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| 1 | Preliminary assessing no-surgical treatment response in bronchogenic carcinoma with double-phase contrast material-enhanced computed tomography显示文摘评估双阶段的功效的目的在 preliminarily 在 bronchogenic 癌估计没有外科的治疗反应对比提高材料的计算断层摄影术(CT ) 。有在没有外科的治疗以后的 bronchogenic 癌的 52 个病人经历了双阶段的方法对比提高材料的计算断层摄影术。在非离子的对比材料经由赌注被管理以后,二螺线 CT 扫描分别地在 25 和 90 秒点被获得以由使用一个汽车注射者的 4 mL/s 的率的肘的静脉。每扫描上的 Precontrast 和柱子对比变细被记录,山峰高度是计算的。改进模式在在对比媒介的注射以后在 25 和 90 秒点获得的图象上被评估。结果 Precontrast 变细,在 25 和 90 秒点的柱子对比变细是 42.20 ± 7.43 胡, 57.35 ± 10.09 胡和 71.85 ± 12.45 胡分别地。在 precontrast 变细的统计上重要的差别都没在我们在治疗前在情况中被获得的旧学习(吝啬的 precontrast 变细 40.70 胡) 在学习和结果在我们的结果之间被发现(t = 1.455, P = 0.152 >
0.05 ) 。在没有外科的治疗以后的 bronchogenic 癌的山峰高度(29.46 ± 10.85 胡) 是比在在我们的旧学习获得的治疗前的 bronchogenic 癌的显著地低的(吝啬的山峰高度 35.79 胡;t = 4.206, P = 0.001 <
0.05 ) 。52 个盒子中的 32 个在 90 秒点显示出同类的改进。32 个盒子,与不同类的改进有 21, 7 与不同类的改进, 2 与中央改进并且 2 与在 25 秒点的外部改进。在没有外科的处理以后的结论 Bronchogenic 癌在对比材料的管理以后显示出渐渐的增加到山峰高度。山峰高度能反映 bronchogenic 癌的血供应并且可能是为在 bronchogenic 癌的没有外科的治疗反应的评估的索引。 | Shenjiang Li Yong Zhao Yan Zhu Feng Zhu Debin Liu Wenjie Liang Xuefeng Cui Wenjie Bi | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，3： | 9 |
| 2 | Correlation of the quantifiable parameters of blood flow pattern derived with dynamic CT in solitary bronchogenic adenocarcinoma显示文摘Objective:To evaluate the correlation of the quantifiable parameters of blood flow pattern derived with dynamic CT in solitary bronchogenic adenocarcinoma(SBA).Methods:46 patients with solitary bronchogenic adenocarcinomas (SBA)(diameter≤4 cm)underwent multi-location dynamic contrast material-enhanced(nonionic contrast material was administrated via the antecubital vein at a rate of 4 mL/s by using an autoinjector 90 mL,4×5 mm or 4×2.5 mm scanning mode with stable table were performed)serial CT.Precontrast and postcontrast attenuation on every scan was recorded.Perfusion (PBA),peak height(PHBA),ratio of peak height of the SPN to that of the aorta(BA-to-A ratio)and mean transit time(MTT)were calculated.The correlation between peak height of the aorta(PHA)and parameters of the SBA(PHBA,BA-to-A ratio,PBA,and MTT)and those among parameters of the SBA were assessed by means of linear regression analysis.Regression equation among parameters of the SBA were obtain by means of stepwise regression.Results:The correlation between the SBA peak height(PHBA,36.78 HU±12.02)and the aortic peak height(PHA)was significant(r=0.506,P<0.0001).No significant cor- relation was found between the BA-to-Apeak height ratio(15.33%±4.55)and the aortic peak height(r=0.130,P=0.388> 0.05)as it was between the SBA perfusion(PBA,31.86 mL/min/100 g±9.74)and the aortic peak height(r=0.049,P=0.749 >0.05).The SBA perfusion correlated with the PHBA and the BA-to-A peak height ratio(r=0.394,P=0.007<0.05;r=0.407, P=0.005<0.05).The PHBA correlated positively with the BA-to-A peak height ratio(r=0.781,P<0.0001).Mean transit time was 14.84 s±5.52.PBA=18.500+0.872×BA-to-A ratio.BA-to-A ratio=4.467+0.295×PHBA.Conclusion:The linear correlation between the SBA perfusion and BA-to-Aratio and that between BA-to-Aratio and PHBA can be expressed by equation. It is possible to design a simpler scanning procedure of investigation of bronchogenic adenocarcinoma angiogenesis. | Shenjiang Li Xiangsheng Xiao Shiyuan Liu Huimin Li Chengzhou Li Chenshi Zhang | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，4： | 8 |
| 3 | Correlation between the quantifiable parameters of blood flow pattern derived with dynamic CT in malignant solitary pulmonary nodules and tumor size显示文摘Objective: To evaluate the correlation between the quantifiable parameters of blood flow pattern derived with dy- namic CT in malignant solitary pulmonary nodules and tumor size. Methods: Sixty-eight patients with malignant solitary pulmo- nary nodules (SPNs) (diameter ≤4 cm) underwent multi-location dynamic contrast material-enhanced (nonionic contrast material was administrated via the antecubital vein at a rate of 4mL/s by using an autoinjector, 4×5 mm or 4×2.5 mm scanning mode with stable table were performed). Precontrast and postcontrast attenuation on every scan was recorded. Blood flow (BF), peak, height (PHSPN), ratio of peak height of the SPN to that of the aorta (SPN-to-A ratio) and mean transit time (MTT) were calculat- ed. The correlation between the quantifiable parameters of blood flow pattern derived with dynamic CT in malignant solitary pul- monary nodules and tumor size were assessed by means of linear regression analysis. Results: No significant correlations were found between the tumor size and each of the peak height (PHSPN) (35.79±10.76 Hu), ratio of peak height of the SPN to that of the aorta (SPN-to-A ratio), (14.27%±4.37) and blood flow (BF) (30.18 mL/min/100 g±9.58) (r=0.180, P=0.142>0.05; r=0.205, P=0.093>0.05; r=0.008, P=0.947>0.05). Conclusion: No significant correlations were found between the tumor size and each of the quantifiable parameters of blood flow pattern derived with dynamic CT in malignant solitary pulmonary nodules. | Shenjiang Li Xiangsheng Xiao Shiyuan Liu Huimin Li Chengzhou Li Chenshi Zhang | 2006 | The Chinese-German Journal of Clinical Oncology2006，5，5： | 3 |
| 4 | 显示恶性孤立肺结节分叶征的理想CT层厚(英文)显示文摘Objective: The aim of this study was to determine an optimal slice thickness that was efficient in revealing lobulation of malignant solitary pulmonary nodules (SPNs) on multi-slice spiral computed tomography (MSCT) images preliminarily. Methods: Fifty patients with malignant SPNs (diameter ≤ 3 cm) underwent multidetector-row computed tomography of the chest in a single-breath-hold technique. The raw data were acquired with a collimation of 0.625 mm. Three sets of contiguous images were reconstructed with 1-, 2-, and 5-mm slice thickness, respectively. The lobulation sign of SPNs on the computed tomography (CT) images presented in 1-, 2-, and 5-mm slice thickness was compared. Using the 1-mm sections as the gold standard, an optimal slice thickness in revealing lobulation sign of SPNs was determined. Results: The 1-mm-thick images CT revealed 98 lobulations (25 with chord distance < 1 mm; 30 with chord distance 1-2 mm; 43 with chord distance > 2 mm) of 45 malignant SPNs. 18 lobulations with chord distance < 1 mm presented in 2-mm-thick sections were as same as those in 1-mm-thick sections. Statistically significant difference in lobulations number was found between that revealed in 2-mm-thick images and that in 1-mm-thick images (P = 0.023 < 0.05). 16 lobulations with chord distance < 1 mm presented in 5-mm-thick sections were as same as that in 1-mm-thick sections. There was statistically significant difference in lobulations number between that revealed in 5-mm-thick images and that in 1-mm-thick images (P = 0.004 < 0.05). The 24 lobulations with chord distance 1-2 mm presented in 2-mm-thick sections were as same as that in 1-mm-thick sections. No statistically significant difference in lobulations number were found between that revealed in 2-mm-thick images and that in 1-mm-thick images (P = 0.261 > 0.05). 13 lobulations with chord distance 1-2 mm presented in 5-mm-thick sections were as same as that in 1-mm-thick sections. There was statistically significant difference in lobulations number between that revealed in 5-mm-thick images and that in 1-mm-thick images (P = 0.003 < 0.05). 40 lobulations with chord distance ﹥2 mm presented in 2-mm-thick sections were as same as that in 1-mm-thick sections. No statistically significant difference in lobulations number was found between that revealed in 2-mm-thick images and that in 1-mm-thick images (P = 0.631 > 0.05). 36 lobulations with chord distance ﹥2 mm presented in 5-mm-thick sections were as same as that in 1-mm-thick sections. There was no statistically significant difference in lobulations number between that revealed in 5-mm-thick images and that in 1-mm-thick images (P = 0.264 > 0.05). Conclusion: It is suggested that the use of 1-mm slice thickness is suitable in revealing lobulations with chord distance < 1 mm. A 2-mm slice thickness is suggested to be used in revealing lobulations with chord distance 1-2 mm and 5-mm slice thickness to be used in revealing lobulations with chord distance > 2 mm. | Shenjiang Li Changcheng Li Xin Wang Debin Liu Wenjie Liang Feng Zhu Yan Zhu Xuefeng Cui Wenjie Bi | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，10： | 2 |
| 5 | Research on oil-free air scroll compressor with high speed in 30 kW fuel cell 显示文摘 | Zhao Yuanyang Li Liansheng ShenJiang etal | 2003 | Applied Thermal Engineering2003，23，10： | 1 |
| 6 | 明显强化孤立肺结节血流模式(英文)显示文摘Objective: To evaluate the efficacy of dynamic multi-slice spiral computed tomography (MSCT) for providing quantitative information about blood flow patterns of solitary pulmonary nodules (SPNs). Methods: Seventy-eight patients with SPNs (diameter ≤ 4 cm; 68 malignant; 10 active inflammatory) were underwent multi-location dynamic contrast mate-rial-enhanced serial CT (nonionic contrast material was administrated via the antecubital vein at a rate of 4 mL/s by using an autoinjector, 4 × 5 mm or 4 × 2.5 mm transverse scanning mode with stable table were performed). Sixteen series CT scans (16 scans each for the first and second series and one scan each for the rest series) were obtained during 9 min scanning period. Precontrast and postcontrast attenuation on every scan was recorded. Perfusion, peak height and ratio of peak height of the SPN to that of the aorta were calculated. Perfusion was calculated from the maximum gradient of the time-attenuation curve and the peak height of the aorta. Results: No statistically significant difference in the peak height was found between malignant (35.79 ± 10.76 Hu) and active inflammatory (39.76 ± 4.59 Hu) (t = 1.148, P = 0.255 > 0.05). SPN-to-aorta ratio (14.27% ± 4.37) and perfusion value (30.18 mL/min/100 g ± 9.58) in malignant SPNs were significantly lower than those of active inflammatory (18.51% ± 2.71, 63.44 mL/min/100 g ± 43.87) (t = 2.978, P = 0.004 < 0.05; t = 5.590, P < 0.0001). Conclusion: The quantitative information about blood flow patterns of malignant and active inflammatory SPNs is different . SPN-to-aorta ratio and perfusion value are helpful in differentiating malignant nodules from active inflammatory. | Shenjiang Li Xiangsheng Xiao Shiyuan Liu Huimin Li Chengzhou Li Chenshi Zhang | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，5： | 1 |
| 7 | 孤立性肺腺癌血管生成与血流模式初步研究:影像-病理对照(英文)显示文摘Objective: To investigate the correlations of vascular endothelial growth factor (VEGF)-positive tumor angiogenesis and the quantifiable parameters of blood flow pattern derived with dynamic CT in solitary bronchogenic adenocarcinoma. Methods: 30 patients with VEGF-positive bronchogenic adenocarcinomas (diameter ≤ 4 cm) underwent multi-location dynamic contrast material-enhanced (nonionic contrast material was administrated via the antecubital vein at a rate of 4 mL/sec by using an autoinjector) serial CT. The quantifiable parameters (Perfusion, peak height, ratio of peak height of the bronchogenic adenocarcinoma to that of the aorta and mean transit time) of blood flow pattern derived with dynamic CT in solitary bronchogenic adenocarcinoma were compared with microvessel densities (MVDs) and VEGF expression by immunohistochemistry. Results: Peak height of VEGF-positive bronchogenic adenocarcinoma was 36.06 HU ± 13.57 HU, bronchogenic adenocarcinoma-to-aorta ratio 14.25% ± 4.92, and perfusion value 29.66 ± 5.60 mL/min/100 g , mean transit time 14.86 s ± 5.84 s, and MVD 70.15 ± 20.03. Each of peak height, ratio of peak height of the bronchogenic adenocarcinoma to that of the aorta and perfusion correlated positively with MVD (r = 0.781, P < 0.0001; r = 0.688, P < 0.0001; r = 0.716, P < 0.0001; respectively). No significant correlation was found between mean transit time and MVD (r = 0.260, P = 0.200 > 0.05). Conclusion: Perfusion, peak height and ratio of peak height of the bronchogenic adenocarcinoma to that of the aorta reflect MVD in VEGF-positive bronchogenic adenocarcinoma. Perfusion, peak height and ratio of peak height of the bronchogenic adenocarcinoma to that of the aorta derived with dynamic CT might be index for VEGF-related tumor angiogenesis in bronchogenic adenocarcinoma. | Shenjiang Li Xiangsheng Xiao Shiyuan Liu Huimin Li Chengzhou Li Chenshi Zhang | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，9： | 0 |
| 8 | CT增强在肺癌非手术治疗疗效评价中的作用(英文)显示文摘Objective:The aim of the study was to evaluate the efficacy of contrast material-enhanced computed tomography(CT) in assessing no-surgical treatment response in bronchogenic carcinoma.Methods:The 67 patients with bronchogenic carcinoma after no-surgical treatment underwent two-phase contrast material-enhanced computed tomography.Two spiral CT scans were obtained at 25 and 90 s respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 4 mL/s by using an autoinjector.Precontrast and postcontrast attenuation values on every scan were recorded and peak height was calculated.Enhancement pattern was evaluated on the image obtained at 25 and 90 s after injection of contrast medium.Results:Precontrast attenuation value,postcontrast attenuation values at 25 and 90 s were(41.26 ± 7.77) Hu,(56.45 ± 10.48) Hu,(70.82 ± 11.99) Hu,respectively.No statistically significant difference in precontrast attenuation was found between our results in this study and the results in our old study(mean precontrast attenuation 40.70 Hu) which was obtained in cases without any therapy(t = 0.593,P = 0.555﹥0.05).Peak height of bronchogenic carcinoma after no-surgical treatment [(29.40 ± 10.73) Hu] were significantly lower than that of bronchogenic carcinoma without any therapy obtained in our old study(mean peak height 35.79 Hu)(t =-4.874,P = 0.001 < 0.05).The 39 among 67 cases appeared homogeneous enhancement at 90 s.At 25 s,there were 26 cases with inhomogeneous enhancement,9 cases with homogeneous enhancement,2 cases with central enhancement,and 2 cases with peripheral enhancement among the 39 cases.Conclusion:Peak heights can reflect the blood supply of bronchogenic carcinoma and might be an index for evaluation of no-surgical treatment response in bronchogenic carcinoma. | Shenjiang Li Feng Zhu Yan Zhu Debin Liu Wenjie Liang Xuefeng Cui Wenjie Bi | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，5： | 0 |
| 9 | 强化区大小的变化在肺癌非手术治疗疗效评价中作用的初步探讨(英文)显示文摘Objective:The aim of this study was to evaluate the efficacy of changes in the sum of the enhancement area longest diameters(LD) in assessing no-surgical treatment response in bronchogenic carcinoma preliminarily.Methods:Twentytwo patients with bronchogenic carcinoma underwent two-phase contrast material-enhanced computed tomography prior to and after stopping no-surgical treatment more than one-month respectively.Two spiral CT scans were obtained at 25 and 90 sec respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 3 mL/sec by using an autoinjector.The sum of the tumor LD prior to treatment,after treatment and the sum of the post-treatment tumor enhancement area LD on the images obtained at 90 sec after injection of contrast medium were recorded.Enhancement pattern was evaluated on the images obtained at 25 and 90 sec after injection of contrast medium.Response Evaluation Criteria In Solid Tumors(RECIST) guidelines were adopted to evaluate treatment response.The significance of the difference among groups was analyzed by means of ANOVA.Results:The sum of the tumor LD prior to treatment,that of after treatment and the sum of the post-treatment tumor enhancement area LD on the images obtained at 90 sec after injection of contrast medium were(4.48 ± 1.19),(3.98 ± 1.50),(3.35 ± 1.11) cm respectively and there were statistically significant differences among them(F = 4.273,P = 0.018).The sum of the tumor LD prior to treatment was significantly higher than that of the post-treatment tumor enhancement area(P = 0.005).No statistically significant difference in the sum of the tumor LD was found between the pre-treatment and the post-treatment(P = 0.203).There was not statistically significant difference between the sum of the tumors LD prior to treatment and that of after treatment.According to changes in sum of the tumor LD,there were 4 of 22(18.18%) partial responses(PRs),14 of 22(63.64%) stable diseases(SDs),4 of 22(18.18%) progressive diseases(PD) and response rate was 18.18%.According to changes in the sum of the post-treatment tumor enhancement area LD on the images obtained at 90 sec after injection of contrast medium,there were 5 of 22(22.73%) PRs,15 of 22(68.18%) SDs,2 of 22(9.09%) PDs and response rate was 22.73%.Ten cases among 22 appeared homogeneous enhancement at 90 sec prior to treatment.At 25 sec,there were 6 cases with heterogeneous enhancement,2 cases with homogeneous enhancement,1 case with central enhancement,and 1 case with peripheral enhancement among the 10 cases.Six cases appeared homogeneous enhancement and 16 cases heterogeneous enhancement at 90 sec after treatment.At 25 sec,there were 3 cases with heterogeneous enhancement,2 cases with homogeneous enhancement,and 1 case with central enhancement among the six cases.Conclusion:Therapeutic effect may be underestimated with use of changes in sum of the tumor LD.The changes in sum of tumor enhancement area LD is suggested to be used in assessing no-surgical treatment response in bronchogenic carcinoma.The no-surgical treatment kill bronchogenic carcinoma cell and tumor after no-surgical treatment shows a gradual increase to the peak height after administration of contrast material. | Shenjiang Li | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，7： | 0 |
| 10 | 在PACS与CT工作站评价周围型肺癌强化的对比研究(英文)显示文摘Objective: The aim of the study was to determine the efficiency and effectiveness of picture archiving and communication system(PACS) workstation in detecting enhancement pattern of peripheral bronchogenic carcinoma. Methods: The 62 patients with peripheral bronchogenic carcinoma underwent two-phase contrast material-enhanced multislices computed tomography(MSCT) of the chest in a single-breath-hold technique. Two spiral CT scans were obtained at 25 s and 90 s respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 4 m L/s by using an autoinjector. Precontrast and postcontrast attenuation on every scan were measured on PACS and CT workstations respectively and peak height was calculated. Enhancement pattern was evaluated on the image obtained at 90 s after injection of contrast medium on PACS and CT workstations respectively. Results: No statistically significant difference in precontrast attenuation, postcontrast attenuation at 25 s and 90 s was found between these measured on a PACS workstation [(40.21 ± 7.03) HU;(55.53 ± 11.09) HU;(75.95 ± 13.45) HU] and those [(39.01 ± 8.95) HU;(56.01 ± 10.91) HU;(76.03 ± 11.95) HU] on a CT workstation(t = 1.140, P = 0.256 > 0.05; t = 1.580, P = 0.149 > 0.05; t = 1.505, P = 0.150﹥0.05). The peak height that calculated on a PACS workstation was 35.74 HU(20 HU). There was not statistically significant difference in peak height between that calculated on a PACS workstation and that on a CT workstation [(37.02 ± 12.05) HU; t = 2.001, P = 0.099 > 0.05]. The tumors showed same enhancement pattern on PACS workstation and CT workstation. Of the 62 cases, 38 showed homogeneous enhancement, 17 showed heterogeneous enhancement, five showed peripheral enhancement, two showed central enhancement, at 90 s. The enhancement pattern revealed on PACS workstation was consistent with feature of peripheral bronchogenic carcinoma. Conclusion: The efficiency and effectiveness of PACS workstation is as same as those of CT workstation in detecting enhancement pattern of peripheral bronchogenic carcinoma. | Chunlei Lv Shenjiang Li Changcheng Li Debin Liu Wenjie Liang Feng Zhu Yan Zhu Xuefeng Cui | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，12： | 0 |
| 11 | 强化模式的变化在肺癌非手术治疗疗效评价中作用的初步探讨(英文)显示文摘Objective: The aim of this study was to evaluate the efficacy of changes in enhancement pattern in assessing no-surgical treatment response in bronchogenic carcinoma preliminarily. Methods: Thirty-three patients with bronchogenic carcinoma underwent two-phase contrast material-enhanced computed tomography prior to and after stopping no-surgical treatment more than one-month respectively. Two spiral CT scans were obtained at 25 and 90 s respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 3 mL/s by using an autoinjector. The sum of the tumor longest diameters (LD) prior to treatment, after treatment and the sum of the post-treatment tumor enhancement area LD on the images obtained at 90 s after injection of contrast medium were recorded. Precontrast and postcontrast attenuation on every scan was recorded and peak height was calculated. The significance of the difference among groups was analyzed by means of ANOVA, student t test and chi-square test. Results: The sum of the tumor LD prior to treatment, that of after treatment and the sum of the post-treatment tumor enhancement area LD on the images obtained at 90 s after injection of contrast medium were (4.49 ± 1.32), (4.05 ± 1.63), (3.36 ± 1.22) cm respectively and there were statistically significant dif- ferences among them (f = 5.467, P = 0.006). The sum of the tumor LD prior to treatment was significantly higher than that of the post-treatment tumor enhancement area (P = 0.001). No statistically significant difference in the sum of the tumor LD was found between the pre- treatment and the post-treatment (P = 0.207). There was no statistically significant difference between the sum of the tumors LD and that of tumor enhancement area after treatment (P = 0.086). The response rate (RR) (21.21%) according to changes in sum of the tumor LD was significantly lower than that (30.30%) according to changes in the sum of the post-treatment tumor enhancement area LD ( χ 2 = 15.12, P < 0.05), and the progressive diseases (PD) rate (21.21%) was significantly higher than that (12.12%; χ 2 = 14.12, P < 0.05). No statistically significant difference was found between precontrast attenuation prior to treatment [(41.77±7.03) HU] and that after treatment [(41.89 ± 7.63) HU; t = 0.335, P = 0.740 > 0.05]. Peak height of bronchogenic carcinoma prior to treatment [(36.50 ± 11.21) HU] were significantly higher than that after treatment [(29.91 ± 10.35) HU; t = 10.081, P = 0.001]. Conclusion: Therapeutic effect may be underestimated with use of changes in sum of the tumor LD. The changes in sum of tumor enhancement area LD in addition to peak height is suggested to be used in assessing no-surgical treatment response in bronchogenic carcinoma. | Shenjiang Li Changcheng Li Feng Zhu Yan Zhu Xuefeng Cui Debin Liu Wenjie Liang | 2012 | The Chinese-German Journal of Clinical Oncology2012，11，9： | 0 |
| 12 | 在PACS与CT工作站测量恶性孤立肺结节大小及密度的对比研究(英文)显示文摘Objective: The aim of our study was to determine the efficiency and effectiveness of picture archiving and communication system(PACS) workstation in detecting the sizes and attenuation of malignant solitary pulmonary nodules(SPNs). Methods: Forty patients with malignant SPNs(diameter ≤ 3 cm) underwent multidetector-row computed tomography(CT) of the chest in a single-breath-hold technique. The raw data were acquired with a collimation of 0.625 mm. The diameters and attenuation of malignant SPNs were measured on PACS and CT workstation respectively. The diameter was defined as the average value of the anteroposterior, lateral and superoinferior diameters on CT scans obtained with a mediastinal window setting. The superoinferior diameters were measured on MPR image. The diameters and attenuation of malignant SPNs and spending time in measuring were recorded. Results: The diameters of malignant SPNs measured on a PACS and CT workstation were 2.09 cm ± 0.87 cm, 2.07 cm ± 0.79 cm, respectively. There was not statistically significant difference in the diameters of malignant SPNs between that measured on a PACS workstation and that on a CT workstation(t = 1.580, P = 0.210 > 0.05). The attenuation of malignant SPNs measured on a PACS and CT workstation were 40.15 HU ± 7.53 HU, 39.99 HU ± 8.13 HU, respectively. There was not statistically significant difference in the attenuation of malignant SPNs between that measured on a PACS workstation and that on a CT workstation(t = 1.008, P = 0.298 > 0.05). The spending time in measuring on a PACS and CT workstation were 55 s ± 4.03 s, 56 s ± 3.95 s, respectively. No statistically significant difference was found in spending time in measuring between that on a PACS workstation and that on a CT workstation(t = 0.958, P = 0.315 > 0.05). Conclusion: The efficiency and effectiveness of PACS workstation is as same as those of CT workstation in detecting the sizes and attenuation of malignant SPNs. It is suggested that the size and attenuation of malignant SPNs are measured on a PACS and CT workstation. | Shenjiang Li Cui Li Guangwen Jv Wenjie Liang Changcheng Li Debin Liu Feng Zhu Yan Zhu Xuefeng Cui Liguang Zheng | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，1： | 0 |
| 13 | 消化系统肿瘤CT随访中发现的肝脏高灌注异常的转归(英文)显示文摘Objective: The aim of this study was to investigate progression of hepatic hyperperfusion disorders revealed during follow-up contrast material-enhanced multi-slice spiral computed tomography(MSCT) scan of digestive system neoplasm. Methods: Three-phase contrast material-enhanced MSCT were performed during the follow-up in patients with digestive system malignant tumor confirmed histologically. The progression of hepatic hyperperfusion disorders revealed on contrast material-enhanced CT image were investigated at the 2 years follow-up with approximately 6 months interval. Results: The hepatic hyperperfusion disorders were showed in 39 patients on follow-up contrast material-enhanced MSCT scans. Among the 39 patients, initial hyperperfusion disorders were revealed in 6(15.38%), 26(66.67%), and 7(17.95%) patients in 6, 12, and 18 months during follow-up respectively. The initial hyperperfusion disorders revealed in 12 months were more frequent than those revealed in 6 months(χ2 = 14.82, P < 0.05) and 18 months(χ2 = 15.02, P < 0.05). Among the 39 patients, the hyperperfusion disorders progressed into liver metastasis based on typical CT findings in 37(94.87%) patients, and were not obvious changes in 2(5.13%) patients. Among the 37 patients, the hyperperfusion disorders progressed into metastasis in 10(25.64%) patients in 6 months after the hyperperfusion disorders were revealed, and in 27(69.23%) patients in 12 months. The hyperperfusion disorders developing into metastasis were more in 12 months than those in 6 months(χ2 = 14.98, P < 0.05). Conclusion: Most hepatic hyperperfusion disorders revealed at the follow-up of digestive system neoplasm may be early manifestations of liver metastasis. The careful follow-up of hepatic hyperperfusion disorders is necessary. | Shenjiang Li Wenjie Liang Guangwen Ju Cui Li Changcheng Li Debin Liu Feng Zhu Yan Zhu Xuefeng Cui Liguang Zheng | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，1： | 0 |
| 14 | DT、CT、MRI在骨肿瘤诊断中的临床价值(英文)显示文摘Objective: The aim of the study was to investigate the efficacy of digital radiography(DR), computed tomography(CT) and magnetic resonance imaging(MRI) in bone tumors. Methods: Fifty-five patients with histologically confirmed bone tumors underwent imaging examinations. Fifty-five patients were performed DR, 21 CT and 20 MRI. Results: DR of 51 patients clearly revealed bone changes. DR of 40 patients well showed marginal. Twenty tumors appeared periosteal reaction on DR and 19 calcification on DR. CT scan of 21 patients clearly depicted bone changes, marginal and calcification and CT scan of 8 revealed periosteal reaction. MRI scan of 20 patients all showed marginal and soft-tissue mass and bone marrow edema was prominent in 8 patients. Conclusion: DR is the first imaging approach for born tumors. CT well reveal the extent and minute structure of the bone tumors, the extent, soft-tissue mass and bone marrow edema are more dramatically demonstrated on MRI imaging. DR integrates with CT and MRI, is helpful in diagnosis of bone tumors. | Yanjiao Zhang Xuefeng Cui Changcheng Li Shenjiang Li | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，4： | 0 |
| 15 | MRI增强三期扫描在肺癌非手术治疗疗效评价中的初步研究(英文)显示文摘Objective:The aim of this study was to evaluate the efficacy of three-phase contrast material-enhanced MRI in assessing no-surgical treatment response in peripheral bronchogenic carcinoma preliminarily.Methods:Twenty-two patients with bronchogenic carcinoma after no-surgical treatment underwent three-phase contrast material-enhanced MRI.Three scans were obtained at 25 s,120 s and 180 s respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 2 mL/s by using an autoinjector.Precontrast and postcontrast signal intensity on every scan was recorded.Peak Height(PH) and Maximum Enhancement(Emax) were calculated.Enhancement pattern was evaluated on the images obtained at 120 s and 180 s after injection of contrast medium.Results:Precontrast signal intensity,postcontrast signal intensity at 120 s and 180 s were 478 ± 108,926 ± 209 and 1050 ± 252.PH(571 ± 225) and Emax(119 ± 49) of bronchogenic carcinoma after no-surgical treatment were significantly lower than those of bronchogenic carcinoma without any therapy(mean PH 655,mean Emax 150)(t = 2.178,P = 0.005 < 0.05,t = 4.196,P = 0.001 < 0.05).Six cases among 22 appeared homogeneous enhancement at 180 s.At 120 s,there were 4 cases with inhomogeneous enhancement,1 case with homogeneous enhancement,1 case with peripheral enhancement among the 6 cases.Conclusion:Bronchogenic carcinoma after no-surgical treatment shows a gradual increase to the PH after administration of contrast material.Three-phase contrast material-enhanced MRI can reflect the blood supply of bronchogenic carcinoma and might be effective approach for evaluation of no-surgical treatment response in bronchogenic carcinoma. | Shenjiang Li Xuefeng Cui Debin Liu Wenjie Liang Yan Zhu Wenjie Bi | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，8： | 0 |
| 16 | 显示肺结节累及支气管理想CT层厚的初步探讨(英文)显示文摘Objective: The aim of our study was to determine an optimal slice thickness that was efficient in revealing bronchial imageology of pulmonary nodules (PNs) on multi-slice spiral computed tomography (MSCT) images preliminarily. Methods: Fifty-four patients with 62 PNs (diameter ≤ 3 cm) underwent multidetector-row computed tomography of the chest in a single-breath-hold technique. The raw data were acquired with a collimation of 0.625 mm. Three sets of contiguous images were reconstructed with 1-, 2-, and 5-mm slice thickness, respectively. Bronchial imageology of SPNs on the CT images presented in 1-, 2-, and 5-mm slice thickness was compared. Using the 1-mm sections as the gold standard, an optimal slice thickness in revealing bronchial imageology of PNs was determined. Results: Bronchial imageology of PNs on the CT images presented in 1 mm slice thickness involved 85 bronchi (35 second-fourth generation bronchi; 50 fifth-eighth generation bronchi). Bronchial imageology on 2-mm-thick sections was as same as that on 1-mm-thick sections in 34 second- fourth generation bronchi. No statistically significant difference in number of second- fourth generation bronchi with same bronchial imageology was found between that on 2-mm-thick images and 1-mm-thick images (P = 0.836 > 0.05). Bronchial imageology on 5-mm-thick sections was as same as that on 1-mm-thick sections in 24 second-fourth generation bronchi. There was statistically significant difference in number of second-fourth generation bronchi with same bronchial imageology between that on 5-mm-thick images and 1-mm-thick images (P = 0.026 < 0.05). Bronchial imageology on 2-mm-thick sections was as same as that on 1-mm-thick sections in 38 fifth-eighth generation bronchi. There was statistically significant difference in number of fifth-eighth generation bronchi with same bronchial imageology between that on 2-mm-thick images and 1-mm-thick images (P = 0.029 < 0.05). Bronchial imageology on 5-mm-thick images was as same as that on 1-mm-thick images in 31 fifth-eighth generation bronchi. There was statistically significant difference in number of fifth-eighth generation bronchi with same bronchial imageology between that on 5-mm-thick sections and 1-mm-thick sections (P = 0.001 < 0.05). Conclusion: It is suggested that the use of 2-mm slice thickness is suitable in revealing second- fourth generation bronchi and the use of 1-mm slice thickness is suitable in revealing fifth-eighth generation bronchi. | Shenjiang Li Changcheng Li Xing Wang Debin Liu Wenjie Liang Feng Zhu Yan Zhu Xuefeng Cui Fangang Hu Yuanyuan Wang | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，11： | 0 |
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