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| 1 | Peritoneal carcinomatosis of colorectal origin:Incidence,prognosis and treatment options显示文摘Peritoneal carcinomatosis (PC) is one manifestation of metastatic colorectal cancer (CRC). Tumor growth on intestinal surfaces and associated fluid accumulation eventually result in bowel obstruction and incapacitating levels of ascites, which profoundly affect the quality of life for affected patients. PC appears resistant to traditional 5-fluorouracil-based chemotherapy, and surgery was formerly reserved for palliative purposes only. In the absence of effective treatment, the histori-cal prognosis for these patients was extremely poor, with an invariably fatal outcome. These poor outcomes likely explain why PC secondary to CRC has received little attention from oncologic researchers. Thus, data are lacking regarding incidence, clinical disease course, and accurate treatment evaluation for patients with PC. Recently, population-based studies have revealed that PC occurs relatively frequently among patients withCRC. Risk factors for developing PC have been identi-fied:right-sided tumor, advanced T-stage, advanced N-stage, poor differentiation grade, and younger age at diagnosis. During the past decade, both chemother-apeutical and surgical treatments have achieved prom-ising results in these patients. A chance for long-term survival or even cure may now be offered to selected patients by combining radical surgical resection with intraperitoneal instillation of heated chemotherapy. This combined procedure has become known as hy-perthermic intraperitoneal chemotherapy. This edito-rial outlines recent advancements in the medical and surgical treatment of PC and reviews the most recent information on incidence and prognosis of this disease. Given recent progress, treatment should now be considered in every patient presenting with PC. | Yvonne LB Klaver Valery EPP Lemmens Simon W Nienhuijs Misha DP Luyer Ignace HJT de Hingh | 2012 | World Journal of Gastroenterology2012，18，39： | 9 |
| 2 | Inhibitory effect of curcuminoids on MCF-7 cell proliferation and structure-activity relationships显示文摘 | Simon A Allais DP Duroux JL | 1998 | Cancer Letters1998，129，： | 1 |
| 3 | Inhibitory effect of curcuminoids on MCF-7 cell proliferation and structure-activity relationships显示文摘 | Simon A Allais DP Duroux JL | 1998 | Cancer Letters1998，129，1： | 1 |
| 4 | But watch out for the weather- factors affecting adherence to progressive resistance exercise for persons with COPD显示文摘 | Simone DO Nicholas FT Jennifer DP | 2007 | Journal of Cardiopulmonary Rehabilitation and Prevention2007，27，： | 1 |
| 5 | Randomized clinical trials:perspectives on some recent ideas显示文摘 | Simon RM Ffiedewald WT | 1976 | N Engl J Med1976，295，5： | 1 |
| 6 | Understanding cross-national differences in depression prevalence 显示文摘 | Simon GE Goldberg DP Von Korff M | 2002 | Psychol Med2002，32，4： | 1 |
| 7 | Symmetry-based resistance as a novel means of lower limb rehabilitation显示文摘 | Simon AM Brent Gillespie R Ferrls DP | 2007 | J Biomech2007，40，6： | 1 |
| 8 | Symmetry-based resistance as a novel means of lower limb rehabilitation 显示文摘 | Simon AM Brent Gillespie R Ferris DP | 2007 | JBiomech2007，40，6： | 1 |
| 9 | Inhibition effects of curcuminoids on MCF-7 cell proliferation and structure-activity relationships 显示文摘 | Simon A Allais DP Duroux JL | 1998 | Cancer Lett1998，129，： | 1 |
| 10 | A pilot study examining the role of zileuton in atopic dermatitis 显示文摘 | Woodmansee DP Simon RA | 1999 | Ann Allergy Asthma Immunol1999，83，6： | 1 |
| 11 | Randomized clinical trials: perspectives on some recent ideas 显示文摘 | Byar DP Simon RM Friedewald WT | 1976 | N Engl J Med1976，295，5： | 1 |
| 12 | Upregulated JAG1 enhances cell proliferation in adrenocortical carcinoma 显示文摘 | Simon DP Giordano TJ Hammer GD | 2012 | Clin Cancer Res2012，18，9： | 1 |
| 13 | Semen qualityand hormone levels among radiofrequency heater operators显示文摘 | EVENSON DP SIMON SD CONOVER DL | 2000 | J Occup Environ Med2000，42，： | 1 |
| 14 | Inhibitory effect of curcuminiods on MCF-7 cell proliferation and structure-activity rclatiohship显示文摘 | Simon A Aais DP Duroux JL | 1998 | Cancer Lctt1998，129，： | 1 |
| 15 | Massive surgical emphysema following transanal endoscopic microsurgery显示文摘We describe an impressive and rare case of surgical emphysema after minimally invasive rectal surgery. This case reports on a patient who developed mas-sive retroperitoneal, intraperitoneal and subcutaneous emphysema directly following a transanal endoscopic microsurgery(TEM) procedure for a rectal intramuco-sal carcinoma. Free intra-abdominal air after gastro-intestinal surgery can be a sign of a bowel perforation or anastomotic leakage. This is a serious complication often requiring immediate surgery. In our patient an abdominal computed tomography-scan with rectal con-trast showed no signs of a rectal perforation. Therefore this emphysema was caused by the insufflation of CO2 gas in the rectum during the TEM-procedure. Conserva-tive treatment resulted in an uneventful recovery. With the increasing usage of TEM for rectal lesions we ex-pect this complication to occur more often. After ruling out a full thickness rectal wall perforation in patients with surgical emphysema following TEM, conservative treatment is the treatment of choice. | Geert AAM Simkens Simon W Nienhuijs Misha DP Luyer Ignace HJT de Hingh | 2014 | World Journal of Gastrointestinal Surgery2014，6，8： | 1 |
| 16 | Inhibitory effect of eurcuminoids on MCF-7 cell proliferation and structure-activity relationships显示文摘 | Simon A Allais DP I)uroux JL | 1998 | Cancer Lett1998，129，： | 1 |
| 17 | The safety of autologous fat transfer in breast cancer:Lessons from stem cell biology显示文摘 | Robert AP Simon JL Marc DP | | 0，，： | 1 |
| 18 | Semen quality and hormone levels among radiofrequeney heater operators显示文摘 | Evenson DP Simon SD Conover DL | 2000 | J Occup Environ Med2000，42，： | 1 |
| 19 | Randomized clinical trials:perspectives on some recent ideas显示文摘 | Byar DP Simon RM Friedewald WT | 1976 | N Engl J Med1976，295，5： | 1 |
| 20 | Randomized clinical trials perspectives on some recent ideas显示文摘 | Byar DP Simon RM Friedewald WT | 1976 | N Engl J Med1976，295，5： | 1 |
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