|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The importance of exogenous antigen in priming the human CD8+ T cell response:lessons from the EBV nuclear antigen EBNA1显示文摘 | Blake N Haigh T Shaka'a G | 2000 | J Immitnol2000，165，12： | 1 |
| 2 | Squamous cell carcinoma of the stomach显示文摘 | Altshuler JH Shaka JA | 1966 | Cancer1966，19，6： | 1 |
| 3 | Iterative schemes for bilinear operators-application to spin decoupling显示文摘 | Shaka A J Lee C J Pines A | 1988 | J Magn Reson1988，77，： | 1 |
| 4 | The importance of exogenous antigen in priming the human CD8 + T cell Response: lessons from the EBV nuclear antigen EBNAI显示文摘 | Blake N Haigh T Shaka'a G | 2000 | Immunology2000，165，12： | 1 |
| 5 | 显示文摘 | Blake N Haigh T Shaka' a G | 2000 | Immunol2000，165，12： | 1 |
| 6 | A pulsedfield NMR technique without the usual sensitivity loss spatial polulation sculpting显示文摘 | Van Q N Shaka A J | 1996 | J Magn Reson1996，119，： | 1 |
| 7 | Composite pulsed field gradients with refocused chemical shifts and short recovery time显示文摘 | Hu H Shaka A J | 1999 | J Magn Reson1999，136，： | 1 |
| 8 | Chemical conversion of various celluloses to glucose and its derivatives in supercritical water显示文摘 | Shaka S Ueno T | 1999 | Cellulose1999，6，3： | 1 |
| 9 | Application of the filter diagonalization method to one- and two-dimensional NMR spectra 显示文摘 | Mandelshtam V A Taylor H S Shaka A J | 1998 | J Magn Reson1998，133，2： | 1 |
| 10 | Postprocessing and sparse blind source separation of positive and partially overlapped data显示文摘 | Y. Sun C. Ridge F. del Rio A.J. Shaka J. Xin | 2011 | Signal Processing2011，，8： | 1 |
| 11 | Chemical conversion of various celluloses to glu- cose and its derivatives in supercritical water显示文摘 | Shaka S Ueno T | 1999 | Cellulose1999，6，3： | 1 |
| 12 | Chemical conversion of various celluloses to glucose and its derivatives in supercritical water显示文摘 | Shaka S Ueno T | 1999 | Cellulose1999，6，3： | 1 |
| 13 | Readmission rates and outcomes in adults with and without COVID-19 following inpatient chemotherapy admission:A nationwide analysis显示文摘BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has received considerable attention in the scientific community due to its impact on healthcare systems and various diseases.However,little focus has been given to its effect on cancer treatment.AIM To determine the effect of COVID-19 pandemic on cancer patients’care.METHODS A retrospective review of a Nationwide Readmission Database(NRD)was conducted to analyze hospitalization patterns of patients receiving inpatient chemotherapy(IPCT)during the COVID-19 pandemic in 2020.Two cohorts were defined based on readmission within 30 d and 90 d.Demographic information,readmission rates,hospital-specific variables,length of hospital stay(LOS),and treatment costs were analyzed.Comorbidities were assessed using the Elixhauser comorbidity index.Multivariate Cox regression analysis was performed to identify independent predictors of readmission.Statistical analysis was conducted using Stata■Version 16 software.As the NRD data is anonymous and cannot be used to identify patients,institutional review board approval was not required for this study.RESULTS A total of 87755 hospitalizations for IPCT were identified during the pandemic.Among the 30-day index admission cohort,55005 patients were included,with 32903 readmissions observed,resulting in a readmission rate of 59.8%.For the 90-day index admission cohort,33142 patients were included,with 24503 readmissions observed,leading to a readmission rate of 73.93%.The most common causes of readmission included encounters with chemotherapy(66.7%),neutropenia(4.36%),and sepsis(3.3%).Comorbidities were significantly higher among readmitted hospitalizations compared to index hospitalizations in both readmission cohorts.The total cost of readmission for both cohorts amounted to 1193000000.00 dollars.Major predictors of 30-day readmission included peripheral vascular disorders[Hazard ratio(HR)=1.09,P<0.05],paralysis(HR=1.26,P<0.001),and human immunodeficiency virus/acquired immuno-deficiency syndrome(HR=1.14,P=0.03).Predictors of 90-day readmission included lymphoma(HR=1.14,P<0.01),paralysis(HR=1.21,P=0.02),and peripheral vascular disorders(HR=1.15,P<0.01).CONCLUSION The COVID-19 pandemic has significantly impacted the management of patients undergoing IPCT.These findings highlight the urgent need for a more strategic approach to the care of patients receiving IPCT during pandemics. | Philip Kanemo Keffi Mubarak Musa Vaishali Deenadayalan Rafaella Litvin Olubunmi Emmanuel Odeyemi Abdultawab Shaka Naveen Baskaran Hafeez Shaka | 2023 | World Journal of Clinical Oncology2023，14，8： | 0 |
| 14 | Trends of alcoholic liver cirrhosis readmissions from 2010 to 2018:Rates and healthcare burden associated with readmissions显示文摘BACKGROUND Alcoholic liver cirrhosis(ALC)is a chronic liver disease with varying disease severity.Readmissions of ALC are associated with poor outcomes.AIM To identify and assess trends of readmissions for ALC over an eight-year period.METHODS This retrospective interrupted trend study analysed 30-d readmissions of ALC in the United States from 2010 to 2018 using the National Readmissions Database.Hospitalization for ALC was the reason for index admission obtained using the International Classification of Diseases codes(571.2 and K70.3X).Biodemographic characteristics and hospitalization trends were highlighted over time.A multivariate regression analysis model was used to calculate the trend for riskadjusted odds of 30-d all-cause ALC readmissions,ALC specific readmission rate,ALC readmission proportion,inpatient mortality,mean length of stay(LOS)and mean total hospital cost(THC)following adjustments for age,gender,grouped Charlson Comorbidity Index,insurance,mean household income,and hospital characteristics.RESULTS There was a trend towards increasing total 30-d readmissions of ALC from 7660 in 2010 to 15085 in 2018(P<0.001).Patients readmitted for ALC were noted to have an increasing comorbidity burden over time.We noted a rise in the risk-adjusted 30-d all-cause readmission of ALC from 24.9%in 2010 to 29.9%in 2018(P<0.001).ALC-specific readmission rate increased from 6.3%in 2010 to 8.4%in 2018(P<0.001)while ALC readmission proportion increased from 31.4%in 2010 to 36.3%in 2018(P<0.001).Inpatient mortality for 30-d readmissions of ALC declined from 10.5%in 2010 to 8.2%in 2018(P=0.0079).However,there was a trend towards increasing LOS from 5.6 d in 2010 to 6.3 d in 2018(P<0.001)and increasing THC from 13790 dollars in 2010 to 17150 dollars in 2018(P<0.001).The total days of hospital stay attributable to 30-d readmissions of ALC increased by 119.2%while the total attributable hospital costs increased by 149%by the end of 2018.CONCLUSION There was an increase in the 30-d readmission rate and comorbidity burden for ALC;however,inpatient mortality declined.Additionally,there was a trend towards increasing LOS and THC for these readmissions. | Asim Kichloo Zain El-Amir Dushyant Singh Dahiya Farah Wani Jagmeet Singh Dhanshree Solanki Ehizogie Edigin Precious Eseaton Asad Mehboob Hafeez Shaka | 2021 | World Journal of Hepatology2021，13，12： | 0 |
| 15 | Increasing thirty-day readmissions of Crohn’s disease and ulcerative colitis in the United States:A national dilemma显示文摘BACKGROUND The prevalence of Crohn’s disease(CD)and ulcerative colitis(UC)is on the rise worldwide.This rising prevalence is concerning as patients with CD and UC may frequently relapse leading to recurrent hospitalizations and increased healthcare utilization.AIM To identify trends and adverse outcomes for 30 d readmissions for CD and UC.METHODS This was a retrospective,interrupted trends study involving all adult(≥18 years)30 d readmissions of CD and UC from the National Readmission Database(NRD)between 2008 and 2018.Patients<18 years,elective,and traumatic hospitalizations were excluded from this study.We identified hospitalization characteristics and readmission rates for each calendar year.Trends of inpatient mortality,mean length of hospital stay(LOS)and mean total hospital cost(THC)were calculated using a multivariate logistic trend analysis adjusting for age,gender,insurance status,comorbidity burden and hospital factors.Furthermore,trends between CD and UC readmissions were compared using regression of the interaction coefficient after adjusting for age and gender to determine relative trends between the two populations.Stata®Version 16 software(StataCorp,TX,United States)was used for statistical analysis and P value≤0.05 were considered statistically significant.RESULTS Total number of 30 d readmissions increased from 6202 in 2010 to 7672 in 2018 for CD and from 3272 in 2010 to 4234 in 2018 for UC.We noted increasing trends for 30-day all-cause readmission rate of CD from 14.9%in 2010 to 17.6%in 2018(P-trend<0.001),CD specific readmission rate from 7.1%in 2010 to 8.2%in 2018(P-trend<0.001),30-day all-cause readmission rate of UC from 14.1%in 2010 to 15.7%in 2018(P-trend=0.003),and UC specific readmission rate from 5.2%in 2010 to 5.6%in 2018(P-trend=0.029).There was no change in the risk adjusted trends of inpatient mortality and mean LOS for CD and UC readmissions.However,we found an increasing trend of mean THC for UC readmissions.After comparison,there was no statistical difference in the trends for 30 d all-cause readmission rate,inpatient mortality,and mean LOS between CD and UC readmissions.CONCLUSION There was an increase in total number of 30 d readmissions for CD and UC with a trend towards increasing 30 d all-cause readmission rates. | Dushyant Singh Dahiya Abhilash Perisetti Asim Kichloo Amandeep Singh Hemant Goyal Laura Rotundo Madhu Vennikandam Hafeez Shaka Gurdeep Singh Jagmeet Singh Sailaja Pisipati Mohammad Al-Haddad Madhusudhan R Sanaka Sumant Inamdar | 2022 | World Journal of Gastrointestinal Pathophysiology2022，13，3： | 0 |
| 16 | THE EVOLUTION OF TIBETAN CIVILIAN DWELLING DECORATIONS显示文摘Today,the displayed contents and decorations showing in civilian dwellings of ethnic Tibetans has surpassed far away from the original and traditional appearance.No more are they caged in fixed and rigid traditional stone and wood structures with white walls. | Shaka Wangdu | 2019 | China's Tibet2019，30，1： | 0 |
| 17 | Co-pyrolysis of South African bituminous coal and Scenedesmus microalgae:Kinetics and synergistic effects study显示文摘In this work,the co-pyrolysis of coal and algae is explored with special emphasis on decomposition kinetics and the possibility of the existence of synergistic effects.Modelling and kinetics analysis based approaches were used for the investigation of the existence of synergistic effects.The co-pyrolysis kinetics was studied using the model-free,Coats-Redfern integral method.The kinetics were evaluated for 1st and 2nd order reaction models.Results reveal that Scenedesmus microalgae is characterised by a two stage decomposition process that occurs at temperature ranges of 200-400℃and 500-700℃with activation energy of 145.5 and 127.3 kJ/mol,respectively.Bituminous coal has a two stage,slow decomposition process that occurs at temperature ranges of 400-700℃and above 750℃with an activation energy of 81.8 and 649.3 kJ/mol,respectively.Furthermore,co-pyrolysis of coal and microalgae is characterised by three stages whose kinetics are dominated by the pyrolysis of the individual materials.For the studied range of coal/algae ratios,the three pyrolysis stages occur in the approximate temperature ranges of 200-400℃,430-650℃and above 750℃,with activation energies in the ranges of 131-138,72-78 and 864.5-1235 kJ/mol,respectively.Modelling and kinetics study showed that there is strong evidence of interactions between coal and microalgae that manifest as synergistic effects especially in the second and third stages of decomposition. | Bothwell Nyoni Sifundo Duma Lukanyo Bolo Shaka Shabangu Shanganyane F.Hlangothi | 2020 | International Journal of Coal Science & Technology2020，7，4： | 0 |
| 18 | Systemic adverse effects and toxicities associated with immunotherapy:A review显示文摘Immunotherapy is rapidly evolving secondary to the advent of newer immunotherapeutic agents and increasing approval of the current agents by the United States Food and Drug Administration to treat a wide spectrum of cancers.Immunotherapeutic agents have gained immense popularity due to their tumorspecific action.Immunotherapy is slowly transforming into a separate therapeutic entity,and the fifth pillar of management for cancers alongside surgery,radiotherapy,chemotherapy,and targeted therapy.However,like any therapeutic entity it has its own adverse effects.With the increasing use of immunotherapeutic agents,it is vital for physicians to acquaint themselves with these adverse effects.The aim of this review is to investigate the common systemic adverse effects and toxicities associated with the use of different classes of immunotherapeutic agents.We provide an overview of potential adverse effects and toxicities associated with different classes of immunotherapeutic agents organized by organ systems,as well as an extensive discussion of the current recommendations for treatment and clinical trial data.As we continue to see increasing usage of these agents in clinical practice,it is vital for physicians to familiarize themselves with these effects. | Asim Kichloo Michael Albosta Dushyant Dahiya Jean Claude Guidi Michael Aljadah Jagmeet Singh Hafeez Shaka Farah Wani Akshay Kumar Manidhar Lekkala | 2021 | World Journal of Clinical Oncology2021，12，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员