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| 1 | Intestinal microbiota and immunoglobulin E responses in 5-year-old Estonian children 显示文摘 | Sepp E Julge K Mikelsaar M | 2005 | Clin Exp Allergy2005，35，： | 1 |
| 2 | Effect of catalyst and polymerization conditions on the preparation of low molecular weight lactic acid polymers显示文摘 | Hiltunen K Seppǎlǎ J V Hǎrkǎnen M | 1997 | Macromolecules1997，30，： | 1 |
| 3 | Metabolomic changes in fatty liver can be modified by dietary protein and calcium during energy restriction显示文摘AIM: To characterise the effect of energy restriction (ER) on liver lipid and primary metabolite profile by using metabolomic approach. We also investigated whether the effect of energy restriction can be further enhanced by modif ication of dietary protein source and calcium. METHODS: Liver metabolomic profile of lean and obese C57Bl/6J mice (n = 10/group) were compared with two groups of weight-reduced mice. ER was performed on control diet and whey protein-based high-calcium diet (whey + Ca). The metabolomicanalyses were performed using the UPLC/MS based lipidomic platform and the HPLC/MS/MS based primary metabolite platform. RESULTS: ER on both diets significantly reduced hepatic lipid accumulation and lipid droplet size, while only whey + Ca diet significantly decreased blood glucose (P < 0.001) and serum insulin (P < 0.01). In hepatic lipid species the biggest reduction was in the level of triacylglycerols and ceramides while the level of cholesterol esters was significantly increased during ER. Interestingly, diacylglycerol to phospholipid ratio, an indicator of relative amount of diabetogenic diglyceride species, was increased in the control ER group, but decreased in the whey + Ca ER group (P < 0.001, vs obese). ER on whey + Ca diet also totally reversed the obesity induced increase in the relative level of lipotoxic ceramides (P < 0.001, vs obese; P > 0.05, vs lean). These changes were accompanied with up-regulated TCA cycle and pentose phosphate pathway metabolites. CONCLUSION: ER-induced changes on hepatic metabolomic profile can be significantly affected by dietary protein source. The therapeutic potential of whey protein and calcium should be further studied. | Taru K Pilvi Tuulikki Seppnen-Laakso Helena Simolin Piet Finckenberg Anne Huotari Karl-Heinz Herzig Riitta Korpela Matej Orei Eero M Mervaala | 2008 | World Journal of Gastroenterology2008，14，28： | 1 |
| 4 | Successful treatment of recalcitrant relapsing polychondritis with monoclonal antibodies显示文摘 | Ratzinger G Kuen-Spiegl M Sepp N | 2009 | J Eur Acad Dermatol Venereol2009，23，4： | 1 |
| 5 | Immunohistochemical demonstration of carbonic anhydrase isoenzyme VI (CA VI) expression in rat lower airways and lung显示文摘 | LEINONEN J S SAARI K A SEPP(A)NEN J M | 2004 | J Histochem Cytochem2004，52，8： | 1 |
| 6 | Rock pingos in northern Ungava Peninsula,Quebec,Canada显示文摘 | Sepp?l? M | 1988 | Canadian Journal of Earth Sciences1988，25，4： | 1 |
| 7 | Recent primary Toxoplama infection indicated by a low avidity of specific IgG显示文摘 | Hedman K Lappalainen M Sepp(a)i(a) I | 1989 | J Infect Dis1989，159，4： | 1 |
| 8 | Intestinal microflora of Estonian and Swedish infants显示文摘 | Sepp E Julge V Vasar M | 1997 | Acta Paediatr1997，86，9： | 1 |
| 9 | NF-kappaB-de- pendent regulation of brain-derived neurotrophic factor in hip- pocampal neurons by X-linked inhibitor of apoptosis protein 显示文摘 | Kairisalo M Korhonen L Sepp M | 2009 | Eur J Neurosci2009，30，6： | 1 |
| 10 | Measurements and descriptions of underwater noise in Finland显示文摘 | Sepp(a)nen J Nieminen M | | 0，，1： | 1 |
| 11 | Intestinal microflora of Estonian and Swedish infants显示文摘 | Sepp E Julge K Vasar M | 1997 | Acta Paediatr1997，86，9： | 1 |
| 12 | Intestinal microflora of Estonian and Swedish infants显示文摘 | Sepp E Julge K Vasar M | 1997 | Acta Paediatr1997，6，9： | 1 |
| 13 | The comparison of susceptibility patterns of Gram-negativeinvasive and non-invasive pathogens in Estonian hospitals显示文摘 | Loivukene K Kermes K Sepp E Adamson V Mitt P Jurna M | 2006 | An-tonie Van Leeuwenhoek2006，89，34： | 1 |
| 14 | External Silane Donorsin Ziegler-Natta Catalysis:A Three-Site Model Analysis ofEffects on Catalyst Active Sites显示文摘 | H rk nen M Sepp l J Salminen H | 1995 | Polym J1995，27，3： | 1 |
| 15 | Transformation of LPG into aromatic hydrocarbons and hydrogen over zeolite catalysts显示文摘 | GIU SEPPE G RE INALDO M ROBERTO G | 1994 | Catal Rev Sci Eng1994，36，2： | 1 |
| 16 | Simultaneous determination of fluoroquinolones,sulfonamides andtetracyclines in sewage sludge by pressurized liquid extraction and liquid chromatography electrospray ionization-masss pectrometry显示文摘 | LILLENBERG M YURCHENKOS KIPPER K HERODES K PIHLV SEPP K LHMU R NEI L | 2009 | J Chromatogr:A2009，1216，32： | 1 |
| 17 | External Alkox-ysilane Donors in Ziegler-Natta Catalysis:Effects onPoly(Propylene)Microstructure显示文摘 | H rk nen M Sepp l J V V n nen T | 1991 | Macromol Chem Phys1991，192，3： | 1 |
| 18 | Up to 10 years fol ow up of the use of 71 cortical al ografts (strut-grafts) for the treatment of periprosthetic fractures显示文摘 | Virolainen P Mokka J Sepp?nen M | | 0，，04： | 1 |
| 19 | Why,when and how do HVAC-systems pollute the indoor environment and what to do about it? The European AIRLESS Project显示文摘 | Bluyssen P M Cox C Seppnen O | 2003 | Building Environ2003，38，： | 1 |
| 20 | Miero RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells 显示文摘 | Shi B Sepp Lorenzino L Prisco M | 2007 | J Biol Chem2007，282，32： | 1 |
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