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| 1 | RhoA as a target to promote neuronal survival and axon regeneration显示文摘Paralysis following spinal cord injury(SCI) is due to failure of axonal regeneration. It is believed that the capacities of neurons to regrow their axons are due partly to their intrinsic characteristics, which in turn are greatly influenced by several types of inhibitory molecules that are present, or even increased in the extracellular environment of the injured spinal cord. Many of these inhibitory molecules have been studied extensively in recent years. It has been suggested that the small GTPase Rho A is an intracellular convergence point for signaling by these extracellular inhibitory molecules, but due to the complexity of the central nervous system(CNS) in mammals, and the limitation of pharmacological tools, the specific roles of Rho A are unclear. By exploiting the anatomical and technical advantages of the lamprey CNS, we recently demonstrated that Rho A knockdown promotes true axon regeneration through the lesion site after SCI. In addition, we found that Rho A knockdown protects the large, identified reticulospinal neurons from apoptosis after their axons were axotomized in spinal cord. Therefore, manipulation of the Rho A signaling pathway may be an important approach in the development of treatments that are both neuroprotective and axon regeneration-promoting, to enhance functional recovery after SCI. | Jianli Hu Michael E. Seizer | 2017 | Neural Regeneration Research2017，12，4： | 4 |
| 2 | Volume-to-creatinine clearance ra- tio显示文摘 | Laskey WK Jenkins C Seizer F | 2007 | J Am Coil Cardiol2007，50，： | 1 |
| 3 | Interaction of platelets and inflammatory endothelium in the development and progres- sion of coronary artery disease显示文摘 | Langer HF Bigalke B Seizer P | 2010 | Semin Thromb Hemost2010，36，2： | 1 |
| 4 | Comparison of inhospital and one-year outcomes in patients with and without diabetes mellitus undergoing percutaneous catheter intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry) 显示文摘 | Laskey W K Seizer F Vlachos H A | 2002 | Am J Cardiol2002，90，10： | 1 |
| 5 | Platelet-monocyte interactions-a dangerous liaison linking thrombosis, inflammation and athero-sclerosis显示文摘 | Seizer P Gawaz M May AE | 2008 | Curr Med Chem2008，15，20： | 1 |
| 6 | EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation 显示文摘 | Seizer P Schnberger T Schitt M | 2010 | Atherosclerosis2010，209，： | 1 |
| 7 | Serum VEGF levels in patients undergoing primary radiotherapy for cervical cancer:impact on progression-free survival显示文摘 | Bachtiary B Seizer E Knocke T H | | 0，，02： | 1 |
| 8 | EMMPRIN and its ligand cyclophilin A regulate MT1-MMP,MMP-9 and M-CSF during foam cell formation显示文摘 | Seizer P Schonberger T Schott M | | 0，，01： | 1 |
| 9 | Platelets in inflammation and atherogenesis 显示文摘 | Nording HM Seizer P Langer HF | 2015 | Front Immunol2015，6，3： | 1 |
| 10 | Platelet aggregates- genitor cell proliferation and and foam cells is mediated by in vitro 显示文摘 | Stellos K Seizer P Bigalke induced human CD34 + pro different stromal Hemost iation to macrophages cell derived factor 1 B | 2010 | Semin Thromb2010，36，2： | 1 |
| 11 | EMMPRIN and its ligand cyclophilin A regulateMT1-MMP,MMP-9 and MCSF during foam cell formation显示文摘 | Seizer P Schonberger T Schott M | 2010 | Atherosclerosis2010，209，1： | 1 |
| 12 | Bladder tumor markers for monitoring recurrence and screening comparison of hyaluronic acid - hyaluronidase and BTA - Stat tests 显示文摘 | Lokeshwar VB Schroeder GL Seizer MG | 2002 | Cancer2002，95，1： | 1 |
| 13 | Differences in hyaluronic acid-mediated functions and signaling in arterial, microvessel, and vein-derived human endothelial cells 显示文摘 | Lokeshwar V B Seizer M G | 2000 | J Biol Chem2000，275，27： | 1 |
| 14 | EMMPRIN and its ligand cyclophilin A regulate MT1-MMP,MMP-9 and M-CSF during foam cell formation显示文摘 | Seizer P Schonberger T Schott M | 2010 | Atherosclerosis2010，209，1： | 1 |
| 15 | Platelet-leukocyte interactions in inflammation and atherothrombosis显示文摘 | May AE Langer H Seizer P | 2007 | Semin Thromb Hemost2007，33，2： | 1 |
| 16 | EMMPRIN and its ligand Cyclophilin A as novel diagnostic markers in inflammatory cardiomyopathy显示文摘 | SEIZER P GEISLER T BIGALKE B | 2011 | Int J Cardiol2011，6，49： | 1 |
| 17 | CXCL16 is a novel scavenger receptor on platelets and is associated with a- cute coronary syndrome显示文摘 | Seizer P Stellos K Selhorst G | 2011 | Thromb Haemost2011，105，6： | 1 |
| 18 | Platelet-leukocyte interactions in inflammation and atherothrombosis显示文摘 | May AE Langer H Seizer P | 2007 | Semin Thromb Hemost2007，33，2： | 1 |
| 19 | A new glass ionomer root canal sealer显示文摘 | Ray H Seizer L | | 0，，12： | 1 |
| 20 | Developmental regulation of sensory axon regeneration in the absence of growth cones显示文摘 | Jones SL Seizer ME Gallo G | 2006 | J Neurobialogy2006，14，： | 1 |
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