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11篇 您的检索式:作者名="Simone Fulda"
    题名 作者 年代 出处 被引量
1The Role of Cyclooxygenase-2 in Cell Proliferation and Cell Death in Human Malignancies显示文摘Cyril Sobolewski Claudia Cerella Mario Dicato Lina Ghibelli Marc Diederich Simone Fulda 2010International Journal of Cell Biology2010,,:2
2Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy显示文摘 Simone Fulda Claudia Friesen 2001Blood2001,98,:1
3Apoptosis in hematological disorders显示文摘Klaus-Michael Debatin Karsten Stahnke Simone Fulda 2003Seminars in Cancer Biology2003,,2:1
4Metabolic Inhibitors Sensitize for CD95 (APO-1/Fas) -induced Apoptosis by Down-Regulating Fas-associated Death Domain-like Interleukin 1-Converting Enzyme Inhibitory Protein Expression 显示文摘 Eric Meyer Klaus-Michael Debatin 2000Cancer Res2000,60,:1
5Metabolic Inhibitors Sensitize for CD95 (APO-1 /Fas)-induced Apoptosis by Down-Regulating Fas-associated Death Domain-like Interleukin 1-Converting Enzyme Inhibitory Protein Expression 显示文摘 Eric Meyer Klaus-Michael Debatin 2000Cancer Res2000,60,:1
6Selected Secondary Plant Metabolites for Cancer Therapy显示文摘Secondary plant metabolites reveal numerous biological activities making them attractive as resource for drug development of human diseases.As the majority of cancer drugs clinically established during the past half century is derived from nature, cancer researchers worldwide try to identify novel natural products as lead compounds for cancer therapy. Natural products are considered as promising cancer therapeutics,either as single agents or in combination protocols, to enhance the antitumor activity of additional therapeutic modalities. Most natural compounds exert pleotrophic effects and modulate various signal transduction pathways. A better understanding of the complex mechanisms of action of natural products is expected to open new perspectives in coming years for their use alone or in combination therapies in oncology.Two major strategies to identify novel drug candidates from nature are the bioactivity-guided fractionation of medicinal plant extracts to isolate cytotoxic chemicals and the identification of small molecules inhibiting specific targets in cancer cells. In the present review, we report on our own efforts to unravel the molecular modes of action of phytochemicals in cancer cells and focus on resveratrol, betulinic acid,artesunate, dicentrine and camptothecin derivatives.Simone Fulda Thomas Efferth 2015World Journal of Traditional Chinese Medicine2015,1,1:1
7Modulation of Apoptosis by Natural Products for Cancer Therapy显示文摘Simone Fulda 2010Planta Med2010,,11:1
8TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL - induced apoptosis mediated by NF- KB显示文摘Harald Ehrhardt Simone Fulda 2003Oncogene2003,22,:1
9Smac mimetic and oleanolic acid synergize to induce cell death in human hepatocellular carcinoma cells显示文摘Juliane Liese Behnaz Ahangarian Abhari Simone Fulda 2015Cancer Letters2015,365,1:1
10The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells显示文摘Eva Rettinger Selim Ku?I Ivonne Naumann Petra Becker Hermann Kreyenberg Martina Anzaghe Andre Willasch Ulrike Koehl Gesine Bug Martin Ruthardt Thomas Klingebiel Simone Fulda Peter Bader 2012Cytotherapy2012,,:1
11Act ivation of Akt predicts poor outcome in neuroblastoma 显示文摘Opel D Poremba C Simon T Debar in K M Fulda S 2007Cancer Res2007,67,:1
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