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| 1 | Vertically acquired hepatitis C virus infection:Correlates oftransmission and disease progression显示文摘The worldwide prevalence of hepatitis C virus(HCV)infection in children is 0.05%-0.4% in developed countries and 2%-5% in resource-limited settings, where inadequately tested blood products or un-sterile medical injections still remain important routes of infection. After the screening of blood donors, motherto-child transmission(MTCT) of HCV has become the leading cause of pediatric infection, at a rate of 5%. Maternal HIV co-infection is a significant risk factor for MTCT and anti-HIV therapy during pregnancy seemingly can reduce the transmission rate of both viruses. Conversely, a high maternal viral load is an important, but not preventable risk factor, because at present no anti-HCV treatment can be administered to pregnant women to block viral replication. Caution is needed in adopting obstetric procedures, such as amniocentesis or internal fetal monitoring, that can favor fetal exposure to HCV contaminated maternal blood, though evidence is lacking on the real risk of single obstetric practices. Mode of delivery and type of feeding do not represent significant risk factors for MTCT. Therefore, there is no reason to offer elective caesarean section or discourage breast-feeding to HCV infected parturients. Information on the natural history of vertical HCV infection is limited. The primary infection is asymptomatic in infants. At least one quarter of infected children shows a spontaneous viral clearance(SVC) that usually occurs within 6 years of life. IL-28 B polymorphims and genotype 3 infection have been associated with greater chances of SVC. In general, HCV progression is mild or moderate in children with chronic infection who grow regularly, though cases with marked liver fibrosis or hepatic failure have been described. Non-organ specific autoantibodies and cryoglobulins are frequently found in children with chronic infection, but autoimmune diseases or HCV associated extrahepatic manifestations are rare. | Pier-Angelo Tovo Carmelina Calitri Carlo Scolfaro Clara Gabiano Silvia Garazzino | 2016 | World Journal of Gastroenterology2016，22，4： | 6 |
| 2 | Hepatitis B vaccination in HIV-1 infected children:double efficacy doubling the paediatric dose显示文摘 | Balbo L | 1996 | AIDS1996，10，10： | 1 |
| 3 | Legionella pneumophila pneumonia in a newborn after water birth:a new mode of transmission显示文摘 | Franzin L Scolfaro C Cabodi D | 2001 | Clin Infect Dis2001，33，9： | 1 |
| 4 | Legionella pneumophila pneumonia in a newborn afterwater birth 显示文摘 | FRANZIN L SCOLFARO C CABODI D | 2001 | Clin Infect Dis2001，33，9： | 1 |
| 5 | The coagulopathy in sepsis: significance and implications for treatment显示文摘 | Saracco P Vitale P Scolfaro C | 2011 | Pedi- atr Rep2011，303，4： | 1 |
| 6 | Planar Force Constant Method for Lattice Dynamics of Cubic InN 显示文摘 | Leite Alves H W Alves J L A Scolfaro L M R Leite J R | 2002 | Materials Science and Engineering2002，93，： | 1 |
| 7 | Phase separation suppression in InGaN epitaxial layers due to biaxial strain 显示文摘 | TABATA A TELES L K SCOLFARO L M R | 2002 | Appl Phys Lett2002，80，5： | 1 |
| 8 | Elecavnic and Magnetic Properties of SnO2/CrO2 Thin Super]attices显示文摘 | Pablo D Borges Lulsa MR Scolfaro Horcio W Leite Alves at al | 2011 | Nanoscale Research Letters2011，6，： | 1 |
| 9 | Surveillance study of healthcare-associated infections in a pediatric neurosurgery unit in Italy显示文摘 | Raffaldi I Scolfaro C Pinon M | | 0，，4： | 1 |
| 10 | The coagulopathy in sepsis: significance and implications for treatment 显示文摘 | Saracco P Vitale P Scolfaro C | 2011 | Pediatr Rep2011，3，4： | 1 |
| 11 | The coagulopathy in sepsis: significance and implications for treatment 显示文摘 | Saracco P Vitale P Scolfaro C | 2011 | Pediatric Rep2011，3，4： | 1 |
| 12 | The coagulopathy insepsis:significance and implications for treatment显示文摘 | Saracco P Vitale P Scolfaro C | 2011 | Pedi-atr Rep2011，3，4： | 1 |
| 13 | Prolonged follow up of sev- en patients affected by hepatosplenic granulomata due to catscratch disease 显示文摘 | Scolfaro C Leunga G G Bezzio S | 2008 | Eur J Pediatr2008，167，4： | 1 |
| 14 | The coagulopathy in sepsis:significance and implications for treatment显示文摘 | Saracco P Vitale P Scolfaro C | 2011 | Pediatr Rep2011，3，4： | 1 |
| 15 | The coagulopathy in sepsis: significance and implications for treatment 显示文摘 | Saracco P Vitale P Scolfaro C | 2011 | Pedi- atr Rep2011，3，4： | 1 |
| 16 | The coagulopathy in sepsis: significance and implications for treatment 显示文摘 | Saracco P Vitale P Scolfaro C el al | 2011 | Pediatr Rep2011，3，4： | 1 |
| 17 | Moxiflo-xa- cin {or the treatment of pulmonary tuberculosis in children: a single center experience显示文摘 | Garazzino S Scolfaro C Raffaldi I | 2014 | Pediatr Pul- monol2014，49，4： | 1 |
| 18 | The coagulopathy in sep- sis: significance and implications for treatment 显示文摘 | Saracco P Vitale P Scolfaro C | 2011 | Pediatr Rep2011，3，4： | 1 |
| 19 | Nosocomial infections in pediatric cardiac surgery显示文摘 | Valea M Scolfaro C Cappello N | 2001 | Infect Control Hosp Epidemiol2001，22，12： | 1 |
| 20 | Surveillance study of healthcare-associated infections in a pediatric neurosurgery unit in Italy显示文摘 | Raffaldi I Scolfaro C Pinon M | 2011 | Pediatr Neurosurg2011，47，4： | 1 |
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