temperature rise of 28.5±1.8 K from the heated substrate to ambient vapor.This heat flux,which is normalized by the evaporation area,is the highest reported to date in the pure evaporation regime,that is,without nucleate boiling.The experimental results are in good agreement with a high fidelity model which captures heat conduction in the suspended membrane structure as well as non-equilibrium and sub-continuum effects at the liquid–vapor interface.This work suggests that evaporative membrane-based approaches can be promising towards realizing an efficient,high flux thermal management strategy over large areas for high-performance electronics. | Daniel F.Hanks Zhengmao Lu Jay Sircar Todd R.Salamon Dion S.Antao Kevin R.Bagnall Banafsheh Barabadi Evelyn N.Wang | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 3 | Application of machine learning and artificial intelligence in oil and gas industry显示文摘Oil and gas industries are facing several challenges and issues in data processing and handling.Large amount of data bank is generated with various techniques and processes.The proper technical analysis of this database is to be carried out to improve performance of oil and gas industries.This paper provides a comprehensive state-of-art review in the field of machine learning and artificial intelligence to solve oil and gas industry problems.It also narrates the various types of machine learning and artificial intelligence techniques which can be used for data processing and interpretation in different sectors of upstream oil and gas industries.The achievements and developments promise the benefits of machine learning and artificial intelligence techniques towards large data storage capabilities and high efficiency of numerical calculations.In this paper a summary of various researchers work on machine learning and artificial intelligence applications and limitations is showcased for upstream and sectors of oil and gas industry.The existence of this extensive intelligent system could really eliminate the risk factor and cost of maintenance.The development and progress using this emerging technologies have become smart and makes the judgement procedure easy and straightforward.The study is useful to access intelligence of different machine learning methods to declare its application for distinct task in oil and gas sector. | Anirbid Sircar Kriti Yadav Kamakshi Rayavarapu Namrata Bist Hemangi Oza | 2021 | Petroleum Research2021，6，4： | 3 |
| 4 | Gibberellins from mangrove plants 显示文摘 | Ganguly S N Sircar S M | 1974 | Phytochemistry1974，13，： | 2 |
| 5 | Development of interstitial cells of Cajal in a full-term infant without an enteric nervous system显示文摘 | Huizingu J D Berezin I Sircar K | 2001 | Gastroenterology2001，120，2： | 2 |
| 6 | Applications of silica and titanium dioxide nanoparticles in enhanced oil recovery:Promises and challenges显示文摘The Surface engineering of nanoparticles has contributed to the development of nanoscience and nanotechnology by designing of new material depends on their surface modifier with series of functional properties and applications.The dispersed nanoparticles can change or modify the interfacial properties in liquid-liquid system in aqueous phase if their surface is modified by ionic surfactant.The interfacial energy in nanoparticles-brine system,the ions tends to modify the transport phenomena in pore channels and improve the recovery.The use of the suspension of the particles at nanoscales can offer some advantages of induced sedimentation stability by surface force easily counter balance the force of gravity.This happened due to their nanosize,nanostructure,high volume to surface ratio and strong rock fluid interaction.It also influences the emulsion stability and alters the surface characteristics of surfactant and polymer within the rock in porous medium.Some of the problems associated with conventional EOR processes have been solved by nanoscience applications due to their potential response to reduce the interfacial tension at low to ultra-low level,wettability reversal and improvement in rheology of formation fluids.The large specific surface area,high reactivity,toughness and other properties of Nanoparticles can immensely improve the oil mobility compare to conventional EOR.This paper updates the latest review,experimental evidences and re-interpretation of past research data and applications in respect of silica and titanium dioxide nanoparticles in different environment within surfactant(s),polymer(s),polymer-surfactant EOR processes.The nanotechnology therefore is an effective and alternate solution to brush up the traditional EOR approach with state of art technology which can revolutionize the total oil and gas industry and can contributes significantly to enhance the economics of oil field industry. | G.S.Negi Sircar Anirbid P.Sivakumar | 2021 | Petroleum Research2021，6，3： | 2 |
| 7 | Plasma Pulse Technology: An uprising EOR technique显示文摘Conventionally oil recovery factor is too low,which leaves great prospects for the application of enhanced oil recovery(EOR)methods to increase recovery factor.EOR methods are capital intensive and few are environmentally hazardous.So the paper discusses on the alternate enhanced oil recovery technique which has tremendous potential to curb the challenges of conventional EOR methods.Plasma pulse technology(PPT)aided EOR treatment is administered with an electric wireline conveyed plasma pulse generator tool that is run in the well and positioned alongside the perforations.Using energy stored in the generator's capacitors,a plasma arc is created that emits a tremendous amount of heat and pressure for a fraction of a second.This in turn creates a broad band of hydraulic impulse acoustic waves that are powerful enough to clean perforations and near wellbore damage.These waves continue to resonate deep into the reservoir,exciting the fluid molecules and increasing the reservoirs natural resonance to the degree that it can break larger hydrocarbon molecules to smaller one and simultaneously reducing adhesion tension which results in increased mobility of hydrocarbons.The plasma pulse technology has been successfully used on production as well as injection wells.It has been used often as a remedial procedure to increase well's productivity that has been on production for a period of time.This paper throws light on fundamentals of this advancing plasma pulse technology,contrasting it with recent EOR techniques.Effectiveness of treatment in increasing oil recovery,it's applicability to different reservoir types and results achieved so far are also covered in the paper. | Karan Patel Manan Shah Anirbid Sircar | 2018 | Petroleum Research2018，3，2： | 2 |
| 8 | A comprehensive review of the application of nano-silica in oil well cementing显示文摘Oil and Gas Industry is a Multi-Billion Dollar Industry.Drilling a well is costly,right from exploration to drilling and production to Enhanced Oil Recovery(EOR).Nanotechnology has the potential to introduce revolutionary changes in several areas of the oil and gas industry,such as exploration,drilling,cementation,production,EOR,etc.Use of Nanotechnology in the cement slurry can also achieve solutions to some of the problems pertaining to oil well cementation.Nano-silica is a better alternative compared to conventional additives like calcium chloride and silica,because as compared to calcium chloride and silica,the amount of nano-silica to be added is very small.Nano-silica acts as a multi-functional additive.Upon addition of nano-silica to cement slurry,there is a decrease in the thickening time,an increase in the compressive strength,decrease in porosity and permeability within the cement and also a decrease in the fluid loss.Incorporation of nano-silica ensures proper cementation and greater integrity of the well.Nano-silica helps in decreasing the wait on cement(WOC)time and therefore reduces the overall capital cost.Nano-silica is highly recommended for deep offshore wells where high temperature and high pressure are often encountered.This paper discusses the behavior of Nano-silica at high temperatures and also reviews effects of Nano-silica on various properties of cement. | Akshar Thakkar Aakash Raval Shishir Chandra Manan Shah Anirbid Sircar | 2020 | Petroleum2020，6，2： | 2 |
| 9 | 活性炭:气体分离和贮存显示文摘活性炭的孔结构及表面化学性质的范围很大。在设计实际可行的变压吸附与变温吸附过程中,活性炭可被用来分离和纯化混合气体。因为活性炭对气体的吸附强度相对缓和,从而使脱附较容易,故在气体分离过程中,作为吸附剂的活性炭往往比沸石优越。本文综合介绍了活性炭的三种工业用途,(a)从被污染气体中除去痕量杂质,(b)从蒸气—甲烷重整尾气中制H2,(c)从空气中制N2。同时,还描述了活性炭用于气体分离和纯化的四种新用途,它们包括(a)通过大分子烃在由聚合物基体炭化生成之纳米孔炭膜上的选择性表面流动而分离烃和H2的混合物;(b)憎水性炭经表面氧化生成对水选择性吸附的微孔炭质吸附剂,通过变压吸附进行气体干燥;(c)通过炭质吸附剂—催化剂复合体系选择性吸附和在位氧化而除去空气中痕量易挥发性有机物;(d)用高表面积炭储存压缩的天然气。 | SircarS GoldenTC RaoMB 吴明铂 | 1997 | 新型炭材料1997，12，2： | 2 |
| 10 | Morbidity and mortality among patients with hip fracture surgically repaired within and af- ter 4- hours显示文摘 | Sircar P Godkar D Mahgerefteh S | 2007 | Am J Ther2007，14，6： | 1 |
| 11 | Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors显示文摘 | Sircar K Hewlett BR Huizinga JD | 1999 | Am J Surg Pathol1999，23，4： | 1 |
| 12 | Sorption-enhanced reaction process for hydrogen production显示文摘 | Hufton J Mayorga S Sircar S | 1999 | AIChE J1999，45，： | 1 |
| 13 | Interstitial cells of Cajal as precursors for gastrointestinal stromal tumors显示文摘 | Sircar K Hewlett BR Huizinga JD | 1999 | Am J Surg Pathol1999，23，： | 1 |
| 14 | Interstitial cells of Cajal as precursors for gastrointestinal stromal tumors 显示文摘 | Sircar K Hewlett BR Huizinga JD | 1999 | Am J Surg Pathol1999，23，： | 1 |
| 15 | Laser-clad Ni70Al20Cr7Hf3 alloys with extended solid solution of Hf:Part Ⅰ显示文摘 | Sircar S Ribaudo C Mazumder J | 1989 | Microstrcture Evolution Metall Trans A1989，20，11： | 1 |
| 16 | Laser cladding of zirconium on magnesium for improved corrosion properties显示文摘 | R. Subramanian S. Sircar J. Mazumder | 1991 | Journal of Materials Science1991，，4： | 1 |
| 17 | Plasmacytoid urothelial carcinoma, a chemosensitive cancer with poor prognosis, and peritoneal carcinomatosis 显示文摘 | DAYYANI F CZERNIAK BA SIRCAR K | 2013 | J Urol2013，189，5： | 1 |
| 18 | T cell targeting of TAG72 +tumor cells by a chimeric receptor with antibody-like specificity for a carbohydrateepitope 显示文摘 | heuser C Sircar R at al | 1997 | Gastroenterology1997，113，4： | 1 |
| 19 | Renal pelvis squamous cell carcinoma and renal cell carcinoma in a tuberculous kidney显示文摘 | A1-Assiri M Al-Otaibi M F Sircar K | 2004 | Scientific World Journal2004，4，： | 1 |
| 20 | Prioritizing genes associated with prostate cancer development显示文摘 | Gorlov IP Sircar K Zhao H | | 0，，： | 1 |
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