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| 1 | Opti- mized Parameters for Sealing Correlation Energy显示文摘 | FAST P L CORCHADO J SANCHES M L | 1999 | Jour- nal of Physical Chemistry A1999，103，17： | 1 |
| 2 | Study of the diffusion coefficients of diphenylbutadiene and triclosan into and within meat显示文摘 | Sanches Silva A Freire J M C Losada P P | 2010 | European Food Research and Technology2010，230，6： | 1 |
| 3 | Retrostemal goiters:safety of surgical treatment显示文摘 | PAR RA-MEMB R IVE S P SANCHE Z-BLANC 0 J M GOME Z-RUBlO D et a1 | 2003 | Int Surg2003，88，20： | 1 |
| 4 | Deep venous thrombosis in patients with acute pulmonary embolism:prevalence,risk factors,and clinical significance显示文摘 | Girard P Sanche Z leroyer C | 2005 | Chest2005，128，： | 1 |
| 5 | Method of Determination of Nitrosamines in Sausages by CO2 Supercritical Fluid Extraction (SFE) and Micellar Electrokinetic Chromatography (MEKC) 显示文摘 | SANCHES FILHO P J RIOS A VALCARCEL M | 2007 | Journal of Agricultural and Food Chemistry2007，55，3： | 1 |
| 6 | Ultrafiltration of bentonite suspensions with hollow fibers membranes显示文摘 | Gourgues C Aimar P Sanche Z V | 2001 | Membr Sei2001，74，： | 1 |
| 7 | Exon duplication and divergence in the human preproglucagon gene 显示文摘 | BELL G I SANCHES P R LAYBOUM P J | 1983 | Nature1983，304，： | 1 |
| 8 | Preparation of lithium-boron alloys: electrochemical studies as anodes in molten salt media and comparison with pure lithium-involving systems 显示文摘 | Sanches P Belin C Crepy G | 1992 | Journal of Materials Science1992，27，： | 1 |
| 9 | Thoracoscopic management of primary spontaneous pneumothorax 显示文摘 | Santillan - Doherty P Argote - Greene L M Guzman - Sanche M | 2006 | Am Surg2006，72，2： | 1 |
| 10 | Validation of a Brazilian quantitative sensory testing (QST) device for the diagnosis of small fiber neuropathies 显示文摘 | Schestatsky P Stefani LC Sanches PR | 2011 | Arg Neuropsiquiatr2011，69，6： | 1 |
| 11 | Production and Structure Characterization of Recombinant Chromogranin A N-terminal Fragments (Vasostatins) Evidence of Dime-monomer Equilibria显示文摘 | CORTI A SANCHES L P GASPARRI A | 1997 | European Journal Biochemistry1997，248，： | 1 |
| 12 | Estimation of environmental risks in construetion projects in Puebla (Mexico): a neural network approach 显示文摘 | MARIA - SANCHE Z P | 2004 | Management Information Systems2004，，9： | 1 |
| 13 | Deep venous thrombosis in patients with acute pulmonary embolism: Prevalence, risk factors, and clinical significance显示文摘 | Girard P Sanche Z Leroyer C | 2005 | Chest2005，128，： | 1 |
| 14 | Two field radical lymohadenectomy in the treatment of esophageal carcinoma 显示文摘 | Torres A J Sanche P A Hernado F | 1999 | Dis Esophagus1999，12，2： | 1 |
| 15 | Characterization of polyurethane resins by FTIR, TGA, and XRD显示文摘 | Trovati G Sanches E A Claro Neto S Masearenhas Y P Chierice G O | 2010 | Journal of Applied Polymer Science2010，115，1： | 1 |
| 16 | Determination of nitrosamines in preserved sausages by solid-phase extraction-micellar electrokinetic chromatography 显示文摘 | SANCHES F P J RIOS A VALCARCEL M | 2003 | Journal of Chromatography A2003，985，12： | 1 |
| 17 | Detection of Helicobacter pylori resistance to clarithromycin and fluoroquinolones in Brazil:A national survey显示文摘AIM To evaluate bacterial resistance to clarithromycin and fluoroquinolones in Brazil using molecular methods.METHODS The primary antibiotic resistance rates of Helicobacter pylori(H. pylori) were determined from November 2012 to March 2015 in the Southern,South-Eastern,Northern,North-Eastern,and Central-Western regions of Brazil. Four hundred ninety H. pylori patients [66% female,mean age 43 years(range: 18-79)] who had never been previously treated for this infection were enrolled. All patients underwent gastroscopy with antrum and corpus biopsies and molecular testing using Geno Type Helico DR(Hain Life Science,Germany). This test was performed to detect the presence of H. pylori and to identify point mutations in the genes responsible for clarithromycin and fluoroquinolone resistance. The molecular procedure was divided into three steps: DNA extraction from the biopsies,multiplex amplification,and reverse hybridization. RESULTS Clarithromycin resistance was found in 83(16.9%) patients,and fluoroquinolone resistance was found in 66(13.5%) patients. There was no statistical difference in resistance to either clarithromycin or fluoroquinolones(P = 0.55 and P = 0.06,respectively) among the different regions of Brazil. Dual resistance to clarithromycin and fluoroquinolones was found in 4.3%(21/490) of patients. The A2147 G mutation was present in 90.4%(75/83),A2146 G in 16.9%(14/83) and A2146 C in 3.6%(3/83) of clarithromycin-resistant patients. In 10.8%(9/83) of clarithromycin-resistant samples,more than 01 mutation in the 23 S r RNA gene was noticed. In fluoroquinolone-resistant samples,37.9%(25/66) showed mutations not specified by the Geno Type Helico DR test. D91 N mutation was observed in 34.8%(23/66),D91 G in 18.1%(12/66),N87 K in 16.6%(11/66) and D91 Y in 13.6%(9/66) of cases. Among fluoroquinolone-resistant samples,37.9%(25/66) showed mutations not specified by the Geno Type Helico DR test. CONCLUSION The H. pylori clarithromycin resistance rate in Brazil is at the borderline(15%-20%) for applying the standard triple therapy. The fluoroquinolone resistance rate(13.5%) is equally concerning. | Bruno Squarcio Sanches Gustavo Miranda Martins Karine Lima Bianca Cota Luciana Dias Moretzsohn Laercio Tenorio Ribeiro Helenice P Breyer Ismael Maguilnik Aline Bessa Maia Joffre Rezende-Filho Ana Carolina Meira Henrique Pinto Edson Alves Ramiro Mascarenhas Raissa Passos Julia Duarte de Souza Osmar Reni Trindade Luiz Gonzaga Coelho | 2016 | World Journal of Gastroenterology2016，22，33： | 1 |
| 18 | Exon duplication and divergence in the human preproglucagon gene显示文摘 | Bell G I Sanches P R Layboum P J | 1983 | Nature1983，304，： | 1 |
| 19 | A Randomized Comparison of Drug-Eluting Balloon Versus Everolimus-Eluting Stent in Patients With Bare-Metal Stent In-Stent Restenosis: The RIBS V Clinical Trial显示文摘 | Fernando Alfonso Maria Jose Pérez-Vizcayno Alberto Cárdenas Bruno García del Blanco Bernhard Seidelberger Andrés I?iguez Manuel Gómez-Recio Mónica Masotti M. Teresa Velázquez Juan Sanchís Arturo García-Touchard Javier Zueco Armando Bethencourt Rafael Melg | 2013 | Journal of the American College of Cardiology2013，，： | 1 |
| 20 | The synthesis,structure-activity,and structure-side effect relationships of a series of 8-alkoxy-and 5-amino-8-alkoxyquinolone antibacterial agents显示文摘 | Joseph P Sanche Z Rocco D | 1995 | J Med Chem1995，38，22： | 1 |
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