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| 1 | Portal vein thrombosis with protein C-S deficiency in a noncirrhotic patient显示文摘There are several conditions that can lead to portal vein thrombosis(PVT), including including infection, malignancies, and coagulation disorders. Anew condition of interest is protein C and S deficiencies, associated with hypercoagulation and recurrent venous thromboembolism. We report the case of a non-cirrhotic 63-year-old male diagnosed with acute superior mesenteric vein thrombosis and PVT and combined deficiencies in proteins C and S, recanalized by short-term low molecular heparin plus oral warfarin therapy. | Gustavo A Rodríguez-Leal Segundo Morán Roberto Corona-Cedillo Rocío Brom-Valladares | 2014 | World Journal of Hepatology2014，6，7： | 10 |
| 2 | Current approach to treatment of minimal hepatic encephalopathy in patients with liver cirrhosis显示文摘Minimal hepatic encephalopathy(MHE)corresponds to the earliest stage of hepatic encephalopathy(HE).MHE does not present clinically detectable neurological-psychiatric abnormalities but is characterized by imperceptible neurocognitive alterations detected during routine clinical examination via neuropsychological or psychometrical tests.MHE may affect daily activities and reduce job performance and quality of life.MHE can increase the risk of accidents and may develop into overt encephalopathy,worsening the prognosis of patients with liver cirrhosis.Despite a lack of consensus on the therapeutic indication,interest in finding novel strategies for prevention or reversion has led to numerous clinical trials;their results are the main objective of this review.Many studies address the treatment of MHE,which is mainly based on the strategies and previous management of overt HE.Current alternatives for the management of MHE include measures to maintain nutritional status while avoiding sarcopenia,and manipulation of intestinal microbiota with non-absorbable disaccharides such as lactulose,antibiotics such as rifaximin,and administration of different probiotics.This review analyzes the results of clinical studies that evaluated the effects of different treatments for MHE. | Segundo Moran Marlene López-Sánchez María del Pilar Milke-García Gustavo Rodríguez-Leal | 2021 | World Journal of Gastroenterology2021，27，22： | 5 |
| 3 | Clinical significance of donor-specific human leukocyte antigen antibodies in liver transplantation显示文摘Antibody-mediated rejection(AMR) caused by donorspecific anti-human leukocyte antigen antibodies(DSA) is widely accepted to be a risk factor for decreased graft survival after kidney transplantation. This entity also plays a pathogenic role in other solid organ transplants as it appears to be an increasingly common cause of heart graft dysfunction and an emerging issue in lung transplantation. In contrast, the liver appears relatively resistant to DSA-mediated injury. This 'immune-tolerance' liver property has been sustained by a low rate of liver graft loss in patients with preformed DSA and by the intrinsic liver characteristics that favor the absorption and elimination of DSA; however, alloantibody-mediated adverse consequences are increasingly being recognized, and several cases of acute AMR after ABO-compatible liver transplant(LT) have been reported. Furthermore, the availability of new solid-phase assays, allowing the detection of low titers of DSA and the refinement of objective diagnostic criteria for AMR in solid organ transplants and particularly in LT, have improved the recognition and management of this entity. A cost-effective strategy of DSA monitoring, avoidance of class Ⅱ human leukocyte antigen mismatching, judicious immunosuppression attached to a higher level of clinical suspicion of AMR, particularly in cases unresponsive to conventional antirejection therapy, can allow a rational approach to this threat. | Antonio Cuadrado David San Segundo Marcos López-Hoyos Javier Crespo Emilio Fábrega | 2015 | World Journal of Gastroenterology2015，21，39： | 5 |
| 4 | Endophytic nitrogen fixation in sugarcane:present knowledge and future applications显示文摘 | Robert M B Segundo U Bruno J R Veronica R | 2003 | Plant & Soil2003，252，： | 1 |
| 5 | Dynamic and static hysteresis in crayfish receptors显示文摘 | SEGUNDO J P MARTINEZ O D | 1985 | Biol Cybern1985，52，5： | 1 |
| 6 | Thyroid-infiltrating B lymphocytes in Graves' disease are related to marginal zone and memory B cell compartments显示文摘 | Segundo C Rodriguez C Garcia-Poley A | 2001 | Thyroid2001，11，6： | 1 |
| 7 | Endophytic nitrogen fixation in sugarcane:Present knowledge and future applications显示文摘 | ROBERT M B SEGUNDO URQUIAGA BRUNO J R | 2003 | Plant and Soil2003，252，： | 1 |
| 8 | Methodological aspects about in vitro evaluation of antioxidant properties显示文摘 | Luís M. Magalh?es Marcela A. Segundo Salette Reis José L.F.C. Lima | 2008 | Analytica Chimica Acta2008，，1： | 1 |
| 9 | Bovine typeⅢinterferon significantly delays and reduces the severity of foot-and-mouth disease in cattle显示文摘 | PEREZ-MARTIN E WEISS M DIAZ-SAN SEGUNDO F | 2012 | J Virol2012，86，8： | 1 |
| 10 | Ceropin A-derived petides are potent inhibitors of fungal plant pathogens显示文摘 | Cavallarin L Andreu D San Segundo B | 1998 | Mol Plant Microbe Interact1998，11，3： | 1 |
| 11 | Peripheral blood sampling for the detection of allograft rejection:biomarker identification and validation显示文摘 | Heidt S San Segundo D Shankar S | 2011 | Transplan-tation2011，92，1： | 1 |
| 12 | Harmonic analysis in frequency and time domain 显示文摘 | Medina A Segundo - Ramirez J Ribeiro P | 2013 | IEEE Transactions on Power Delivery2013，28，3： | 1 |
| 13 | 应将引进猪群的隔离和驯化放在猪场管理的首位显示文摘虽然养护良好的车轮药浴池有助于保持猪场的生物安全,但猪场的卫生管理人员应该认识到大多数新的感染都是由新引进的猪带来的。在多点养猪生产中,通过检疫和驯化来提高猪场生物安全的做法可称为场点的首要任务,但许多商业猪场的检疫和驯化设施都需要加以改进。 | 舒畅 Ricardo Segundo | 2005 | 国外畜牧学(猪与禽)2005，，4： | 1 |
| 14 | Changes in the serum levels of interleukin-17/interleukin-23 during acute rejection in liver transplantation显示文摘 | Fabrega E Lopez-Hoyos M San Segundo D | 2009 | Liver transpl2009，15，6： | 1 |
| 15 | Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4^+CD25^+ FOXP3^+ regulatory T cells in renal transplant recipients显示文摘 | Segundo DS Ruiz JC Izquierdo M | 2006 | Transplantation2006，82，4： | 1 |
| 16 | Automatic Face Segmenta- tion and Facial Landmark Detection in Range Images 显示文摘 | Segundo M P Silva L Bellon O R P | 2010 | IEEE Trans- actions on Systems Man and Cybernetics Part B : Cybernetics2010，40，： | 1 |
| 17 | Dynamics of BNF-induced in vivo ethoxyresorufin-O-deethylase (EROD) activity during embryonic development of medaka (Oryzias latipes) 显示文摘 | Miguel Gonz lez-Doncel Laura San Segundo Salvador Sastre | 2011 | Aquatic Toxicology2011，105，： | 1 |
| 18 | Bovine Type I]I Interferon Significantly Delays and Reduces the Severity of Foot-an&Mouth Disease in Cattle 显示文摘 | Perez M E Weiss M Segundo F | 2012 | Journal of Virology2012，86，8： | 1 |
| 19 | Reg-ulatory T cells in renal transplantation and modulation by immunosup-pression显示文摘 | Lopez-Hoyos M Segundo D S Femandez-Fresnedo G | 2009 | Transplantation2009，88，3： | 1 |
| 20 | Selective lymphocyte depletion during the early stage of the immune response to foot-and-mouth disease virus infection in swine 显示文摘 | Diaz-San Segundo F Salguero FJ de Marco MM | 2006 | J Virol2006，80，5： | 1 |
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