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| 1 | Investigation of fundo-antral reflex in human beings显示文摘AIM: To examine the sensory and motor response(s)of the stomach following fundic distention and to assess whether cholinergic mechanisms influence these responses.METHODS: Fundic tone, gastric sensory responses and antral motility were evaluated in eight healthy volunteers after a probe with two sensors was placed in the antrum and a highly compliant balloon in the fundus. Isobaric balloon distentions were performed with a barostat.Study was repeated in six volunteers after intravenous atropine was given.RESULTS: Fundic distention induced large amplitude antral contractions in all subjects. The area under the curve was higher (P<0.05) during fundic distention.First sensation was reported at 12±4 mmHg,moderate sensation at 18±4 mmHg and discomfort at 21±4 mmHg. Discomfort was associated with a decrease in antral motility. After atropine was given, the area under the curve of pressure waves and fundic tone decreased (P<0.05). Sensory thresholds were not affected.CONCLUSIONS: Fundic balloon distention induces an antral motor response, the fundo-antral reflex, which in part may be mediated by cholinergic mechanisms. | Satish SC Rao Anjana Kumar Brent Harris Bruce Brown Konrad S Schulze | 2005 | World Journal of Gastroenterology2005，11，42： | 1 |
| 2 | Rao, MD, PhD, FACG, AGAF, FRCP (Lon), What is necessary to diagnose constipation 显示文摘 | Satish SC | 2011 | Best Practice : Research Clinical Gastroenterolo- gy2011，25，2： | 1 |
| 3 | Manometric tests of anorectal function on healthy adults显示文摘 | Satish SC Rao MD Sheila RN | 1999 | Am J Gastroenterol1999，94，3： | 1 |
| 4 | Clinical Utility of Diagnostic Tests for Constipation in Adults: A Systematic Review显示文摘 | Rao Satish SC | 2005 | American Journal of Gastroenterology2005，100，： | 1 |
| 5 | What is necessary to diagnose constipation?显示文摘 | Satish SC | 2011 | Best Practice & Research Clinical Gastroenterology2011，25，1： | 1 |
| 6 | Treatment of Esophageal (Non-cardiac) Chest Pain: Review 显示文摘 | ENRIQUE COSS-ADAME ASK1N ERDOGAN SATISH SC RAO | 2014 | Clin Gastroenterol Hepatol2014，12，8： | 1 |
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