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| 1 | Early renal failure as a cardiovascular disease:Focus on lipoprotein(a) and prothrombotic state显示文摘Patients with renal failure are at increased risk of cardiovascular events even at the earliest stages of disease.In addition to many classic cardiovascular risk factors,many conditions that are commonly identified as emerging risk factors might contribute to occurrence of cardiovascular disease.Changes in circulating levels of many of these emerging risk factors have been demonstrated in patients with early stages of renal failure caused by different types of renal disease and have been associated with detection of cardiovascular complications.However,for most of these factors evidence of benefits of correction on cardiovascular outcome is missing.In this article,we comment on the role of lipoprotein(a) and prothrombotic factors as potential contributors to cardiovascular events in patients with early renal failure. | Cristiana Catena Gian Luca Colussi Francesca Nait Francesca Pezzutto Flavia Martinis Leonardo A Sechi | 2015 | World Journal of Nephrology2015,4,3: | 4 |
| 2 | Relationship between Crohn’s disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patients显示文摘AIM: To study the association between Crohn’s disease (CD), Mycobacterium avium subspecies paratubercu- losis (MAP), and genetic factors by examining the role of natural resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms (now SLC11A1) in Sar dinian patients with CD and controls. METHODS: Thirty-seven CD patients and 34 controls with no inflammatory bowel disease (IBD) were recruited at the University of Sassari after giving written con sent. Six SCL11A1 polymorphisms previously reported to be the most significantly associated with IBD were searched. M. paratuberculosis was identified by IS900 PCR and sequencing. Logistic regression was used to cal culate odds ratios (OR) for the associations among CD presence of MAP, and 6 loci described above. RESULTS: For the first time, a strong association was observed between polymorphisms at NRAMP1 locus 823C/T and CD. While CD was strongly associated withboth NRAMP1 and MAP, NRAMP1 polymorphisms and MAP themselves were not correlated. CONCLUSION: Combined with previous work on the NOD2/CARD15 gene, it is clear that the interplay of ge- netic, infectious, and immunologic factors in the etiology of CD is complex. | Leonardo A Sechi Maria Gazouli Lee E Sieswerda Paola Molicotti Niyaz Ahmed John Ikonomopoulos Antonio M Scanu Daniela Paccagnini Stefania Zanetti | 2006 | World Journal of Gastroenterology2006,12,44: | 3 |
| 3 | Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management显示文摘 | Sechi G Serra A | 2007 | Lancet Neurol2007,6,: | 1 |
| 4 | Wernicke's encephalopathy in a woman on slimming diet显示文摘 | Sechi GP Serra A Pirastru MI | 2002 | Neurology2002,58,11: | 1 |
| 5 | Rela- tionship of fibrinogen levels and hemostatie abnormal- ities with organ damage in hypertension显示文摘 | SECHI L A ZINGARO L CATENA C | 2000 | Hyper- tension2000,36,: | 1 |
| 6 | PER 1 type beta lac tamase production in Acinetobacter baumannii is related to cell adhesion显示文摘 | Sechi LA Karadenizli A Deriu A | 2004 | Med Sci Monit2004,10,6: | 1 |
| 7 | The multiple cellular functions of the oncoprotein Golgi phosphoprotein 3 显示文摘 | Sechi S Frappaolo A Belloni G | 2015 | Oncotar- get2015,6,6: | 1 |
| 8 | Wernicke's encephalopathy:new clinical settings and recent advances in diagnosis and management显示文摘 | Sechi G P Serra A | 2007 | The Lancet Neurology2007,6,5: | 1 |
| 9 | Estimates of cancer burden in Sar- dinia显示文摘 | Budroni M Sechi O Cossu A | 2013 | Tumori2013,99,3: | 1 |
| 10 | In vitro adherence of staphylococcus epidermidis to polymethyl methacrylate and acrysof intraocular lenses显示文摘 | Pinna A Zanetti S Sechi LA | 2000 | Ophthalmology2000,107,: | 1 |
| 11 | Scar/WAVW is localized at the tips of protruding lamellipodia in living cells显示文摘 | Hahne P Sechi A Benesch S | 2001 | FEBS Lett2001,492,: | 1 |
| 12 | Clinical foilow-up in a group of Gaucher type I patients switching enzyme replacement therapy from imiglucerase to velaglucerase 显示文摘 | BEMBI B SECHI A DARDIS A | 2013 | Mol Genet Metab2013,108,2: | 1 |
| 13 | Long-term re- hal outcomes in patients with primary aldosteronism 显示文摘 | SECHI L A NOVELLO M LAPENNA R | 2006 | JAMA2006,295,22: | 1 |
| 14 | Wernicke encephalopathy after o- besity surgery: a systematic review显示文摘 | Serra A Sechi G Singh S | 2007 | Neurology2007,69,: | 1 |
| 15 | Immunization with DNA vaccines encoding different mycobacterial anti- gens elicits a Thl type immune response in lambs and protects against Mycobacterium avium subspecies paratu- berculosis infection 显示文摘 | SECHI L A MARA L CAPPAI P | 2006 | Vaccine2006,24,3: | 1 |
| 16 | Wemicke' s encephalopathy: new clinical setting and recent advance in diagnosis and management 显示文摘 | Sechi G Serra A | 2007 | Lancet Neural2007,6,5: | 1 |
| 17 | Mycobacterium avium subspecies paratuberculosis infects and multiplies in enteric glial cells显示文摘AIM: To establish the role of enteric glial cells during infection with Mycobacterium avium subspecies paratuberculosis (MAP) in Crohn's disease. METHODS: In order to establish the role of enteric glial cells during infection with M. avium subspecies paratuberculosis (MAP) in Crohn's disease, Map adhesion experiments on enteric glial cells were performed as well as expression analysis of Map sigma factors during infection. RESULTS: In this study, for the first time, we found a high affinity of MAP to enteric glial cells and we analyzed the expression of MAP sigma factors under different conditions of growth. CONCLUSION: The fact that Map showed a high affinity to the glial cells raises concerns about the complicated etiology of the Crohn's disease. Elucidation of the mechanisms whereby inflammation alters enteric neural control of gut functions may lead to novel treatments for Crohn's disease. | Leonardo A Sechi Anne Ruehl Niyaz Ahmed Donatella Usai Daniela Paccagnini Giovanna E Felis Stefania Zanetti | 2007 | World Journal of Gastroenterology2007,13,43: | 1 |
| 18 | Simple and rapid identi- fication of different species of Myeobacteria by PCR显示文摘 | Sechi L A DupreI Sanguinetti M | 1999 | Mol Cell Probes1999,13,2: | 1 |
| 19 | Detection of virulence factors in Pseudomonas aeruginosa strains isolated from contact lens-associated corneal ulcers 显示文摘 | Pinna A Usai D Sechi LA | 2008 | Cornea2008,,3: | 1 |
| 20 | In vitro adherence of Staphylococcus epidermidis to polymethyl methacrylate and acrysof intraocular lenses显示文摘 | Pinna A Zanetti S Sechi LA | 2000 | Ophthalmology2000,107,6: | 1 |