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| 1 | Presence of Porphyromonas gingivalis in gingival squamous cell carcinoma显示文摘Periodontal disease has been recently linked to a variety of systemic conditions such as diabetes, cardio-vascular disease, preterm delivery, and oral cancer. The most common bacteria associated with periodontal disease, Porphyromonas gingivalis (P. gingivalis) has not yet been studied in the malignant gingival tissues. The objective of this study was to investigate the presence of P. gingivalis in specimens from squamous cell carcinoma patients. We have performed immunohistochemical staining to investigate the presence of P. gingivalis and Streptococcus gordonii (S. gordonii), a non invasive oral bacteria, in paraffin embedded samples of gingival squamous cell carcinoma (n=10) and normal gingiva (n=5). Staining for P. gingivalis revealed the presence of the bacteria in normal gingival tissues and gingival carcinoma, with higher levels (more than 33%, P<0.05) detected in the carcinoma samples. The staining intensity was also significantly enhanced in the malignant tissue by 2 folds (P<0.023) compared to specimens stained for the non-invasive S. gordonii. P. gingivalis is abundantly present in malignant oral epithelium suggesting a potential association of the bacteria with gingival squamous cell carcinoma. | Joseph Katz Mairelys D. Onate Kaleb M. Pauley Indraneel Bhattacharyya Seunghee Cha | 2011 | International Journal of Oral Science2011，3，4： | 19 |
| 2 | Two gap-free reference genomes and a global view of the centromere architecture in rice显示文摘Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ago.However,reference genomes for all higher organisms to date contain gaps and missing sequences.Here,we report the assembly and analysis of gap-free reference genome sequences for two elite O.sativa xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and yield.Gap-free reference genomes provide the opportunity for a global view of the structure and function of centromeres.We show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and structures.In addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and homogenization.Both genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively transcribed.Two large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two genomes.The availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties. | Jia-Ming Song Wen-Zhao Xie Shuo Wang Yi-Xiong Guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng Huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou Xi-Tong Zhu Daojun Yuan Joshua Udall Weibo Xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang Ling-Ling Chen | 2021 | Molecular Plant2021，14，10： | 9 |
| 3 | Optimal Control of a Mackerel-Mimicking Robot for Energy Efficient Trajectory Tracking显示文摘A robotic fish, BASEMACK1, is designed and fabricated by mimicking the shape of a live mackerel. Three DC servo-motors are serially linked together and actuated to mimic the mackerel's Carangiform motion. Hydrodynamic charac- teristics of a fish-mimetic test model are experimentally identified and utilized in order to numerically simulate fish swimming. The discrete set of kinematic and dynamic parameters are obtained by considering required horizontal and lateral forces and minimum energy consumption. Using the optimized parameter set, optimal control of the robot is studied. | Seunghee Lee Jounghyun Park Cheolheui Han | 2007 | Journal of Bionic Engineering2007，4，4： | 6 |
| 4 | Akt is negatively regulated by the MULAN E3 ligase显示文摘serine/threonine kinase Akt 在多重细胞的进程工作,包括房间幸存和肿瘤开发。否定地调整 Akt 的机制的研究集中了于调停 dephosphorylation 的 inactivation。在这研究,我们识别了 Akt 的一个否定管理者, MULAN,它拥有一个戒指手指领域和 E3 ubiquitin ligase 活动。Akt 被发现直接与 MULAN 交往并且是由在 vitro 并且在 vivo 的 MULAN 的 ubiquitinated。另外的分子的试金证明 phosphorylated Akt 由 MULAN 是为和 MULAN 和 ubiquitination 的相互作用的一个真实目标。功能的研究的结果建议由 MULAN 的 Akt 的降级压制房间增长和生存能力。这些数据提供卓见进 Akt ubiquitination 发信号网络。 | Seunghee Bae Sun-Yong Kim Jin Hyuk Jung Yeongmin Yoon Hwa Jun Cha Hyunjin Lee Karam Kim Jongran Kim In-Sook An Jongdoo Kim Hong-Duck Um In-Chul Park Su-Jae Lee Seon Young Nam Young-Woo Jin Jae Ho Lee Sungkwan An | 2012 | Cell Research2012，22，5： | 3 |
| 5 | 相区成像——电磁波场中的等效地震偏移算法显示文摘电磁资料的另一种解释方法是将观测数据下延,以构制产生这些数据的地下二维电阻率介质模型。将电磁波波动方程与声波动方程类比可知,下延可以用一直接法进行。运用适当的近似算法,取等效方程式中相同的主要项,並将初值问题化为边值问题,则电磁资料的成像可用由地震资料偏移技术导出的任何方法去完成。我们这里选用的是Claerbout单程有限差分波动方程偏移技术。计算是在频率域中进行的。分别处理电场和磁场视剖面,以获得这两个关联反射的像。实际反射位置的最佳估计是这两个像相吻合的地方。反过来,可用同样的方法去模拟二维电阻率分布的响应。方法中的主要假设与现代地震资料处理中的假设基本类似:即数据波场中所含的电磁反射的细节可与背景电导率(波场在背景电导率分布中进行下延)分布相分离,且无多次反射。由此可知,其主要约束为电阻率的变化足够小。成像结果表明,电阻率(是位置的函数)成像的想法是切实可行的,而且可直接模仿地震偏移技术。 | Seunghee Lee George A. McMechan Carlos L. V. Aiken 曹辉 | 1989 | 石油物探译丛1989，，1： | 3 |
| 6 | A Mandatory Uniform Policy in Urban Schools: Findings from the School Survey on Crime and Safety: 2003-04 显示文摘 | Seunghee Hart | 2010 | International Journal of Education Policy and Leadership2010，5，8： | 1 |
| 7 | Nitrate reduction by zero-valent iron under different pH regimes显示文摘 | Seunghee Choea Howard M Liljestrand | 2004 | Applied Geo- chemistry2004，19，： | 1 |
| 8 | A rat model for radiation-induced proctitis显示文摘 | Seunghee Kang Mison Chun | 2000 | J Korean Med Sci2000，15，： | 1 |
| 9 | Kinetics of ReductiveDenitrification by Nanoscale Zero Valent iron显示文摘 | Seunghee Choe | 2000 | Chemosphere2000，41，： | 1 |
| 10 | Effect of thermal treatment on the aluminum hydroxide nanofibers synthesized by electrolysis of A1 plates显示文摘 | Seunghee Woo Joong-Hark Park Chang Kyu Rhee | 2012 | Mieroeleetronie Engineering2012，，89： | 1 |
| 11 | Kinet- ics of reductive dentrification by nanosecale zerovalent iron显示文摘 | Seunghee Choe Yoon-Young Chang Kyung-Yub Hwang | 2000 | Chemo- sphere2000，41，： | 1 |
| 12 | Synthesis of a graphene-carbon nanotube composite and its electrochemi- cal sensing of hydrogen peroxide 显示文摘 | Seunghee W Yang-Rae K Taek D C | 2012 | Electrochimica Ac- ta2012，59，： | 1 |
| 13 | A rat model for radiation - induced proctitis显示文摘 | Seunghee Kang Mison Chun Yoon - Mi Jin | 2000 | J Korean Med Sci2000，15，： | 1 |
| 14 | Nitrate reduction by zero-valent iron under different pH regimes显示文摘 | Seunghee Choe Howard M Liljestrand Jeehyeong Khim | 2004 | Applied Geochemistry2004，19，3： | 1 |
| 15 | Kinetics of reductive dentrification by nanoscale zerovalent iron 显示文摘 | Seunghee Choe Yoon - Young Chang Kyung - Yub Hwang | 2000 | Chemosphere2000，41，： | 1 |
| 16 | Shift scheduling for steppers in the semiconductor wafer fabrication process 显示文摘 | SOOYOUNG K SEUNGHEE Y BOKANG K | 2002 | ⅡE Transactions2002，34，3： | 1 |
| 17 | Improvement of adhesion properties for Cu films on the polyimide by plasma source ion implantation显示文摘 | Ju Hi Hong Yeonhee Lee Seunghee Han | 2006 | Surface : Coatings Technology2006，201，： | 1 |
| 18 | Impedance-based wireless debonding condition monitoring of CFRP laminated concrete structures显示文摘 | SEUNGHEE P KIM J W CHANGGIL L | 2011 | NDT&E International2011，44，： | 1 |
| 19 | The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions显示文摘 | Seunghee Yoon Rony Seger | 2006 | Growth Factors2006，，1： | 1 |
| 20 | An integrated material re- moval model for silicon dioxide layers in chemical me- chanical polishing processes 显示文摘 | Seunghee Oh Jongwon Seok | 2009 | Wear2009，266，： | 1 |
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