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| 1 | Beta-blocker therapy in elderly patients with renal dysfunction and heart failure显示文摘OBJECTIVE To assess the role of beta-blockers(BB)in patients with chronic kidney disease(CKD)aged≥75 years.METHODS AND RESULTS From January 2008 to July 2014,we included 390 consecutive patients≥75 years of age with ejection fraction≤35%and glomerular filtration rate(GFR)≤60 m L/min per 1.73 m^2.We analyzed the relationship between treatment with BB and mortality or cardiovascular events.The mean age of our population was 82.6±4.1 years.Mean ejection fraction was 27.9%±6.5%.GFR was 60-45 m L/min per 1.73 m^2 in 50.3%of patients,45-30 m L/min per 1.73 m^2 in 37.4%,and<30 m L/min per 1.73 m^2 in 12.3%.At the conclusion of follow-up,67.4%of patients were receiving BB.The median follow-up was28.04(IR:19.41-36.67)months.During the study period,211 patients(54.1%)died and 257(65.9%)had a major cardiovascular event(death or hospitalization for heart failure).BB use was significantly associated with a reduced risk of death(HR=0.51,95%CI:0.35-0.74;P<0.001).Patients receiving BB consistently showed a reduced risk of death across the different stages of CKD:stage IIIa(GFR=30-45 m L/min per 1.73 m^2;HR=0.47,95%CI:0.26-0.86,P<0.0001),stage IIIb(GFR 30-45 m L/min per 1.73 m^2;HR=0.55,95%CI:0.26-1.06,P=0.007),and stages IV and V(GFR<30 m L/min per 1.73 m~2;HR=0.29,95%CI:0.11-0.76;P=0.047).CONCLUSIONS The use of BB in elderly patients with HFr EF and renal impairment was associated with a better prognosis.Use of BB should be encouraged when possible. | Juan Martínez-Milla Marcelino Cortés García Julia Anna Palfy Mikel Taibo Urquía Marta López Castillo Ana Devesa Arbiol Ana Lucía Rivero Monteagudo María Luisa Martín Mariscal Inés Jiménez-Varas Sem Briongos Figuero Juan Antonio Franco-Pelaéz JoséTuñón | 2021 | Journal of Geriatric Cardiology2021，18，1： | 3 |
| 2 | Total hip arthroplasty for femoral neck fracture : comparing in - hospital mortality, complications, and disposi- tion to an elective patient population显示文摘 | Sassoon A D?tpuzzo M Sems S | 2013 | J Arthroplast2013，28，9： | 1 |
| 3 | 显示文摘 | Tesfaye S Chaturvedi N Eaton SEM | 2005 | N Engl J Med2005，352，： | 1 |
| 4 | Imaging features of CNS tu- berculosis显示文摘 | Sem lali S EI Kharras A Mahi M | 2008 | J Radiaol2008，89，： | 1 |
| 5 | By- products from herbs essential oil production as ingredient in marinade for turkey thighs 显示文摘 | Mielnik M B Sem S Egelandsdal B | 2008 | LWT- Food Science and Technology2008，41，1： | 1 |
| 6 | Continuous llending Approach in the Manufacture of Epoxidized ~oybean Plasticized Poly ( lactic Acid) Sheets and Films 显示文摘 | Vijayarajan S Selke SEM Matuana LM | 2014 | Mareomol Mater Eng2014，299，： | 1 |
| 7 | Structural characterization and optimization of antibody-selected phage library mimotopes of an antigen associated with autoimmune recurrent thrombosis 显示文摘 | Sem D S Baker B L Victoria E J | 1998 | Biochemistry1998，37，16： | 1 |
| 8 | Concomitant chemotherapy and radiation for the treatment of advanced-stage endometrial cancer 显示文摘 | WILKINSON-RYAN I BINDER P S POURABOLGHA- SEM S | 2014 | Gynecol Oncol2014，134，1： | 1 |
| 9 | By-products fromherbs essential oil production as ingredient in marinade for turkeythighs显示文摘 | MIELNIK M B SEM S EGELANDSDAL B | 2008 | LWT-Food Science and Technology2008，41，： | 1 |
| 10 | Total hip arthroplasty for femoral neck fracture:comparing in-hospital mortality,complications,and disposition to an elective patient population显示文摘 | Sassoon A D'Apuzzo M Sems S | | J Arthroplasty0，28，9： | 1 |
| 11 | The prevalence and in cidence ofpres sure ulcers in hospitalized pat ient sin the Neth erlands:A prospect ire incept ion coh or t study 显示文摘 | Schoon hoven L Bou sem a MT Bus ken s E | 2007 | Int J Nu rsStud2007，44，6： | 1 |
| 12 | Total hip arthro-plasty for femoral neck fracture: Comparing in - hospitalmortality?complications, and disposition to an elective pa-tient population显示文摘 | SassoonA’D'Apuzzo M Sems S^et a/ | 2013 | J Arthroplasty2013，28，9： | 1 |
| 13 | Results of polyaxial locked-plate fixation of periarticular fractures of the knee 显示文摘 | Haidukewyeh G Sems S A Huebner D | 2007 | J Bone Joint Surg Am2007，89，3： | 1 |
| 14 | Total hip arthroplas- ty for femoral neck fracture: Comparing in-hospital mor-tality,complications,and disposition to an elective patient population显示文摘 | Sassoon A D/Apuzzo M Sems S | 2013 | The Journal of Arthroplasty2013，28，9： | 1 |
| 15 | Effect of albumin concentration and serum matrix on ischemia-modified albumin显示文摘 | Hakligr A K(o)sem A Sene(s) M | 2010 | Clin Biochem2010，43，3： | 1 |
| 16 | Total hip arthroplasty for femoral neck fracture:comparing in-hospital mortality,complications,and disposition to an elective patient population显示文摘 | Sassoon A D'Apuzzo M Sems S | 2013 | J Arthroplasty2013，28，9： | 1 |
| 17 | Congruence of molecular, morphological, and biochemical profiles in Rutaceae: a cladistic analysis of the subfamilies rutoideae and tod- dalioideae 显示文摘 | Sem P W Chui S P Simmons M P | 2007 | Syst Bot2007，32，4： | 1 |
| 18 | The thyroid scan in Hashimoto's thyroiditis:the great mimic显示文摘 | Ramtoola S Maisey MN Clark SEM | 1988 | Nucl Med Commun1988，9，9： | 1 |
| 19 | Total hip arthroplasty for femoral neck fracture : comparing in-hos显示文摘 | Sassoon A D'Apuzzo M Sems S | 2013 | J Arthroplast2013，28，9： | 1 |
| 20 | Chemical vaporinfiltration method for deposition of gold nanoparticles on porous alumina supports显示文摘 | Sem Yannikov P Moroz B L Trubin S | 2006 | Journal of Structural Chemistry2006，47，3： | 1 |
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