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| 1 | Isolation of the mucilages from Hibiscus rosasinensis linn.and Okra(Abelmoschus esculentus linn.) and studies of the binding effects of the mucilages显示文摘Objective:To isolate and evaluate comparatively the binding efficacy of the mucilages obtained from the plants of Hibiscus rosasinensis and Okra(Abelmoschus esculentus).Methods:Extraction of mucilages from the leaves of Hibiscus and pods of Okra(Ladies finger) was carried out by a cold maceration process.The extracted mucilages were subjected to various physicochemical properties for its suitability as an excipient in the formulation of tablet dosage form.Different concentrations(10,8,5,2 and 1%w/v) of binder solutions of Hibiscus and Okra were used for the formulation of tablets and the formulated tablets were evaluated by studying the standard parameters like diameter,thickness,weight variation,hardness,friability,disintegration and in vitro dissolution.Stability studies of the formulated tablets were conducted for four weeks. Results:The formulated tablets prepared using the mucilages of both Hibiscus and Okra had good appearance.The in vitro drug release profile of the tablets prepared using Okra mucilage had an optimum of 90%at a mucilage concentration of 1%w/v concentration mucilage itself within 4 h.Conclusions:According to the observations,the lower concentration levels of Okra can be used as an alternative binder to starch.The higher concentration levels of Okra mucilage show a slow and sustained release,and can be considered as an alternative natural excipient in the modified drug delivery systems.At the same time,the above natural excipient of Hibiscus mucilage could be used as a platform for prolonged release if its binder concentrations are increased. | Ameena K Dilip C Saraswathi R Krishnan PN Sankar C Simi SP | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 8 |
| 2 | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery显示文摘 | C K Simi T Emilia Abraham | 2007 | Bioprocess and Biosystems Engi- neering2007，30，： | 1 |
| 3 | Multi-type childhood abuse, strategies of coping, and psychological adaptations in young adults 显示文摘 | SESAR K SIMIe N BARISIe M | 2010 | Croatian Med J2010，51，5： | 1 |
| 4 | Signless Laplaeians of finite graphs显示文摘 | Cvetkovie D Rowlinson P Simie S K | 2007 | Linear Algebra Appl2007，432，： | 1 |
| 5 | Clinical implementation of noninvasive prenatal testing among maternal fetal medicine specialists显示文摘 | Haymon L Simi E Moyer K | 2014 | Prenat Diagn2014，34，5： | 1 |
| 6 | Q -integral graphs with edge -degrees at most five显示文摘 | Simie S K Stanic Z | 2008 | Discrete Math2008，308，： | 1 |
| 7 | Potent protection of gallic acid against DNA oxidation: Results of human and animal experiments显示文摘 | Franziska Ferk Asima Chakraborty Walter J?ger Michael Kundi Julia Bichler Miroslav Mi?ík Karl-Heinz Wagner Bettina Grasl-Kraupp Sandra Sagmeister Gerald Haidinger Christine Hoelzl Armen Nersesyan Maria Du?inská Tatjana Simi? Siegfried Knasmüller | 2011 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2011，，1： | 1 |
| 8 | Clinical implementation of noninva- sive prenatal testing among maternal fetal medicine specialists 显示文摘 | Haymon L Simi E Moyer K | 2014 | Prenat Diagn2014，34，5： | 1 |
| 9 | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery 显示文摘 | SIMI C K EM1LIA T | 2007 | Bioprocess Biosyst Eng2007，30，3： | 1 |
| 10 | Top management team diversity,group process and strategic consensus显示文摘 | Knight D Pearce C I Smith K Golan J D Sims H P Simi J H K A Flood P | 1999 | Strategic Management Jamal1999，20，3： | 1 |
| 11 | Signless Laplacians of finite graphs显示文摘 | CVETKOVI D ROWLINSON P SIMI S K | 2007 | Linear Algebra Appl2007，432，： | 1 |
| 12 | Eigenvalue bounds for the signless Laplacian显示文摘 | CVETKOVI D ROWLINSON P SIMI S K | 2007 | Pub De L Math2007，81，95： | 1 |
| 13 | Q-integral graphs with edge-degrees at most five显示文摘 | SIMI S K STANIC Z | 2008 | Discrete Math2008，308，： | 1 |
| 14 | The chitinase encoding to based chiA gone endows Pseudarnonas fluorescens with the capacity to control plant pathogens in soil显示文摘 | Simi K | 1994 | Germ1994，147，： | 1 |
| 15 | Hydrophobic grafted and cross-linked starch nan oparticles for drug delivery 显示文摘 | Simi C K Abraham Emilia T | 2007 | Bioprocess Biosyst Eng2007，30，3： | 1 |
| 16 | Towards a spectral theory of graphs based on signless Laplacian, II显示文摘 | Cvetkovid D Simi~ S K | 2010 | Linear Algebra Appl2010，432，9： | 1 |
| 17 | Towards a spectral theory of graphs based on signless Laplacian, III显示文摘 | Cvetkovi6 D Simi~ S K | 2010 | Appl Anal Discrete Math2010，4，1： | 1 |
| 18 | Towards a spectral theory of graphs based on the signless Laplacian II 显示文摘 | CVETKOVI C D M SIMI C S K | 2010 | Linear Algebra Appl2010，432，9： | 1 |
| 19 | Cardiac injury in child managed successfully in underprivileged hospital of Africa显示文摘 | Gnassingbe K SimI awo K Egbohou P | 2013 | World Journal for Pediatric&Con- genital Heart Surgery2013，4，3： | 1 |
| 20 | The combined effects of croeslinking and high crystaUinity on the microstructural and mechanical properties of ultra high molecular weight polyethylene 显示文摘 | SIMIS K S BISTOLFI A BELLARE A | 2006 | Biomaterials2006，27，： | 1 |
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