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| 1 | Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice显示文摘 | ALTAY O HASEGAWA Y SHERCHAN P | 2012 | Crit Care Med2012，40，： | 1 |
| 2 | Controversies and Evolving New Mechanisms in Subarachnoid Hemorrhage 显示文摘 | Chen S Feng H Sherchan P | 2014 | Progress in neurobiology2014，115，： | 1 |
| 3 | Controversies and evolving new mechanisms in subarachnoid hemorrhage 显示文摘 | Sheng Chen Hua Feng Prativa Sherchan | 2014 | Progress in Neurobiology2014，115，： | 1 |
| 4 | Cannabinoid receptor type 2 agonist attenuates acute neurogenic pulmonary edema by prevent- ing neutrophil migration after subaraehnoid hemorrhage in rats 显示文摘 | Fujii M Sherchan P Soejima Y | 2016 | Aeta Neuroehir Suppl2016，121，： | 1 |
| 5 | Synthesis, cytotoxicity and structure-activity relationship study of terpyridines显示文摘 | Zhao L Sherchan J Park J K | 2006 | Arch Pharmacol Res2006，29，12： | 1 |
| 6 | Surgical brain injury and edema prevention 显示文摘 | Sherchan P Kim CH Zhang JH | 2013 | ActaNeurochir Suppl2013，118，： | 1 |
| 7 | Assessing placement of nasoduodenal tube its usefulness in maintaining nutrition in critically ill patients显示文摘 | Nayak S K Sherchan M | 2008 | Nepal Med Coll J2008，10，4： | 1 |
| 8 | Tyrosine phos- phatase inhibition attenuates early brain injury after sub- arachnoid hemorrhage in rats显示文摘 | Hasegawa Y Suzuki H Sherchan P | 2011 | Acta Neurochir Suppl2011，110，1： | 1 |
| 9 | Minocyefine improves functional outcomes, memory deficits, and histopathology after endovaseular perforation-induced subarachnoid hemorrhage in rats 显示文摘 | Sherchan P Lekic T Suzuki H | 2011 | J Neurotrauma2011，28，12： | 1 |
| 10 | Controversies and evolving new mechanisms in subarachnoid hemorrhage 显示文摘 | Chert S Feng H Sherchan P | 2014 | Prog Neurobiol2014，115，： | 1 |
| 11 | Cannabinoid receptor type 2 agonist attenuates apoptosis by activation of phosphory- lated CREB-Bcl-2 pathway after subarachnoid hemorrhage in rats 显示文摘 | Fujii M Sherchan P Soejima Y | 2014 | Exp Neurol2014，261，： | 1 |
| 12 | Intravas- cular catheter-related infections in an Indian tertiary care hospital显示文摘 | Parameswaran R Sherchan JB Varma DM | 2011 | J lnfect Dev Ctries2011，5，6： | 1 |
| 13 | Intravas- cular catheter-related infections in an Indian tertiary care hospital显示文摘 | Parameswaran R Sherchan JB Varma DM | 2011 | J lnfect Dev Ctries2011，5，6： | 1 |
| 14 | Controversies and evolving new mechanisms in subarachnoid hemorrhage显示文摘 | Chen S Feng H Sherchan P | 2014 | Progress Neurobiol2014，115，： | 1 |
| 15 | Controversies and evolving new mechanisms in subarachnoid hemorrhage显示文摘 | Chen S Feng H Sherchan P et aI | 2014 | Prog Neuro- biol2014，115，： | 1 |
| 16 | Assessing placement of nasoduodenal tube and its usefulness in maintaining nutrition in critically ill patients显示文摘 | Nayak SK Sherchan M Durra Poudel S | 2008 | Nepal Med Coll J2008，10，4： | 1 |
| 17 | Racial disparities in immune-related adverse events of immune checkpoint inhibitors and association with survival based on clinical and biochemical responses显示文摘BACKGROUND Immune checkpoint inhibitors(ICPi)cause various immune-related adverse events(irAE)with thyroid dysfunction as a commonly reported abnormality.There is increasing evidence showing positive association with development of irAE and survival.However,prior trials with ICPi had underrepresentation of minorities with<5%African Americans.AIM To evaluate the association between development of irAE and survival outcomes among a racially diverse patient population.METHODS Data on patients with stage IV solid malignancies treated with programmed cell death-protein 1/programmed death ligand 1 blockers between January 2013 and December 2018 across MedStar Georgetown Cancer Institute facilities were retrospectively reviewed.Patients treated with cytotoxic T-lymphocyte-associated protein 4 inhibitors were excluded.Progression free survival(PFS)and overall survival(OS)were primary endpoints and were calculated using Kaplan-Meier methods and Wilcoxon rank sum test for comparison.RESULTS Out of 293 patients who met eligibility criteria,91 pts(31%)had any grade irAE;most common AE were endocrine(40.7%)specifically TSH elevation,dermatological(23.1%)and rheumatologic(18.7%).Proportion of irAE was significantly higher in Caucasians vs African Americans(60.4%vs 30.8%),in patients with low programmed death ligand 1,lower LDH,older age,and those who had more treatment cycles with ICPi.Rate of progression was lower in patients with irAE(30.8%vs 46.0%,P=0.0140).Median PFS(5.8 vs 3.0 mo,P=0.0204)and OS(17.1 vs 7.2 mo,P<0.0001)were higher with irAE.Statistically significant difference in OS(17.1 vs 8.6 mo,P=0.0002)but not in PFS(5.8 vs 3.3 mo,P=0.0545)was noted with endocrine irAE.No differences in survival were observed among other commonly reported irAE.Differences in survival among subgroups of patients with irAE are described.CONCLUSION Development of irAE positively correlated with improved PFS and OS as reported in previous studies.To our knowledge,this is the first study observing differences in OS favoring endocrine AE and Caucasian race.These factors may be potential surrogate markers of prognosis pending replication of these results in large-scale studies. | Monica Peravali Cristiane Gomes-Lima Eshetu Tefera Mairead Baker Mamta Sherchan Saira Farid Kenneth Burman Florina Constantinescu Irina Veytsman | 2021 | World Journal of Clinical Oncology2021，12，2： | 1 |
| 18 | A survey of trust in social networks显示文摘 | SHERCHAN W NEPAL S PARIS C | 2013 | ACM Computing Surveys2013，45，4： | 1 |
| 19 | A survey of trust in social networks 显示文摘 | SHERCHAN W NEPAL S PARIS C | 2013 | ACM Computing Sur- veys2013，45，4： | 1 |
| 20 | Controversies and e- volving new mechanisms in subarachnoid hernorrhage显示文摘 | Chen S Feng H Sherchan P et aI | 2014 | Prog Neurobiol2014，115，2： | 1 |
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