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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Effects of essential oils on Aedes aegypti larvae: Alternatives to environmentally safe insecticides显示文摘 | W.J. Silva G.A.A. Dória R.T. Maia R.S. Nunes G.A. Carvalho A.F. Blank P.B. Alves R.M. Mar?al S.C.H. Cavalcanti | 2007 | Bioresource Technology2007，，8： | 2 |
| 3 | Neonatal meningitis according to the microbio- logical diagnosis : a decade of experience in a tertiary center 显示文摘 | Bentlin MR Ferreira GL Rugolo LM Silva GH Mondelli AL Rugolo Junior A | 2010 | Arq Neuropsiquiatr2010，68，6： | 1 |
| 4 | Elevated endo-toxin levels in non-alcoholic fatty liver disease显示文摘 | Harte AL da Silva NF Greely SJ | 2010 | J In-flamm(Lond)2010，30，7： | 1 |
| 5 | Behavioral alterations and pro-oxidant effect of a single ketamine administration to mice 显示文摘 | Da Silva FC do Carmo de Oliveira Cito M da Silva MI et al | 2010 | Brain Res Bull2010，83，1： | 1 |
| 6 | Acomparative study of the viscoelastic constitutivemodels for frictionless contact interfaces insolids 显示文摘 | Alves J Peixinho N Da Silva M T? ei al | 2015 | Mechanism and Machine Theory2015，85，： | 1 |
| 7 | Effects of hydrocortisone on microcirculatory alterations in patients with septic shock 显示文摘 | Buchele GL Silva E Ospina-Tascon GA el al | 2009 | Crit Care Med2009，37，4： | 1 |
| 8 | Human papillomavirus can escape immune recognition through Langerhans cell phosphoinositide 3-kinase activation显示文摘 | Fahey LM Silva DMD at al | 2005 | The Journal of Immunology2005，174，： | 1 |
| 9 | Peripheral mineralization of a 3D biodegradable tubular construct as a way to enhance guidance stabilization in spinal cord injury regeneration 显示文摘 | Oliveira AL Sousa EC Silva NA | 2012 | J Mater Sci Mater Med2012，11，： | 1 |
| 10 | RAC1b overexpression in papillary thyroid carcinoma: a role to unravel显示文摘 | Silva AL Carmo F Bugalho MJ | 2013 | Eur J Endocrinol2013，168，6： | 1 |
| 11 | Diarrhea-associated bio- film formed by enteroaggregative Eseherlehia coli and aggrega- tire Citrobaeter freundii: a consortium mediated by putative F pili显示文摘 | Peraira AL Silva TN Gomes A C | 2010 | BMC Microbio12010，10，： | 1 |
| 12 | Elevatedendotoxin levels in non-alcoholic fatty liver disease 显示文摘 | Harte AL da Silva NF Creely SJ | 2010 | JInflamm ( Lond)2010，7，： | 1 |
| 13 | Profile of organ, donorsin Ceara, Northeastern Brazil, from 1998 to 2012显示文摘 | Silva SF Silva SL Nascimento AC al | 2014 | TransplantProc2014，46，6： | 1 |
| 14 | Oral alendronate treatment for se- vere polyostotic fibrous dysplasia due to McCune-Albright syndrome in a child: a case report 显示文摘 | Aragao AL Silva IN | 2010 | Int 3 Pediatr En- docrinol2010，2010，43： | 1 |
| 15 | Sentinel node detection in cervical cancer with (99m)Tc-phytate 显示文摘 | Silva LB Silva-Filho AL Traiman P | 2005 | Gynecol Oncol2005，97，： | 1 |
| 16 | Trypanoso- rrta rangeli: Differential expression of cell surface polypeptide and eeto-phosphatase activity in short and long epimastigote forms显示文摘 | Gonaes SA Fonseca de Souza AL Silva BA | 2006 | Exp Parasitol2006，112，4： | 1 |
| 17 | Software sensors for the monitoring of perfusion cultures: Evaluation of the hybridoma density and the medium composition from glucose concentration measurements 显示文摘 | Pelletier F Fonteix C Da Silva AL | 1994 | Cytotechnology1994，15，13： | 1 |
| 18 | Effect of cement type,relining procedure,and length of cementation on pull-out bond strength of fiber posts显示文摘 | Macedo VC Faria e Silva AL Martins LR | 2010 | J Endod2010，36，9： | 1 |
| 19 | Intra -radicular dentin treatments and retention of fiber posts with self-adhesive resin cements显示文摘 | Faria -E -Silva AL Menezes MS Silva FP | 2013 | Braz Oral Res2013，27，1： | 1 |
| 20 | An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protec- tive by affecting Thl/Th2 polarization 显示文摘 | Weaver A Goncalves da Silva A Nuttall RK et al | 2005 | FASEB J2005，19，12： | 1 |
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