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您的检索式：作者名="Scott CForbes"
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| 1 | Individual Responses to Creatine Supplementation on Muscular Power is Modulated by Gene Polymorphisms in Military Recruits显示文摘Purpose The aim was to explore five established SNPs(rs1815739,rs1805086,rs2700352,rs28497577,and rs28357094)that are known to modulate skeletal muscle protein kinetics in response to creatine supplementation.Methods A randomized,placebo-controlled,repeated measures design was used.Participants(n=152)were rand-omized divided into one of two groups:CREA(20 g/day creatine monohydrate)or PLAC:(dextrose)for 7 days.SNP were assessed,and participants were classified accordingly.Before and after supplementation,anthropometrics(height and body mass)and performance measures(vertical jump,countermovement vertical jump,squat jump,abdominal crunches,and maximum push-ups)were assessed.Results CREA gained more body mass than PLAC(CREA:Δ0.864±0.06 kg;PLAC:Δ0.154±0.07 kg,P<0.001).In the CREA group,the presence of an A allele for the MYLK1 polymorphism was related to changes in countermovement jump height(P=0.027;effect size[d]=0.41)and leg power(P=0.040,effect size[d]=0.18).The total number of abdominal crunches after supplementation was influenced by treatments and SPP1 gene(P=0.041).A higher number of abdominal crunches was associated with the G allele in the CREA group and the TT genotype in the PLAC group(effect size[d]=0.04).Conclusion Collectively,short-term creatine supplementation increased body mass but was unable to alter muscle perfor-mance.However,following creatine supplementation,participants expressing A alleles in the MYLK1 polymorphism had a greater increase in jump height and leg power and participants expressing G alleles in the SPP1 gene had greater improve-ments in abdominal crunch performance. | Daniele Mattos Caleb Guedes MSantos Scott CForbes Darren GCandow Douglas Rosa Roberta Giovanini Busnardo Marcos Dornelas Ribeiro Dailson Paulucio Cynthia Chester Marco Machado | 2023 | Journal of Science in Sport and Exercise2023，5，1： | 0 |
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