|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Proteinase activated-receptors-associated signaling in the control of gastric cancer显示文摘Gastric cancer(GC)is the fourth most common cancer in the world and the second cause of cancer-related death.Gastric carcinogenesis is a multifactorial process,in which environmental and genetic factors interact to activate multiple intracellular signals thus leading to uncontrolled growth and survival of GC cells.One such a pathway is regulated by proteinase activated-receptors(PARs),seven transmembrane-spanning domain G protein-coupled receptors,which comprise four receptors(i.e.,PAR-1,PAR-2,PAR-3,and PAR-4)activated by various proteases.Both PAR-1 and PAR-2 are over-expressed on GC cells and their activation triggers and/or amplifies intracellular pathways,which sustain gastric carcinogenesis.There is also evidence that expression of either PAR-1 or PAR-2 correlates with depth of wall invasion and metastatic dissemination and inversely with the overall survival of patients.Consistently,data emerging from experimental models of GC suggest that both these receptors can be important targets for therapeutic interventions in GC patients.In contrast,PAR-4levels are down-regulated in GC and correlate inversely with the aggressiveness of GC,thus suggesting a negative role of this receptor in the control of GC.In this article we review the available data on the expression and role of PARs in GC and discuss whether manipulation of PAR-driven signals may be useful for interfering with GC cell behavior. | Silvia Sedda Irene Marafini Roberta Caruso Francesco Pallone Giovanni Monteleone | 2014 | World Journal of Gastroenterology2014，20，34： | 3 |
| 2 | Risk assessment of vector- borne diseases for public health governance 显示文摘 | Sedda L Morley DW Braks MA | 2014 | Public Health2014，128，12： | 1 |
| 3 | Rack-l,GAPDH3,and actin:proteins of Myzus persicae potentially involved in the transcytosis of Beet western yellows virus particles in the aphid显示文摘 | Seddas P Boissinot S Strub J M van Dorsselaer A van Regenmortel M H Pattus F | | 0，，： | 1 |
| 4 | Development and activity of Glomus intraradices as affected by co-existence with Glomus claroideum in one root system显示文摘 | Janouakova M Seddas P Mrnka L | 2009 | Mycorrhiza2009，19，6： | 1 |
| 5 | Effect of homocys teine lowering by 5-methyltetrahydrofolate on redox status in hyperhomoeysteinemia显示文摘 | Caruso R Campolo J Sedda V | 2006 | J Cardiovasc Pharmacol2006，47，54： | 1 |
| 6 | The influence of the wind in the Schrnal-lenberg virus outbreak in Europe 显示文摘 | Sedda L Rogers D J | 2013 | Sci Rep2013，3，： | 1 |
| 7 | Dorsal and ventral streams across sensory modalities显示文摘In this review, we describe the current models of dorsal and ventral streams in vision, audition and touch. Available theories take their first steps from the model of Milner and Goodale, which was developed to explain how human actions can be efficiently carried out using visual information. Since then, similar concepts have also been applied to other sensory modalities. We propose that advances in the knowledge of brain functioning can be achieved through models explaining action and perception patterns independently from sensory modalities. | Anna Sedda Federica Scarpina | 2012 | Neuroscience Bulletin2012，28，3： | 1 |
| 8 | New ideas and proven solutions for kiln fumiture made from cordierite and oxide ceramics显示文摘 | Haase W Sedda L | 1999 | Ceram Forum Int1999，76，7： | 1 |
| 9 | Monoclonal antibodies for detection,serological characterization and immunopurification of Grapevine fleck virus显示文摘 | SCHIEBER O SEDDAS A BELIN C | 1997 | European Journal of Plant Pathology1997，103，9： | 1 |
| 10 | Evaluation of the fracture resistance of reattached incisal fragments using different materials and techniques显示文摘 | Chazine M Sedda M Ounsi HF | 2011 | Dent Traumatol2011，27，1： | 1 |
| 11 | New ideas and proven solutions for kiln furniture made from cordierite and oxide ceramics 显示文摘 | HAASE W SEDDA L | 1999 | Ceram Forum Int1999，76，7： | 1 |
| 12 | Effect of homocystrine lowerling by 5-met hy tetrahydrofolate on redox status in hy- per-homocysteinemia显示文摘 | Caruso R Campolo J Sedda V | 2006 | J Cardiovase Phyarmaeol2006，47，： | 1 |
| 13 | Plasma total cysteineand cardiovascular risk burden: action and interaction显示文摘 | Benedetta De Chiara Valentina Sedda Marina Parolini | 2012 | Scientific WorldJournal2012，，： | 1 |
| 14 | Methodological insights for online estimation of induction motor parameters显示文摘 | LAROCHE E SEDDA E DURIEU C | 2008 | Control Systems Technology IEEE Transactions on2008，16，5： | 1 |
| 15 | Duckneglect: vid- eo- games based neglect rehabilitation 显示文摘 | Mainetti R Sedda A Ronchetti M | 2013 | Technology and Health Care2013，21，2： | 1 |
| 16 | Plasma total cysteineand cardiovascular risk burden: action and interaction 显示文摘 | De Chiara B Sedda V Parolini M et ai | 2012 | Scientific World Journal2012，2012，30： | 1 |
| 17 | Bullet identification: a case of a fatal huntingaccident resolved by comparison of lead shot using instrumental neutron activation analysis 显示文摘 | Capannesi G Sedda F | 1992 | Journal of Forensic Sciences1992，37，2： | 1 |
| 18 | Methodological Insights for Online Estimation of Induction Motor Parameters显示文摘 | Laroche E Sedda E Durieu C | 2008 | IEEE Transactions on Control Systems Technology2008，16，5： | 1 |
| 19 | New ideas and proven solutions for kiln furniture made from cordierite and oxide ceramics显示文摘 | Sedda L | 1999 | Ceramic Forum International1999，76，7： | 1 |
| 20 | New ideas and proven solutions for kiln furniture wade from cordierite and oxide ceramics 显示文摘 | Haase W Sedda L | 1999 | Ceramic Forum International1999，76，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员