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| 1 | Surface bioactivation of PEEK by neutral atom beam technology显示文摘Polyetheretherketone(PEEK)is an alternative to metallic implants and a material of choice in many applications,including orthopedic,spinal,trauma,and dental.While titanium(Ti)and Ti-alloys are widely used in many intraosseous implants due to its biocompatibility and ability to osseointegrate,negatives include stiffness which contributes to shear stress,radio-opacity,and Ti-sensitivity.Many surgeons prefer to use PEEK due to its biocompatibility,similar elasticity to bone,and radiolucency,however,due to its inert properties,it fails to fully integrate with bone.Accelerated Neutral Atom Beam(ANAB)technology has been successfully employed to demonstrate enhanced bioactivity of PEEK both in vitro and in vivo.In this study,we further characterize surfaces of PEEK modified by ANAB as well as elucidate attachment and genetic effects of dental pulp stem cells(DPSC)exposed to these surfaces.ANAB modification resulted in decreased contact angle at 72.9±4.5°as compared to 92.4±8.5°for control(p<0.01)and a decreased average surface roughness,however with a nano-textured surface profile.ANAB treatment also increased the ability of DPSC attachment and proliferation with considerable genetic differences showing earlier progression towards osteogenic differentiation.This surface modification is achieved without adding a coating or changing the chemical composition of the PEEK material.Taken together,we show that ANAB processing of PEEK surface enhances the bioactivity of implantable medical devices without an additive or a coating. | Joseph Khoury Irina Selezneva Sergei Pestov Vadim Tarassov Artem Ermakov Andrey Mikheev Mikhail Lazov Sean R.Kirkpatrick Dmitry Shashkov Alexandre Smolkov | 2019 | Bioactive Materials2019，4，1： | 2 |
| 2 | Enforcing the Discrete Maximum Principle for Linear Finite Element Solutions of Second-Order Elliptic Problems显示文摘The maximum principle is a basic qualitative property of the solution of second-order elliptic boundary value problems.The preservation of the qualitative characteristics,such as the maximum principle,in discrete model is one of the key requirements.It is well known that standard linear finite element solution does not satisfy maximum principle on general triangular meshes in 2D.In this paper we consider how to enforce discrete maximum principle for linear finite element solutions for the linear second-order self-adjoint elliptic equation.First approach is based on repair technique,which is a posteriori correction of the discrete solution.Second method is based on constrained optimization.Numerical tests that include anisotropic cases demonstrate how our method works for problems for which the standard finite element methods produce numerical solutions that violate the discrete maximum principle. | Richard Liska Mikhail Shashkov | 2008 | Communications in Computational Physics2008，3，4： | 2 |
| 3 | Oxide ceramic coatings on aluminium alloys produced by a pulsed bipolar plasma electrolytic oxidation process显示文摘 | A.L. Yerokhin A. Shatrov V. Samsonov P. Shashkov A. Pilkington A. Leyland A. Matthews | 2005 | Surface & Coatings Technology2005，，2： | 2 |
| 4 | Formulations of artificial viscosity for multi-di- mensional shock wave computations显示文摘 | Caramana E J Shashkov M J Whalen P P | 1998 | Journal of Computational Physics1998，144，1： | 1 |
| 5 | Elimination of artificial grid distortion and hourglass-type mo- tions by means of Lagrangian subzonal masses and pressures显示文摘 | Caramana E J Shashkov M J | 1998 | Journal of Computational Physics1998，142，2： | 1 |
| 6 | Structure of Galactomannans from Gleditsia delavayi and G. aquatica by 1H and 13C NMR Spectroscopy显示文摘 | R. K. Rakhmanberdyeva A. S. Shashkov | 2005 | Chemistry of Natural Compounds2005，，1： | 1 |
| 7 | Isolation and Preliminary Characterization of a Highly Pyruvylated Galactan Sulfate from Codium yezoense (Bryopsidales, Chlorophyta) 显示文摘 | Bilan M B Vinogradova E V Shashkov A S | 2006 | Botaniea Marina2006，49，3： | 1 |
| 8 | Oxide ceramic coatings on aluminium alloys produced by a pulsed bipolar plasma electrolytic oxidation process显示文摘 | YEROKHIN A L SHATROV T A SAMSONOV V SHASHKOV P PILKINGTON A LEYLAND A MATTHEWS A | 2005 | Surf Coat Tech2005，199，23： | 1 |
| 9 | Structure of the 016 polysaccharide from escerichia coli 016: KI: an NMR investigation 显示文摘 | Jann B Alexander S Shashkov | 1994 | Carbohydrate Research1994，264，： | 1 |
| 10 | Full structure of the O-specific polysaccharide of Proteus mirabilis O24 containing 3,4-O--D-galactose显示文摘 | Shashkov A S Senchenkova S N Vinogradov E V | 2000 | Carbohydrate Research2000，329，2： | 1 |
| 11 | Structure of a highly pyruvylated galactan sulfate from the Pacific green alga Codium yezoense (Bryopsidales,Chlorophyta)显示文摘 | Bilan M I Vinogradova E V Shashkov A S | 2007 | Carbohydrate Research2007，342，34： | 1 |
| 12 | Effect of mercury vapors on the oxidation of sulfur dioxide in a fluidized bed of vanadium catalyst 显示文摘 | SHASHKOV V L MUKHLENOV L P BENYASH E Y | 1971 | Khim Prom-st (Moscow)1971，47，： | 1 |
| 13 | Full structure of the O-specific polysaecharide of Proteus mirabilis O24 containing 3,4-0-] (S)-1-carbo xyethylidene] D-galactose显示文摘 | Shashkov A S Senchenkova Sy N Vinogradov E V | 2000 | Carbohydr Res2000，329，2： | 1 |
| 14 | Elimination of artificial grid distortion and hourglass-type motions by means of Lagrangian subzonal masses and pressures显示文摘 | Caramana E J Shashkov M J | 1998 | J Comput Phys1998，142，： | 1 |
| 15 | The internal consistency, stability, and accuracy of the discrete,compatible formulation of Lagrangian hydrodynamics显示文摘 | Bauer A L Burton D E Caramana E J Loubere R Shashkov M J Whalen P P | 2006 | J Comput Phys2006，218，： | 1 |
| 16 | Ustilagic acid secretion by Pseudozyma fusiformata strains显示文摘 | Kulakovskaya T V Shashkov A S Kulakovskaya E V | 2005 | FEMS Yeast Research2005，5，10： | 1 |
| 17 | Antifungal cellobiose lipid secreted by the epiphytic yeast Pseudozyma graminicola 显示文摘 | Golubev W I Kulakovskaya T V Shashkov A S | 2008 | Microbiology2008，77，2： | 1 |
| 18 | Mimetic finite difference methods for diffusion equations on nonorthogonal non-conformal mesh显示文摘 | Lipnikov K Morel J Shashkov M | | 0，，02： | 1 |
| 19 | A local support-operators diffusion discretization scheme for quadrilateral r-z meshes 显示文摘 | Morel J E Roberts R M SHashkov M J | 1998 | Journal of Computational Physics1998，144，： | 1 |
| 20 | Characterization of an antifungal glycolipid secreted by the yeast Sympodiomycopsis paphiopedili 显示文摘 | Kulakovskaya T V Shashkov A S Kulakovskaya E V | 2004 | FEMS Yeast Research2004，5，3： | 1 |
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