维普中文期刊产品整合服务
1篇 您的检索式:作者名="Seonghun Im"
    题名 作者 年代 出处 被引量
1Propagating acoustic waves on a culture substrate regulate the directional collective cell migration显示文摘Collective cell migration plays a critical role in physiological and pathological processes such as development,wound healing,and metastasis.Numerous studies have demonstrated how various types of chemical,mechanical,and electrical cues dictate the collective migratory behaviors of cells.Although an acoustic cue can be advantageous because of its noninvasiveness and biocompatibility,cell migration in response to acoustic stimulation remains poorly understood.In this study,we developed a device that is able to apply surface acoustic waves to a cell culture substrate and investigated the effect of propagating acoustic waves on collective cell migration.The migration distance estimated at various wave intensities revealed that unidirectional cell migration was enhanced at a critical wave intensity and that it was suppressed as the intensity was further increased.The increased migration might be attributable to cell orientation alignment along the direction of the propagating wave,as characterized by nucleus shape.Thicker actin bundles indicative of a high traction force were observed in cells subjected to propagating acoustic waves at the critical intensity.Our device and technique can be useful for regulating cellular functions associated with cell migration.Chikahiro Imashiro Byungjun Kang Yunam Lee Youn-Hoo Hwang Seonghun Im Dae-Eun Kim Kenjiro Takemura Hyungsuk Lee 2021Microsystems & Nanoengineering2021,7,6:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费