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您的检索式：作者名="Silvia Ferrini"
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| 1 | Medical treatment for gastro-entero-pancreatic neuroendocrine tumours显示文摘Gastro-entero-pancreatic neuroendocrine neoplasms(GEPNENs) represents a various family of rare tumours. Surgery is the first choice in GEP-NENs patients with localized disease whilst in the metastatic setting many other treatment options are available. Somatostatin analogues are indicated for symptoms control in functioning tumours. Furthermore they may be effective to inhibit tumour progression. GEP-NENs pathogenesis has been extensively studied in the last years therefore several driver mutations pathway genes have been identified as crucial factors in their tumourigenesis. GEP-NENs can over-express vascular endothelial growth factor(VEGF), basic-fibroblastic growth factor, transforming growth factor(TGF-α and-β), platelet derived growth factor(PDGF), insulin-like growth factor-1(IGF-1) and their receptors PDGF receptor, IGF-1 receptor, epidermal growth factor receptor, VEGF receptor, and c-kit(stem cell factor receptor) that can be considered as potential targets. The availability of new targeted agents, such as everolimus and sunitinib that are effective in advanced and metastatic pancreatic neuroendocrine tumours, has provided new treatment opportunities. Many trials combing new drugs are ongoing. | Rossana Berardi Francesca Morgese Mariangela Torniai Agnese Savini Stefano Partelli Silvia Rinaldi Miriam Caramanti Consuelo Ferrini Massimo Falconi Stefano Cascinu | 2016 | World Journal of Gastrointestinal Oncology2016，8，4： | 2 |
| 2 | Natural capital accounting perspectives:a pragmatic way forward显示文摘Introduction:Recent debates surrounding the application of natural capital accounting(NCA)have produced several approaches to further develop this system,as well as highlighted a number of conceptual and methodological issues that need to be resolved before mainstreaming NCA into policy and decision making.We argue that prolonged debate over the value concepts(i.e.,exchange versus other values)underpinning different modifications to NCA has slowed progress in experimentation and uptake by policymakers.Outcomes:Consequently we propose three broad approaches which can be progressed in parallel to reinvigorate experimentation with the NCA principles and practice,while at the same time generating policy relevant tools and evidence bases for decision support.The three approaches are;extended SNA accounting anchored to the use of exchange values;a complementary accounts network(CAN)that utilizes plural values as supplementary accounts to the SNA system;and wealth accounting that focuses on measures of welfare and wellbeing.The three approaches are complementary and data developed in any one can inform the other two.Conclusions:We contend that CAN offers the most flexibility and opportunities to progress short term support for decision making on environmental issues which are now becoming urgent. | Kerry Turner Tomas Badura Silvia Ferrini | 2019 | Ecosystem Health and Sustainability2019，5，1： | 2 |
| 3 | Per-formance of Error Component Models for Status-Quo Effects in ChoiceExperiments显示文摘 | Scarpa Riccardo Silvia Ferrini and Kenneth Willis | 2005 | Applications of simulation methods in environmentaland resource economics2005，6，： | 1 |
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