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| 1 | Tumor-stroma ratio as prognostic factor for survival in rectal adenocarcinoma: A retrospective cohort study显示文摘AIM To evaluate the prognostic value of the tumor-stroma ratio(TSR) in rectal cancer.METHODS TSR was determined on hematoxylin and eosin stained histological sections of 154 patients treated for rectal adenocarcinoma without prior neoadjuvant treatment in the period 1996-2006 by two observers to assessreproducibility. Patients were categorized into three categories: TSR-high [carcinoma percentage(CP) ≥ 70%], TSR-intermediate(CP 40%, 50% and 60%) and TSR-low(CP ≤ 30%). The relation between categorized TSR and survival was analyzed using Cox proportional hazards model.RESULTS Thirty-six(23.4%) patients were scored as TSR-low, 70(45.4%) as TSR-intermediate and 48(31.2%) as TSRhigh. TSR had a good interobserver agreement(κ = 0.724, concordance 82.5%). Overall survival(OS) and disease free survival(DFS) were significantly better for patients with a high TSR(P = 0.01 and P = 0.02, respectively). A similar association existed for disease specific survival(P = 0.06). In multivariate analysis, patients without lymph node metastasis and an intermediate TSR had a higher risk of dying from rectal cancer(HR = 5.27, 95%CI: 1.54-18.10), compared to lymph node metastasis negative patients with a high TSR. This group also had a worse DFS(HR = 6.41, 95%CI: 1.84-22.28). An identical association was seen for OS. These relations were not seen in lymph node metastasis positive patients. CONCLUSION The TSR has potential as a prognostic factor for survival in surgically treated rectal cancer patients, especially in lymph node negative cases. | René Scheer Alexi Baidoshvili Shorena Zoidze Marloes AG Elferink Annefleur EM Berkel Joost M Klaase Paul J van Diest | 2017 | World Journal of Gastrointestinal Oncology2017，9，12： | 3 |
| 2 | The effects of supplier fairness on vulnerable resellers显示文摘 | KUMAR N SCHEER L K STEENKAMP J E M | 1995 | Journal of Marketing Research1995，32，2： | 1 |
| 3 | The Debt of Gratitude: Dissociating Gratitude and Indebtedness 显示文摘 | WATKINS P C SCHEER J OVNICEK M | 2006 | Cognition and Emotion2006，20，2： | 1 |
| 4 | The effects of perceived interdependence on dealer attitudes 显示文摘 | Kumar N Scheer L K Steekamp J-B E M | 1995 | Journal of Marketing Research1995，32，3： | 1 |
| 5 | Adverse metabolic and cardiovascular consequences of circadian misalignment 显示文摘 | Scheer F A J L Hilton M F Mantzoros C S | 2009 | Proc Natl Acad Sci U S A2009，106，11： | 1 |
| 6 | The effects of perceived interdependence on dealer attitudes 显示文摘 | Kumar N Scheer L K Steenkamp Jan Benedict E M | 1995 | Journal of Marketing Research1995，32，3： | 1 |
| 7 | Impact of Podoplanin ex- pression in oral squamous cell carcinoma: clinical and histopatho- logic correlations显示文摘 | Kreppel M Scheer M Drebber U | 2010 | Virehows Arch2010，456，5： | 1 |
| 8 | Customer Loyalty to Whom? Managing the Benefits and Risks of Salesperson-owned Loyalty显示文摘 | ROBERT W PALMATIER LISA K SCHEER JAN-BENEDICT E M STEENKAMP | 2007 | Journal of Marketing Research2007，44，2： | 1 |
| 9 | Incorporating Perceived Risk into Mod- els of Consumer Deal Assessment and Purchase Intent 显示文摘 | Wood C M Scheer L K | 1996 | Ad- vances in Consumer Research1996，23，1： | 1 |
| 10 | A New Approach to Solve the Traveling Salesman Problem显示文摘 | Siqueira P H Steiner M T A Scheer S | 2007 | Neurocomputing2007，70，46： | 1 |
| 11 | The Effects of Perceived Interdepend-ence on Dealer Attitudes显示文摘 | KUMARNIRMALYA SCHEER LISA K STEENKAMP JAN-BENEDICT E M | 1995 | Journal of Marketing Research1995，，3： | 1 |
| 12 | Framework for an integrated business process management显示文摘 | SCHEER A W NUTTGENS M | 1995 | Wirtschaftsinformatik1995，37，5： | 1 |
| 13 | A 160-kD systemin receptor on the surface of Lycoper-sicon peruvianum cultured ceils 显示文摘 | SCHEER J M RYAN C A | 1999 | Plant Cell1999，11，： | 1 |
| 14 | Total dissociative electron attachment cross sections for molecular constit- uents of DNA显示文摘 | Aflatooni K Scheer A M Burrow P D | 2006 | J Chem Phys2006，125，05： | 1 |
| 15 | Phycobilin : cystein-84 biliprotein lyase, a near-universal lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins 显示文摘 | Zhao K H Su P Tu J M Wang X Liu H Ploscher M Eichacker L Yang B Zhou M Scheer H | 2007 | PNAS2007，104，14： | 1 |
| 16 | Characterization of phycoviolobilin phycoerythrocyanin-α84-cystein-lyase-( isomerizing) from Mastigocladus laminosus 显示文摘 | Zhao K H Wu D Wang L Zhou M Storf M Bubenzer C Strohmann B Scheer H | 2002 | Eur J Biochem2002，269，： | 1 |
| 17 | The systemin receptor SR160 from Lycopersicon peruvianum is a member of the LRR receptor kinase family 显示文摘 | Scheer J M Ryan C A Jr | 2002 | Proceedings of the National Academy of Sciences of the United States of America2002，99，14： | 1 |
| 18 | Critical limb ischaemia is characterised by an increased production of whole blood reactive oxygen species and expression of TREM-1 on neutrophils 显示文摘 | Dopheide JF Doppler C Scheer M | 2013 | Atheroselerosis2013，29，2： | 1 |
| 19 | Orbscan: a new device for iridocorneal angle measurement显示文摘 | Allouch C Touzeau O Borderie V Puech M Ameline B Scheer S Laroche L | 2002 | J Fr Ophtalmol (S0181-5512)2002，25，8： | 1 |
| 20 | The Effects of Trust and Interdependence on Relationship Commitment: A Trans- Atlantic Study 显示文摘 | Geyskens Inge Jan - Bendlct E M Steenkamp Lisa K Scheer Nirmalya Kumar | 1996 | International Journal of Research in Marketing1996，，13： | 1 |
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