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| 1 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 2 | Serotonin Syndrome after Discontinuation of Olanzapine in a Combined Treatment with Duloxetine -Case Report显示文摘 | H. Himmighoffen E. Seifritz H. Boeker | 2011 | Pharmacopsychiatry2011，，02： | 1 |
| 3 | CO2 disposal by means o:显示文摘 | Seifritz W | 1990 | Nature1990，345，： | 1 |
| 4 | CO2 disposal by means of silicates显示文摘 | Seifritz W | 1990 | Nature1990，345，6275： | 1 |
| 5 | Study of emulsions显示文摘 | SEIFRITZ W | 1925 | The Journal of Physical Chemisty1925，29，： | 1 |
| 6 | Spatial independent component analysis of functional MRI time-series: to what extent do results depend on the algorithm used显示文摘 | Esposito F Formisano E Seifritz E | 2002 | Human Brain Mapping2002，16，3： | 1 |
| 7 | Cortical reorganization after acute unilateral hearing loss traced by fMRI显示文摘 | Bilecen D Seifritz E Radu EW | 2000 | Neurology2000，54，7： | 1 |
| 8 | Cortical reorganization after acute unilateral hearing loss traced by fMRI显示文摘 | BILECEN D SEIFRITZ E RADU E W | 2000 | Neurology2000，54，： | 1 |
| 9 | Spatial independent component analysis of functional MRI time-series:to what extent do results depend on the algorithm used显示文摘 | Esposito F Formisano E Seifritz E | 2002 | Human Brain Mapping2002，16，： | 1 |
| 10 | The polarity correlation of reactor noise in the frequency domain显示文摘 | Seifritz W | 1969 | Nuclear Application and Technology1969，7，： | 1 |
| 11 | The information in neutron fluetuations显示文摘 | Seifritz W Albrecht D | 1970 | Nuclear Science and Engineering1970，41，： | 1 |
| 12 | An on-line subcritical reactivity meter based on a novel reactor noise analysis technique in the time domain显示文摘 | Behringer K Phildius K Seifritz W | 1975 | Annals of Nuclear Energy1975，2，： | 1 |
| 13 | Non-linear burn-up waves in opaque neutron absorbers显示文摘 | SEIFRITZ W | 1995 | Kernteehnik1995，60，4： | 1 |
| 14 | CO2 disposal by means of silicates 显示文摘 | Seifritz W | 1990 | Nature1990，345，： | 1 |
| 15 | An fMRI study on mental pain and suicidal behavior显示文摘 | Reisch T Seifritz E Esposito F | 2010 | Journal of Affective Disorders2010，126，12： | 1 |
| 16 | Spatiotemporal pattern of neu ral processing in the human auditory cortex显示文摘 | Seifritz E Esposito F Hennel F | 2002 | Science2002，297，： | 1 |
| 17 | Study of emulsions 显示文摘 | Seifritz W | 1925 | J Phys Chem1925，29，： | 1 |
| 18 | CO2 disposal by means of silicates显示文摘 | Seifritz W | 1990 | Nature1990，345，： | 1 |
| 19 | CO2 disposal by means of silicates 显示文摘 | Seifritz W | 1990 | Nature1990，345，： | 1 |
| 20 | Sleep dectroencep- halographic response to muscacinic with major depression and in normal cantrois显示文摘 | Seifritz E Gillin JC Rapaport MH | 1998 | Biol Psychiatry1998，44，1： | 1 |
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