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| 1 | Epidemiology of inflammatory bowel disease in South America: A systematic review显示文摘BACKGROUND The worldwide epidemiology of inflammatory bowel disease(IBD)is rapidly changing.Increasing Crohn’s disease(CD)and ulcerative colitis(UC)incidence and prevalence have been recorded in developing regions such as Asia,Africa and Eastern Europe where it was previously thought to be uncommon.Whether this is also the case in South America is not well known.Demonstration that developing regions worldwide have increasing IBD incidence would indicate that environmental change plays a significant role in the development of IBD.AIM To report the incidence,prevalence and disease characteristics of CD and UC within the South American continent.METHODS A systematic review was conducted by searching published studies in major international and regional databases(MEDLINE,EMBASE and Scopus)between January 1990 and December 2018.Outcomes considered were incidence,prevalence,phenotype,environmental and genetic factors,ethnicity and gender.A pair of independent reviewers screened and reviewed all identified articles.RESULTS One hundred and sixty two citations were initially retrieved with 18 studies included in this systematic review.The majority of included studies were from Brazil(n=13,72%).The incidence of UC ranged from 4.3-5.3/100000 personyears whilst the incidence of CD ranged from 0.74-3.5/100000 person-years.Prevalence ranged from 15.0-24.1/100000 inhabitants for UC and from 2.4-14.1/100000 inhabitants for CD.The incidence and prevalence of both UC and CD has increased significantly in Brazil over the past 21 years.Pancolitis was the most common disease distribution in patients with UC whilst colonic involvement was the most common distribution in CD.People residing in urban areas were at higher risk of developing both CD and UC.CONCLUSION The IBD burden in South America is increasing at a rate possibly even greater than other developing regions around the world.There is a paucity of highquality epidemiological studies and further robust and representative data are required to further explore modifiable risk factors and disease phenotypes. | Sriharan Selvaratnam Santiago Gullino Lisa Shim Eric Lee Alice Lee Sudarshan Paramsothy Rupert W Leong | 2019 | World Journal of Gastroenterology2019，25，47： | 5 |
| 2 | Inner ear anomalies in cochlear implantees: importance of radiologic measurements in the classification 显示文摘 | Shim H J Shill J E Chung J W | 2006 | Otol Neurotol2006，27，6： | 1 |
| 3 | Effect of modification with HNO3 and NaOH on metal adsorption by pitch-based active carbon fibers显示文摘 | Park S J Ryu S K | 2001 | Carbon2001，39，： | 1 |
| 4 | Effects of moisture on properties of epoxy molding compounds 显示文摘 | LU M G SHIM M J KIM S W | 2001 | J Appl Polym Sci2001，81，： | 1 |
| 5 | Solution to the positive real control problem for linear time-invariant systems显示文摘 | SUN W KHARGONEKAR P P SHIM D | 1994 | IEEE Trans Automat Contr1994，39，10： | 1 |
| 6 | Changes in activity of hepatic xenobiotic-metabolizing enzymes of tiger puffer ( Takifugu rubripes ) exposed to paralytic shellfish poisoning toxins 显示文摘 | Jeon J K Lee J S Shim W J | 2008 | Journal of Environmental Biology2008，29，4： | 1 |
| 7 | Block diagonal-ization for muhi-user MIMO with other-cell interference 显示文摘 | SHIM S KWAK J S HEATH R W | 2008 | IEEE Transactions on Wireless Communications2008，7，7： | 1 |
| 8 | Using Phase Change Materials in Clothing 显示文摘 | Shim H McCullough E A Jones B W | 2001 | Textile Research Journal2001，71，6： | 1 |
| 9 | Synthesis and Spectral Study ofLow Dimensional Poly-yne Polymers Containing Phthalocya-nine Silicon and Dimethyl Silicon in the Polymer Backbone显示文摘 | Shim I W Risen W M | 1984 | Journal of Organometallic Chemistry1984，260，2： | 1 |
| 10 | Crack identification using hybrid Neuro-genetic technique 显示文摘 | Suh M W Shim M B Kim M Y | 2000 | Journal of Sound and Vibration2000，238，4： | 1 |
| 11 | Block diagonalization for multi-user MIMO with other-cell interference显示文摘 | SHIM S KWAK J S HEATH R W | 2008 | IEEE Trans Wireless Commun2008，7，7： | 1 |
| 12 | Seasonal flux ofnonylphenonol in Han River, Korea 显示文摘 | Li D H Kim M Shim W J | 2004 | Chemosphere2004，56，1： | 1 |
| 13 | Synthesis of liquid crystalline epoxy and its mechanical and electri- cal characteristics-curing reaction of LCE with diamines by DSC analysis显示文摘 | Lee J Y Shim M J Kim S W | 2001 | Mater Chem Phys2001，59，： | 1 |
| 14 | Effect of modification with HNO3 and NaOH on metal adsorption by pithch-based activated carbon fibers 显示文摘 | Shim J W ark S J Ryu S K | 2001 | Carbon2001，39，： | 1 |
| 15 | Nucleation of Intragranular Ferrite at Ti2O3 Particle in Low Carbon Steel 显示文摘 | Shim J H Cho Y W Chung S H | 1999 | Acta Mater1999，47，9： | 1 |
| 16 | Solution to the positive real control problem for linear time-invariant systems 显示文摘 | Khargonekar P P Shim D | 1994 | IEEE Trans on Automatic Control1994，39，10： | 1 |
| 17 | Numerical simulation of the drop impact response of a portable electronic product显示文摘 | Teo Y M Shim V P W | 2002 | IEEE Transactions on Advanced Packaging Technology2002，25，3： | 1 |
| 18 | Regulation of fumonisin B Biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gent, FCCI显示文摘 | Shim W B Woloshuk C P | 2001 | Applied environmental microbiology2001，67，4： | 1 |
| 19 | Anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb extract on murine cell lines and OVA-induced airway inflammation显示文摘 | KIM J J JIANG J SHIM D W | 2012 | Journal of Ethnopharmacology2012，140，2： | 1 |
| 20 | Assessment ofTBT and organic booster biocide contamination inseawater from coastal areas of South Korea显示文摘 | Kim N S Shim W J Yim U H | 2014 | MarinePollution Bulletin2014，78，12： | 1 |
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