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| 1 | Roles and regulations of the ETS transcription factor ELF4/MEF显示文摘大多数 E26 转变特定(et ) 抄写因素涉及癌症的致病和前进。这是部分地由于在象生长,增长,和区别那样的基本生物进程的 et 抄写因素的角色,并且也因为他们在 tumorigenesis,免疫,和基础细胞的 homoeostasis 有生理的关联的规章的函数。象 E74 一样因素(矮子) 的一个成员 ETS 抄写因素 familymyeloid elf-1-like 因素(MEF ) 的亚科,指定了为 ELF4has 出现极其涉及有免疫力的反应并且发信号,成骨, adipogenesis,癌症,和干细胞静止。ELF4 作为 transcriptional 使活跃之物或通过和它的搭挡蛋白质的相互作用执行这些功能。在 ELF4 的变化引起异常相互作用并且导致可以导致 diseased 房间的下游的过程。知道 ELF4 怎么在某些细胞的过程上侵犯并且它怎么在房间被调整能导致调制 ELF4 活动的生理、病理学的后果的更好的理解。 | Mary Ann Suico Tsuyoshi Shuto Hirofumi Kai | 2017 | Journal of Molecular Cell Biology2017，9，3： | 5 |
| 2 | Computed tomography perfusion imaging as a potential imaging biomarker of colorectal cancer显示文摘Neovascularization was reported to arise early in the adenoma-carcinoma sequence in colorectal cancer(CRC),and the importance of angiogenesis in cancer progression has been established.Computed tomography(CT)perfusion(CTP)based on high temporal resolution CT images enables evaluation of hemodynamics of tissue in vivo by modeling tracer kinetics.CTP has been reported to characterize tumor angiogenesis,and to be a sensitive marker for predicting recurrence or survival in CRC.In this review,we will discuss the biomarker value of CTP in the management of CRC patients. | Koichi Hayano Takeshi Fujishiro Dushyant V Sahani Asami Satoh Tomoyoshi Aoyagi Gaku Ohira Toru Tochigi Hisahiro Matsubara Kiyohiko Shuto | 2014 | World Journal of Gastroenterology2014，20，46： | 5 |
| 3 | 为与窒息肠塞痛联系的肠的局部缺血的察觉的动态 CT 的动脉的阶段的用途显示文摘 AIM:To clarify the usefulness of arterial phase scans in contrast computed tomography (CT) imaging of stran-gulation ileus in order to make an early diagnosis. METHODS:A comparative examination was carried out with respect to the CT value of the intestinal tract wall in each scanning phase, the CT value of the content in the intestinal tract, and the CT value of ascites fluid in the portal vein phase for a group in which ischemia was observed (Group Ⅰ) and a group in which ischemia was not observed (Group N) based on the pathological findings or intra-surgical findings. Moreover, a comparative examination was carried out in Group Ⅰ subjects for each scanning phase with respect to average differences in the CT values of the intestinal tract wall where ischemia was suspected and in the intestinal tract wall in non-ischemic areas. RESULTS:There were 15 subjects in Group Ⅰ and 30 subjects in Group N. The CT value of the intestinal tract wall was 41.8 ± 11.2 Hounsfield Unit (HU) in Group Ⅰ and 69.6 ± 18.4 HU in Group N in the arterial phase, with the CT value of the ischemic bowel wall being significantly lower in Group Ⅰ. In the portal vein phase, the CT value of the ischemic bowel wall was 60.6 ± 14.6 HU in Group Ⅰ and 80.7 ± 17.7 HU in Group N, with the CT value of the ischemic bowel wall being significantly lower in Group Ⅰ; however, no significant differences were observed in the equilibrium phase. The CT value of the solution in the intestine was 18.6 ± 9.5 HU in Group Ⅰ and 10.4 ± 5.1 HU in Group N, being signifi-cantly higher in Group Ⅰ. No significant differences were observed in the CT value of the accumulation of ascites fluid. The average difference in the CT values between the ischemic bowel wall and the non-ischemic bowel wall for each subject in Group Ⅰ was 33.7 ± 20.1 HU in the arterial phase, being significantly larger compared to the other two phases. CONCLUSION:This is a retrospective study using a small number of subjects; however, it suggests that there is a possibility that CT scanning in the arterial phase is useful for the early diagnosis of strangulation ileus. | Gaku Ohira Kiyohiko Shuto Tsuguaki Kono Takayuki Tohma Hisashi Gunji Kazuo Narushima Shunsuke Imanishi Takeshi Fujishiro Tohru Tochigi Toshiharu Hanaoka Hideaki Miyauchi Naoyuki Hanari Hisahiro Matsubara Noriyuki Yanagawa | 2012 | World Journal of Radiology2012，4，11： | 2 |
| 4 | Hepatocellular Carcinoma Arising from Nonalcoholic Steatohepatitis: Report of Two Cases显示文摘 | Seikan Hai Shoji Kubo Taichi Shuto Hiromu Tanaka Shigekazu Takemura Takatsugu Yamamoto Akishige Kanazawa Masao Ogawa Kazuhiro Hirohashi Kenichi Wakasa | 2006 | Surgery Today2006，，4： | 2 |
| 5 | Imaging biomarkers for the treatment of esophageal cancer显示文摘Esophageal cancer is known as one of the malignant cancers with poor prognosis.To improve the outcome,combined multimodality treatment is attempted.On the other hand,advances in genomics and other“omic”technologies are paving way to the patient-oriented treatment called“personalized”or“precision”medicine.Recent advancements of imaging techniques such as functional imaging make it possible to use imaging features as biomarker for diagnosis,treatment response,and prognosis in cancer treatment.In this review,we will discuss how we can use imaging derived tumor features as biomarker for the treatment of esophageal cancer. | Koichi Hayano Gaku Ohira Atsushi Hirata Tomoyoshi Aoyagi Shunsuke Imanishi Toru Tochigi Toshiharu Hanaoka Kiyohiko Shuto Hisahiro Matsubara | 2019 | World Journal of Gastroenterology2019，25，24： | 2 |
| 6 | Generation of polyelonal an- tiserum against the growth hormone secretagogue receptor (GHS- R): evidence that the GHS-R exists in the hypothalamus, pituitary and stomach of rats显示文摘 | Shuto Y Shibasaki T Wada K | 2001 | Life Sci2001，68，9： | 1 |
| 7 | The classification ofanatomic variations in the perigastric vessels by dual-phaseCT to reduce intraoperative bleeding during laparoscopicgastrectomy 显示文摘 | Natsume T Shuto K Yanagawa N | 2011 | Surg Endosc2011，25，： | 1 |
| 8 | Roles of CD 14 in LPS-induced liver injury and lethality in mice pretreated with Propionibacterium acnes显示文摘 | Yoshihiro Shuto Masashi Kataoka Yasunori Higuchi | 2004 | Immunology Letters2004，94，： | 1 |
| 9 | Bilateral lobectomy excluding the caudate lobe for giant mesenchymal hamartoma of the liver显示文摘 | Shuto T Kinoshita H Yamada C | 1993 | Surgery1993，113，2： | 1 |
| 10 | Hepatocellular carcinoma arising from non-alcoholic steatohepatitis:report of two cases显示文摘 | Hai S Kubo S Shuto T | 2006 | Surg Today2006，36，4： | 1 |
| 11 | Influence of histological inflammatory activity on regenerative capacity of liver after percutaneous transhepatic portal vein embolization显示文摘 | Hiromu Tanaka Kazuhiro Hirohashi Shoji Kubo Takashi Ikebe Tadashi Tsukamoto Hiroyuki Hamba Taichi Shuto Kenichi Wakasa Hiroaki Kinoshita | 1999 | Journal of Gastroenterology1999，，1： | 1 |
| 12 | Diffusion-weighted MR imaging for postoperative nodal recurrence of esophageal squamous cell cancer in comparison with FDG-PET显示文摘 | Shuto K Saito H Ohira G | 2009 | Gan To Kagaku Ryoho2009，36，12： | 1 |
| 13 | The accuracy of socket orientation using a pelvic fixationd evice for total hip arthroplasty with the patient in the lateral position in comparison to the vacuum bag fixation method显示文摘 | Hayashi T Jingushi S Shuto T | 2007 | Fukuoka Igaku Zasshi2007，1，： | 1 |
| 14 | A phase I / Il study of second-line chemotherapy with fractionated docetaxel and nedaplatin for 5-FUlcisplatin-resistant esophageal squamous cell carcinoma 显示文摘 | Akutsu Y Shuto K Kono T | 2012 | Hepatogastroenterology2012，59，119： | 1 |
| 15 | Chnicopathologie features and outcome after liver resection for hepatocellular carcinoma in patients with concurrent versus previous chronic hepatitis B 显示文摘 | Kubo S Tanaka H shuto T | 2005 | Surg Today2005，35，3： | 1 |
| 16 | Treatment strategy for metastatic brain tumors from renal cell carcinoma: selection of gamma knife surgery or craniotomy for control of growth and peritumoral edema 显示文摘 | Shuto T Matsunaga S Suenaga J | 2010 | Neurooncol2010，98，： | 1 |
| 17 | Basic fibroblast growth factor inhibits osteoclast - like cell formation显示文摘 | Shuto T Ikebe T | 1996 | J Cell Phys1996，168，： | 1 |
| 18 | Attractants form a vector,Monochamusalternatus,for the pine wood nematode显示文摘 | Shuto Y Watanabe H | 1987 | Agricultural and Biological Chemistry1987，51，： | 1 |
| 19 | Role of Perfusion CT in Assessing Tumor Blood Flow and Malignancy Level of Gastric Cancer显示文摘 | Satoh A Shuto K Okazumi S | | 0，，04： | 1 |
| 20 | Gamma knife radiosurgery for central neurocytomas显示文摘 | Matsunaga S Shuto T Suenaga J | 2010 | Neurol Med Chir(Tokyo)2010，50，2： | 1 |
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