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		题名	作者	年代	出处	被引量
	1	Inner-View of Nanomaterial Incited Protein Conformational Changes: Insights into Desig显示文摘Nanoparticle bioreactivity critically depends upon interaction between proteins and nanomaterials(NM).Te formation of the“protein corona”(PC)is the efect of such nanoprotein interactions.PC has a wide usage in pharmaceuticals,drug delivery,medicine,and industrial biotechnology.Terefore,a detailed in-vitro,in-vivo,and in-silico understanding of nanoprotein interaction is fundamental and has a genuine contemporary appeal.NM surfaces can modify the protein conformation during interaction,or NMs themselves can lead to self-aggregations.Both phenomena can change the whole downstream bioreactivity of the concerned nanosystem.Te main aim of this review is to understand the mechanistic view of NM-protein interaction and recapitulate the underlying physical chemistry behind the formation of such complicated macromolecular assemblies,to provide a critical overview of the diferent models describing NM induced structural and functional modifcation of proteins.Te review also attempts to point out the current limitation in understanding the feld and highlights the future scopes,involving a plausible proposition of how artifcial intelligence could be aided to explore such systems for the prediction and directed design of the desired NM-protein interactions.	Arka Mukhopadhyay Sankar Basu Santiswarup Singha Hirak K.Patra	2018	Research2018，，1：	2

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