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| 1 | Pilot-scale extraction and fractional separation of onion oleoresin using supercritical carbon dioxide显示文摘 | Simándi B Sass-Kiss Czukor B | 2000 | Journal of Food Engineering2000，46，3： | 1 |
| 2 | Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin显示文摘 | Simák J Holada K Vostal JG | | 0，，： | 1 |
| 3 | Neuroprotection in diabetic retinopathy显示文摘 | Hernández C Simó R | | 0，，： | 1 |
| 4 | Intravitreous anti-VEGF for diabetic retinopathy:hopes and fears for a new therapeutic strategy显示文摘 | Simó R Hernández C | 2008 | Diabetologia2008，51，： | 1 |
| 5 | Topical ocular administration of DPP-Ⅳ inhibitors:a new approach for treating diabetes-induced retinal neurodegeneration显示文摘Retinal neurodegeneration plays a significant role in the pathogenesis of diabetic retinopathy(DR),the leading cause of preventable blindness.In fact,the American Diabetes Association has defined DR as a highly specific neurovascular complication(Solomon et al.,2017).Therefore,it is no longer acceptable to consider DR as merely a microvascular complication.In this regard,the term diabetic retinal disease(DRD)has been proposed as a broader term comprising microangiopathy and neurodegeneration.However,there are currently no treatments available that directly target the neurodegenerative changes of DR.This paper will give new insights into the translational research in this field with particular emphasis on glucagon-like peptide 1/dipeptidyl peptidase IV(GLP-1/DPP-IV)inhibitors. | Rafael Simó Cristina Hernández | 2024 | Neural Regeneration Research2024，19，4： | 1 |
| 6 | 查看详情显示文摘 | L I Simándi T M Simándi Z May | | 0，，1： | 1 |
| 7 | Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls显示文摘 | Simón-Sánchez J Singleton AB | 2008 | Hum Mol Genet2008，17，13： | 1 |
| 8 | Inreavitreous anti-VEGF for diabetic retinopathy:hopes and fears for a new therapeuticstrategy显示文摘 | Simó R Hernández C | | 0，，09： | 1 |
| 9 | Neurodegeneration:An early event of diabetic retinopathy显示文摘Diabetic retinopathy(DR) has been classically considered to be a microcirculatory disease of the retina caused by the deleterious metabolic effects of hyperglycemia per se and the metabolic pathways triggered by hyperglycemia.However,retinal neurodegeneration is already present before any microcirculatory abnormalities can be detected in ophthalmoscopic examination.In other words,retinal neurodegeneration is an early event in the pathogenesis of DR which predates and participates in the microcirculatory abnormalities that occur in DR.Therefore,the study of the mechanisms that lead to neurodegeneration will be essential to identify new therapeutic targets in the early stages of DR.Elevated levels of glutamate and the overexpression of the renin-angiotensin-system play an essential role in the neurodegenerative process that occurs in diabetic retina.Among neuroprotective factors,pigment epithelial derived factor,somatostatin and erythropoietin seem to be the most relevant and these will be considered in this review.Nevertheless,it should be noted that the balance between neurotoxic and neuroprotective factors rather than levels of neurotoxic factors alone will determine the presence or absence of retinal neurodegeneration in the diabetic eye.New strategies,based on either the delivery of neuroprotective agents or the blockade of neurotoxic factors,are currently being tested in experimental models and in clinical pilot studies.Whether these novel therapies will eventually supplement or prevent the need for laser photocoagulation or vitrectomy awaits the results of additional clinical research. | Marta Villarroel Andreea Ciudin Cristina Hernández Rafael Simó | 2010 | World Journal of Diabetes2010，1，2： | 41 |
| 10 | Parkinson's disease due to the R1441G mutation in Dardarin:a founder effect in the Basques显示文摘 | Simón-Sánchez J Martí-Massó JF Sánchez-Mut JV | 2006 | Mov Disord2006，21，11： | 1 |
| 11 | The role of direct high-resolution mass spectrometry in foodomics显示文摘 | IBá?EZ C SIMó C GARCíA-CA?AS V | 2015 | Analytical and Bioanalytical Chemistry2015，407，21： | 1 |
| 12 | Importance of phenolic compounds for the characterization of fruit juices显示文摘 | Brí gida Fern á ndez de Simó n Javier P é rez-Ilzarbe | 1992 | J Agric Food Chem1992，40，： | 1 |
| 13 | Inhibition of vitellogenin synthesis in Apis mellifera workers by a juvenile hormone analogue, pyriproxyfen显示文摘 | Lucimara Z Pinto Márcia M.G Bitondi Zilá L.P Sim?es | 2000 | Journal of Insect Physiology2000，，2： | 1 |
| 14 | Miller Fisher syndrome in infancy显示文摘 | Julián Benito-León Juan Bravo Fernando Mateos Rogelio Simón | 1996 | Child’s Nervous System1996，，9： | 1 |
| 15 | Myocardial content of selected elements in experimental anthracycline-induced cardiomyopathy in rabbits显示文摘 | Sim(u)nek T Sterba M Holecková M | 2005 | Biometals2005，18，2： | 1 |
| 16 | Tobacco Smoking Increases the Risk for Gastric Adenocarcinoma among Helicobacter pylori -infected Individuals显示文摘 | J. H. Simá n A. Forsgren G. Berglund C.-H. Floré n | 2001 | Scandinavian Journal of Gastroenterology2001，，2： | 1 |
| 17 | Importance of phenolic compounds for the characterization of fruit juices显示文摘 | Brí gida Fern á ndez de Simó n Javier P é rez-Ilzarbe | 1992 | J Agric Food Chem1992，40，： | 1 |
| 18 | Fabric structure and mold curvature effects on preform permeability and mold filling in the RTM process,Part Ⅱ:Predictions and comparisons with experiments显示文摘 | Bickerton S Sozer E M Simácek P Avani S G | 2000 | Composites Part A2000，31，： | 1 |
| 19 | Improvement in quality of life of an oncological patient by laser phototherapy显示文摘 | Campoa L Simōes A Sá Phrn | | 0，，： | 1 |
| 20 | Pyrolysis-GC/MS and TG/MS study of mediated laccase biode lignification of Eucalyptus globulus kraft pulp显示文摘 | Oudia A Mészáros E Sim(o)es R | 2007 | Journal of Analytical and Applied Pyrolysis2007，78，2： | 1 |
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