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133篇 您的检索式：作者名="Sinibaldi"

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	题名	作者	年代	出处	被引量
1	Nerve growth factor involvement in liver cirrhosis and hepatocellular carcinoma显示文摘AIM: To define NGF (nerve growth factor) and its high- affinity receptor trkANGF presence and distribution in fibrotic liver and in HCC, and to verify if NGF might have a role in fibrosis and HCC. METHODS: Intracellular distribution of NGF and trkANGF were assessed by immunohistochemistry and immuno- electron microscopy in liver specimens from HCC, cirrhosis or both. ELISA was used to measure circulating NGF levels. RESULTS: NGF and trkANGF were highly expressed in HCC tissue, mainly localized in hepatocytes, endothelial and some Kupffer cells. In the cirrhotic part of the liver they were also markedly expressed in bile ducts epithelial and spindle-shaped cells. Surprisingly, in cirrhotic tissue from patients without HCC, both NGF and trkANGF were negative. NGF serum levels in cirrhotic and/or HCC patient were up to 25-fold higher than in controls. CONCLUSION: NGF was only detected in liver tissue with HCC present. Intracellular distribution suggests paracrine and autocrine mechanisms of action. Better definition of mechanisms may allow for therapeutic and diagnostic/prognostic use of NGF.	Guido Rasi Annalucia Serafino Lia Bellis Maria Teresa Lonardo Federica Andreola Manuela Zonfrillo Giovanni Vennarecci Pasquale Pierimarchi Paola Sinibaldi Vallebona Giuseppe Maria Ettorre Eugenio Santoro Claudio Puoti	2007	World Journal of Gastroenterology2007，13，37：	13
2	Combination therapy in the treatment of chronic viral hepatatitis and prevention of hepatocellular carcinoma 显示文摘	Rasi G Pierimarchi P Sinibaldi Vallebona P	2003	Int Immunopharmacol2003，3，8：	1
3	Anti-tumor effect of combined treatment with thymosin alpha 1 and interlerkin-2 after 5-fluofouracil in liver metastases from colorectal cancer in rats 显示文摘	Silecchia G Sinibaldi VP	1994	Int J Cancer1994，57，5：	1
4	Stat3 - mediated Myc expression is required for Src transformation and PDGFinduced mitogenesis显示文摘	Bowman T Broome MA Sinibaldi D	2001	Proc Natl Acad Sci USA2001，98，13：	1
5	Marimastat in the treatment of patients with biochemically relapsed prostate cancer: a prospective randomized, double-blind, phase I/II Trial 显示文摘	Rosenbaum E Sinibaldi V Carducci MA	2005	Clin Cancer Res2005，11，：	1
6	Additive effects of genetic variation in dopamine regulating genes on working memory cortical activity in human brain显示文摘	Bertolino A Blasi G Latorre V Rubino V Rampino A Sinibaldi L		0，，15：	1
7	Stat3-mediated Mye expression is required for Src transformation and PDGFinduced mitogenesis 显示文摘	Bowman T Broome M A Sinibaldi D	2001	Proc Natl Acad Sci USA2001，98，13：	1
8	Pachydermoperiostosis:an update显示文摘	Castori M Sinibaldi L Mingarelli R	2005	Clin Genel2005，68，6：	1
9	Epistasis between dopamine regulating genes identifies a nonlinear response of the human hippocampus during memory tasks显示文摘	Bertolino A Di Giorgio A Blasi G Sambataro F. Caforio G. Sinibaldi L.		0，，03：	1
10	Transient plasma ignition of quiescent and flowing air/ fuel mixtures显示文摘	Wang F Liu J B Sinibaldi J	2005	IEEE Transactions on Plasma Science2005，33，2：	1
11	Incidence of EMS-treated out-of-hospital cardiac arrest in the United States显示文摘	Rea TD Eisenberg MS Sinibaldi G	2004	Resuscitation2004，63，1：	1
12	Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome C as proapoptotic protein显示文摘	Caroppi P Sinibaldi F Fiorucci L	2009	Curr Med Chem2009，16，31：	1
13	Mutations of the Nogo-66 receptor (RTN4R) gene in schizophrenia显示文摘	Sinibaldi L De Luca A Bellacchio E	2004	Hum Mutat2004，24，：	1
14	Apoptosis and human diseases : mitoehondrion damage and lethal role of released cyto- chrome C as proapoptotic protein显示文摘	Caroppi P Sinibaldi F Fiorucci L	2009	Curr Med Chem2009，16，31：	1
15	Induction of p21WAF1 /CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblast:role of activated Stat3 signaling显示文摘	Sinibaldi D Wharton W Turkson J	2000	Onco-gene2000，19，48：	1
16	Mesoporous M41S materials in capillary gas chromatography显示文摘	Raimondo M Perez G Sinibaldi N	1997	Chem Commun1997，，15：	1
17	Combination therapy in the treatment of chronic viral hepatitis and prevention of hepatocellular carcinoma 显示文摘	Rasi G Pierimarchi P Sinibaldi Vallebona P	2003	Int Immunopharmacol2003，3，8：	1
18	Combination therapy in the treatment of chronic viral hepatitis and prevention of hepatocellular carcinoma显示文摘	Rasi G Pierimarchi P Sinibaldi Vallebona P	2003	Int Immunopharmacol2003，3，8：	1
19	Incidence of EMS-trea-ted out - of - hospital cardiac in the United States显示文摘	Rea TD Eisenberg MS Sinibaldi G	2004	Resuscita tion2004，63，：	1
20	COMT Val 158 Met polymorphism predicts negative symptoms response to treatment with olanzapine in schizophrenia显示文摘	Alessandro Bertolino Grazia Caforio Giuseppe Blasi Antonio Rampino Lorenzo Sinibaldi Sophia Douzgou Marcello Nardini Daniel R. Weinberger Bruno Dallapiccola	2007	Schizophrenia Research2007，，1：	1

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